Approval Year
| Substance Class |
Protein
Created
by
admin
on
Edited
Sat Dec 16 13:06:12 GMT 2023
by
admin
on
Sat Dec 16 13:06:12 GMT 2023
|
| Protein Type | RECEPTOR |
| Protein Sub Type | |
| Sequence Origin | HUMAN |
| Sequence Type | COMPLETE |
| Record UNII |
TB2Q79LBS0
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
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Common Name | English | ||
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Code | English | ||
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Common Name | English | ||
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Code | English | ||
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Common Name | English | ||
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Common Name | English | ||
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Common Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
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2628
Created by
admin on Sat Dec 16 13:06:13 GMT 2023 , Edited by admin on Sat Dec 16 13:06:13 GMT 2023
|
PRIMARY | |||
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P11836
Created by
admin on Sat Dec 16 13:06:13 GMT 2023 , Edited by admin on Sat Dec 16 13:06:13 GMT 2023
|
PRIMARY | |||
|
TB2Q79LBS0
Created by
admin on Sat Dec 16 13:06:13 GMT 2023 , Edited by admin on Sat Dec 16 13:06:13 GMT 2023
|
PRIMARY |
| From | To |
|---|---|
| 1_167 | 1_183 |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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LIGAND->TARGET |
BINDING
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INHIBITOR -> TARGET | |||
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RADIOLIGAND->TARGET |
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LIGAND->TARGET |
BINDING
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LIGAND->TARGET |
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INHIBITOR -> TARGET | |||
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INHIBITOR -> TARGET |
Fc-glycans are homogenously engineered onto the antibody and increase ADCC, anti-tumor activity and the half-life of the antibody.
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INHIBITOR -> TARGET | |||
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LIGAND->TARGET |
BINDING
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INHIBITOR -> TARGET | |||
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LIGAND->TARGET | |||
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LIGAND->TARGET |
TRU-015 depletes B-cells from the peripheral blood in vitro, and can mediate complement-and antibody-dependent cellular cytotoxicity.
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LIGAND->TARGET |
BINDING
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INHIBITOR -> TARGET | |||
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LIGAND->TARGET |
BINDING
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LIGAND->TARGET |
BINDING
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ACTIVATOR -> TARGET |
CPO107 is to bind to CD20 on the target cell surface to induce the antibody-dependent cellmediated cytotoxicity (ADCC) and complement-dependent cytotoxicity (CDC)
IN-VIVO
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LIGAND->TARGET |
BINDING
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CYTOTOXIC T-CELL->TARGET |
secrete interferon gamma in response to CD19 and CD20
expressing tumour cell lines
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RADIOLIGAND->TARGET | |||
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INHIBITOR -> TARGET | |||
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LIGAND->TARGET | |||
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LIGAND->TARGET | |||
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INHIBITOR -> TARGET |
IN-VITRO
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ANTIGEN->TARGET | |||
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INHIBITOR -> TARGET | |||
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LIGAND->TARGET |
BINDING
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LIGAND->TARGET | |||
|
INHIBITOR -> TARGET |
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LIGAND->TARGET | |||
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LIGAND->TARGET |
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LIGAND->TARGET | |||
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LIGAND->TARGET |
| Name | Property Type | Amount | Referenced Substance | Defining | Parameters | References |
|---|---|---|---|---|---|---|
| MOL_WEIGHT | CHEMICAL |
|