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Details

Stereochemistry ABSOLUTE
Molecular Formula C26H38O2
Molecular Weight 382.5787
Optical Activity UNSPECIFIED
Defined Stereocenters 6 / 6
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of QUINGESTRONE

SMILES

[H][C@@]12CC[C@H](C(C)=O)[C@@]1(C)CC[C@@]3([H])[C@@]2([H])CC=C4C=C(CC[C@]34C)OC5CCCC5

InChI

InChIKey=XAVRSHOUEXATJE-FBQZJRKBSA-N
InChI=1S/C26H38O2/c1-17(27)22-10-11-23-21-9-8-18-16-20(28-19-6-4-5-7-19)12-14-25(18,2)24(21)13-15-26(22,23)3/h8,16,19,21-24H,4-7,9-15H2,1-3H3/t21-,22+,23-,24-,25-,26+/m0/s1

HIDE SMILES / InChI

Molecular Formula C26H38O2
Molecular Weight 382.5787
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 6 / 6
E/Z Centers 0
Optical Activity UNSPECIFIED

Description

Quingestrone is a progestin, or a synthetic progestogen, patented by Laboratoires francais de chimiotherapie as an anti-inflammatory agent. Quingestrone acts as an agonist of the progesterone receptor weak glucocorticoid activity. Quingestrone was formerly used in combination with ethinylestradiol or mestranol in combined birth control pills in Italy. The medication was studied in the clinical prevention of miscarriage during pregnancy, but insufficient efficacy was observed at the dosage assessed

Originator

Approval Year

PubMed

Patents

Sample Use Guides

In Vivo Use Guide
100 mg/day
Route of Administration: Oral
Substance Class Chemical
Record UNII
0612VZ9I5Z
Record Status Validated (UNII)
Record Version