ETHYNERONE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C20H23ClO2
Molecular Weight	330.848
Optical Activity	UNSPECIFIED
Defined Stereocenters	4 / 4
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of ETHYNERONE

Structure Search

SMILES

[H][C@@]12CC[C@@](O)(C#CCl)[C@@]1(C)CCC3=C4CCC(=O)C=C4CC[C@@]23[H]

InChI

InChIKey=KEOBKPHJNAILCW-FUMNGEBKSA-N

InChI=1S/C20H23ClO2/c1-19-8-6-16-15-5-3-14(22)12-13(15)2-4-17(16)18(19)7-9-20(19,23)10-11-21/h12,17-18,23H,2-9H2,1H3/t17-,18+,19+,20-/m1/s1

HIDE SMILES / InChI

Molecular Formula	C20H23ClO2
Molecular Weight	330.848
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	4 / 4
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/3358452 | https://www.ncbi.nlm.nih.gov/pubmed/6930510 | https://www.ncbi.nlm.nih.gov/pubmed/411941 | https://www.ncbi.nlm.nih.gov/pubmed/650701

Ethynerone (MK 665) is an oral contraceptive steroid. In preclinical studies, it induced mammary tumors.

Approval Year

PubMed

PubMed

Title	Date	PubMed
Mammary nodules in beagle dogs administered investigational oral contraceptive steroids.	1978 Jun	650701
The morphologic effects of synthetic reproductive steroids on the mammary gland of rhesus monkeys. Mestranol, ethynerone, mestranol-ethynerone, chloroethynyl norgestrel-mestranol, and anagestone acetate-mestranol combinations.	1988 May	3358452

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:20:26 UTC 2023` Edited by `admin` on `Fri Dec 15 15:20:26 UTC 2023`
Record UNII	CKM4S0R7LX
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ETHYNERONE

Official Name

English

ethynerone [INN]

Common Name

English

19-NORPREGNA-4,9-DIEN-20-YN-3-ONE, 21-CHLORO-17-HYDROXY-, (17.ALPHA.)-

Common Name

English

ETHYNERONE [USAN]

Common Name

English

21-Chloro-17-hydroxy-19-nor-17α-pregna-4,9-dien-20-yn-3-one

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C776

Created by admin on Fri Dec 15 15:20:26 UTC 2023 , Edited by admin on Fri Dec 15 15:20:26 UTC 2023

Code System Code Type Description

CAS

3124-93-4

Created by admin on Fri Dec 15 15:20:26 UTC 2023 , Edited by admin on Fri Dec 15 15:20:26 UTC 2023

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INN

2038

Created by admin on Fri Dec 15 15:20:26 UTC 2023 , Edited by admin on Fri Dec 15 15:20:26 UTC 2023

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ChEMBL

CHEMBL2104303

Created by admin on Fri Dec 15 15:20:26 UTC 2023 , Edited by admin on Fri Dec 15 15:20:26 UTC 2023

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PUBCHEM

10336790

Created by admin on Fri Dec 15 15:20:26 UTC 2023 , Edited by admin on Fri Dec 15 15:20:26 UTC 2023

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NCI_THESAURUS

C74366

Created by admin on Fri Dec 15 15:20:26 UTC 2023 , Edited by admin on Fri Dec 15 15:20:26 UTC 2023

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EVMPD

SUB07293MIG

Created by admin on Fri Dec 15 15:20:26 UTC 2023 , Edited by admin on Fri Dec 15 15:20:26 UTC 2023

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MESH

C016442

Created by admin on Fri Dec 15 15:20:26 UTC 2023 , Edited by admin on Fri Dec 15 15:20:26 UTC 2023

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EPA CompTox

DTXSID10185170

Created by admin on Fri Dec 15 15:20:26 UTC 2023 , Edited by admin on Fri Dec 15 15:20:26 UTC 2023

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SMS_ID

100000082070

Created by admin on Fri Dec 15 15:20:26 UTC 2023 , Edited by admin on Fri Dec 15 15:20:26 UTC 2023

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WIKIPEDIA

Ethynerone

Created by admin on Fri Dec 15 15:20:26 UTC 2023 , Edited by admin on Fri Dec 15 15:20:26 UTC 2023

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FDA UNII

CKM4S0R7LX

Created by admin on Fri Dec 15 15:20:26 UTC 2023 , Edited by admin on Fri Dec 15 15:20:26 UTC 2023

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Related Record Type Details


					CKM4S0R7LX

ACTIVE MOIETY