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Details

Stereochemistry ABSOLUTE
Molecular Formula C15H11I4NO4
Molecular Weight 792.8766
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of THYROXINE I-131

SMILES

N[C@@H](CC1=CC([131I])=C(OC2=CC([131I])=C(O)C([131I])=C2)C([131I])=C1)C(O)=O

InChI

InChIKey=XUIIKFGFIJCVMT-LRAKGTFSSA-N
InChI=1S/C15H11I4NO4/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23/h1-2,4-5,12,21H,3,20H2,(H,22,23)/t12-/m0/s1/i16+4,17+4,18+4,19+4

HIDE SMILES / InChI
Thyroxine I-131 is a radiolabeled thyroid hormone that has been studied as a diagnostic agent for thyroid cancer. In pharmacokinetic studies, Thyroxine I-131 shows broad tissue distribution and 99% of the ingested radiolabeled Thyroxine may be found in the skin, intestines, muscles, blood, bones, liver, and thyroid glands of rats.

Originator

Sources: Farmaco, Edizione Scientifica (1956), 11, 484-5.

Approval Year

PubMed

PubMed

TitleDatePubMed
Preparation of I-131-tyrosines and I-131-thyroxine.
1966 Feb
Patents

Patents

Sample Use Guides

Wistar Albino Rats: 50— 100mkCi
Route of Administration: Oral
Name Type Language
THYROXINE I-131
Common Name English
THYROXINE I 131 [USAN]
Common Name English
THYROXINE I 131
USAN  
USAN  
Official Name English
L-TYROSINE, O-(4-HYDROXY-3,5-DIIODOPHENYL)-3,5-DIIODO-, LABELED WITH IODINE-131
Systematic Name English
THYROXINE (131I)
Common Name English
THYROXINE, I-131
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C1553
Created by admin on Fri Dec 15 15:18:45 GMT 2023 , Edited by admin on Fri Dec 15 15:18:45 GMT 2023
Code System Code Type Description
FDA UNII
66847MKV84
Created by admin on Fri Dec 15 15:18:45 GMT 2023 , Edited by admin on Fri Dec 15 15:18:45 GMT 2023
PRIMARY
CAS
7525-17-9
Created by admin on Fri Dec 15 15:18:45 GMT 2023 , Edited by admin on Fri Dec 15 15:18:45 GMT 2023
ALTERNATIVE
NCI_THESAURUS
C152596
Created by admin on Fri Dec 15 15:18:45 GMT 2023 , Edited by admin on Fri Dec 15 15:18:45 GMT 2023
PRIMARY
EPA CompTox
DTXSID40220462
Created by admin on Fri Dec 15 15:18:45 GMT 2023 , Edited by admin on Fri Dec 15 15:18:45 GMT 2023
PRIMARY
CAS
7019-69-4
Created by admin on Fri Dec 15 15:18:45 GMT 2023 , Edited by admin on Fri Dec 15 15:18:45 GMT 2023
PRIMARY
ChEMBL
CHEMBL42115
Created by admin on Fri Dec 15 15:18:45 GMT 2023 , Edited by admin on Fri Dec 15 15:18:45 GMT 2023
PRIMARY
PUBCHEM
3032526
Created by admin on Fri Dec 15 15:18:45 GMT 2023 , Edited by admin on Fri Dec 15 15:18:45 GMT 2023
PRIMARY