Meclorisone is a synthetic corticosteroid exerting anti-inflammatory activity.

Prednival is prednisolone derivative patented by Francesco Vismara, Societa per Azioni as anti-inflammatory and progestational agent.

Fenestrel (ORF-3858) is a nonsteroidal antizygotic compound. It antagonizes progesterone. Fenestrel is a post-coital contraceptive.

Topterone is an anti-androgen agent. Topterone inhibited stimulation of flank organ development of castrated immature male hamsters by both testosterone and dihydrotestosterone. Topical application of topterone on the flank organs of the male hamster did not cause any significant effect on testosterone metabolism of this tissue. In addition, there was no decrease in the lipogenic capacity of the flank organ. Topterone exerts its antiandrogenic action by binding with the cytosolic androgen receptor(s) in the flank organ thus inhibiting the action of dihydrotestosterone. Systemic administration demonstrated that topterone was both antiandrogenic and progestational. Topterone produced a mean inhibition of sebum excretion of 20% when it was applied topically for four weeks to the forehead skin of patients with acne.

Ethynerone (MK 665) is an oral contraceptive steroid. In preclinical studies, it induced mammary tumors.

Procinonide is a derivative of fluocinolone acetonide that has been applied topically with fluocinonide and ciprocinonide in the management of various skin disorders.

Thyromedan is a thyroalkanoic acid derivative with hypocholesterolemic activity. In clinical trials, Thyromedan in daily doses of 8 to 32 mg caused a decrease in serum cholesterol levels. The serum total triglycerides and the α- and β-lipoprotein partition of cholesterol and triglycerides were unaffected.

Thyroxine I-131 is a radiolabeled thyroid hormone that has been studied as a diagnostic agent for thyroid cancer. In pharmacokinetic studies, Thyroxine I-131 shows broad tissue distribution and 99% of the ingested radiolabeled Thyroxine may be found in the skin, intestines, muscles, blood, bones, liver, and thyroid glands of rats.

Fluocinolone participated in clinical trials for the treatment of Oral Lichen Planus and Candida Infection.

Clomegestone (clomagestone) is an investigational steroidal progestogen. Clomegestone exhibits anti-estrogenic activity in estrone stimulated immature mice when administered orally at 100 ug.