U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Jun 26 18:53:20 UTC 2021
Edited
by admin
on Sat Jun 26 18:53:20 UTC 2021
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG1
Sequence Origin RAT CHIMERIC
Sequence Type COMPLETE
Record UNII
P1DFX74SQ8
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ZUBERITAMAB
INN  
Official Name English
IMMUNOGLOBULIN G1, ANTI-(HUMAN CD20 ANTIGEN) (HUMAN-MUS MUSCULUS MONOCLONAL HS006 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL HS006 .KAPPA.-CHAIN, DIMER
Common Name English
HS-006
Code English
GAMMA1 HEAVY CHAIN CHIMERIC (1-452) (VH (MUS MUSCULUS IGHV1-12*01(96.9%)-(IGHD)-IGHJ1*03 (100%)/HOMO SAPIENS IGHV1-46*01 (70.4%)-(IGHD)-IGHJ1*03 (85.7%)) (8.8.15) (1-122)-HOMO SAPIENSIGHG1*01 (100%) G1M17,1 (CH1 K120 (219) (123-220), HINGE 1-15 (221-235)
Common Name English
RHCACD20MA
Code English
ZUBERITAMAB [INN]
Common Name English
HS006
Code English
Code System Code Type Description
NCI_THESAURUS
C174825
Created by admin on Sat Jun 26 18:53:21 UTC 2021 , Edited by admin on Sat Jun 26 18:53:21 UTC 2021
PRIMARY
FDA UNII
P1DFX74SQ8
Created by admin on Sat Jun 26 18:53:21 UTC 2021 , Edited by admin on Sat Jun 26 18:53:21 UTC 2021
PRIMARY
CAS
2251143-19-6
Created by admin on Sat Jun 26 18:53:21 UTC 2021 , Edited by admin on Sat Jun 26 18:53:21 UTC 2021
PRIMARY
INN
11331
Created by admin on Sat Jun 26 18:53:21 UTC 2021 , Edited by admin on Sat Jun 26 18:53:21 UTC 2021
PRIMARY
From To
1_22 1_96
2_22 2_96
2_149 2_205
2_225 4_213
2_266 2_326
1_149 1_205
2_372 2_430
3_23 3_87
3_133 3_193
4_23 4_87
4_133 4_193
1_225 3_213
1_231 2_231
1_234 2_234
1_266 1_326
1_372 1_430
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_302
N 2_302
Related Record Type Details
TARGET -> INHIBITOR
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL