U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 14:32:08 GMT 2023
Edited
by admin
on Sat Dec 16 14:32:08 GMT 2023
Protein Type BISPECIFIC ANTIBODY
Protein Sub Type IGG1
Sequence Origin HUMANIZED MOUSE
Sequence Type COMPLETE
Record UNII
06P3KLK2J8
Record Status Validated (UNII)
Record Version
  • Download
Related Record Type
Name Type Language
GLOFITAMAB
INN   USAN  
Official Name English
IMMUNOGLOBULIN G1 (149-GLUTAMIC ACID,215-GLUTAMIC ACID,461-ALANINE,462-ALANINE,556-GLYCINE,581-CYSTEINE,593-TRYPTOPHAN), ANTI-(HUMAN CD20 ANTIGEN) (HUMAN-MUS MUSCULUS MONOCLONAL RG6026 VH-CH1 FRAGMENT) FUSION PROTEIN WITH PEPTIDE (SYNTHETIC 10-AMINO ACID
Common Name English
glofitamab [INN]
Common Name English
RG-6026
Code English
GLOFITAMAB [USAN]
Common Name English
ANTI-CD20/CD3 BISPECIFIC MONOCLONAL ANTIBODY RO7082859
Common Name English
RO7082859
Code English
RO-7082859
Code English
IMMUNOGLOBULIN G1-LAMBDA/KAPPA WITH DOMAIN CROSS-OVER, ANTI-(HOMO SAPIENS MS4A1 (MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MEMBER 1, CD20)) AND ANTI-(HOMO SAPIENS CD3E (CD3 EPSILON, LEU-4)) MONOCLONAL ANTIBODY, BISPECIFIC, TRIVALENTGAMMA-LAMBDA HEAVY CHAIN
Common Name English
Glofitamab [WHO-DD]
Common Name English
Classification Tree Code System Code
FDA ORPHAN DRUG 864121
Created by admin on Sat Dec 16 14:32:08 GMT 2023 , Edited by admin on Sat Dec 16 14:32:08 GMT 2023
Code System Code Type Description
USAN
HI-119
Created by admin on Sat Dec 16 14:32:08 GMT 2023 , Edited by admin on Sat Dec 16 14:32:08 GMT 2023
PRIMARY
INN
11145
Created by admin on Sat Dec 16 14:32:08 GMT 2023 , Edited by admin on Sat Dec 16 14:32:08 GMT 2023
PRIMARY
CAS
2229047-91-8
Created by admin on Sat Dec 16 14:32:08 GMT 2023 , Edited by admin on Sat Dec 16 14:32:08 GMT 2023
PRIMARY
FDA UNII
06P3KLK2J8
Created by admin on Sat Dec 16 14:32:08 GMT 2023 , Edited by admin on Sat Dec 16 14:32:08 GMT 2023
PRIMARY
NCI_THESAURUS
C148486
Created by admin on Sat Dec 16 14:32:08 GMT 2023 , Edited by admin on Sat Dec 16 14:32:08 GMT 2023
PRIMARY
From To
1_22 1_96
1_146 1_202
1_255 1_323
1_371 1_427
1_447 5_232
1_453 2_228
1_456 2_231
1_488 1_548
1_222 3_219
1_594 1_652
2_22 2_96
2_146 2_202
2_222 4_219
2_263 2_323
2_369 2_427
1_581 2_351
3_23 3_93
3_139 3_199
4_23 4_93
4_139 4_199
5_22 5_98
5_152 5_212
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_524
N 2_299
Related Record Type Details
TARGET->LIGAND
TARGET -> ACTIVATOR
SUB_CONCEPT->SUBSTANCE
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL