U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

2017
422
Substance Class Protein
Created
by admin
on Fri Dec 15 16:07:36 UTC 2023
Edited
by admin
on Fri Dec 15 16:07:36 UTC 2023
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG1
Sequence Origin HUMANIZED MOUSE
Sequence Type COMPLETE
Record UNII
A10SJL62JY
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
OCRELIZUMAB
INN   USAN   WHO-DD  
INN   USAN  
Official Name English
RG-1594
Code English
OCRELIZUMAB [MI]
Common Name English
OCRELIZUMAB [USAN]
Common Name English
Ocrelizumab [WHO-DD]
Common Name English
OCRELIZUMAB [PURPLE BOOK CDER]
Common Name English
IMMUNOGLOBULIN G1, ANTI-(HUMAN CD20 (ANTIGEN)) (HUMAN-MOUSE MONOCLONAL 2H7 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN-MOUSE MONOCLONAL 2H7 .KAPPA.-CHAIN, DIMER
Common Name English
OCRELIZUMAB [JAN]
Common Name English
ocrelizumab [INN]
Common Name English
PR-070769
Code English
PR070769
Code English
IMMUNOGLOBULIN G1, ANTI-(HUMAN CD20 (ANTIGEN)) (HUMAN-MOUSE MONOCLONAL 2H7 .GAMMA.1-CHAIN), DISULPHIDE WITH HUMAN-MOUSE MONOCLONAL 2H7 .KAPPA.-CHAIN, DIMER
Common Name English
OCREVUS
Brand Name English
R-1594
Code English
Classification Tree Code System Code
NCI_THESAURUS C20401
Created by admin on Fri Dec 15 16:07:36 UTC 2023 , Edited by admin on Fri Dec 15 16:07:36 UTC 2023
NDF-RT N0000175657
Created by admin on Fri Dec 15 16:07:36 UTC 2023 , Edited by admin on Fri Dec 15 16:07:36 UTC 2023
NCI_THESAURUS C574
Created by admin on Fri Dec 15 16:07:36 UTC 2023 , Edited by admin on Fri Dec 15 16:07:36 UTC 2023
WHO-ATC L04AA36
Created by admin on Fri Dec 15 16:07:36 UTC 2023 , Edited by admin on Fri Dec 15 16:07:36 UTC 2023
Code System Code Type Description
CAS
637334-45-3
Created by admin on Fri Dec 15 16:07:36 UTC 2023 , Edited by admin on Fri Dec 15 16:07:36 UTC 2023
PRIMARY
INN
8636
Created by admin on Fri Dec 15 16:07:36 UTC 2023 , Edited by admin on Fri Dec 15 16:07:36 UTC 2023
PRIMARY
LACTMED
Ocrelizumab
Created by admin on Fri Dec 15 16:07:36 UTC 2023 , Edited by admin on Fri Dec 15 16:07:36 UTC 2023
PRIMARY
ChEMBL
CHEMBL2108041
Created by admin on Fri Dec 15 16:07:36 UTC 2023 , Edited by admin on Fri Dec 15 16:07:36 UTC 2023
PRIMARY
USAN
QQ-93
Created by admin on Fri Dec 15 16:07:36 UTC 2023 , Edited by admin on Fri Dec 15 16:07:36 UTC 2023
PRIMARY
DAILYMED
A10SJL62JY
Created by admin on Fri Dec 15 16:07:36 UTC 2023 , Edited by admin on Fri Dec 15 16:07:36 UTC 2023
PRIMARY
RXCUI
1876366
Created by admin on Fri Dec 15 16:07:36 UTC 2023 , Edited by admin on Fri Dec 15 16:07:36 UTC 2023
PRIMARY
SMS_ID
100000144876
Created by admin on Fri Dec 15 16:07:36 UTC 2023 , Edited by admin on Fri Dec 15 16:07:36 UTC 2023
PRIMARY
EVMPD
SUB121707
Created by admin on Fri Dec 15 16:07:36 UTC 2023 , Edited by admin on Fri Dec 15 16:07:36 UTC 2023
PRIMARY
DRUG CENTRAL
5223
Created by admin on Fri Dec 15 16:07:36 UTC 2023 , Edited by admin on Fri Dec 15 16:07:36 UTC 2023
PRIMARY
DRUG BANK
DB11988
Created by admin on Fri Dec 15 16:07:36 UTC 2023 , Edited by admin on Fri Dec 15 16:07:36 UTC 2023
PRIMARY
WIKIPEDIA
Ocrelizumab
Created by admin on Fri Dec 15 16:07:36 UTC 2023 , Edited by admin on Fri Dec 15 16:07:36 UTC 2023
PRIMARY
NCI_THESAURUS
C66250
Created by admin on Fri Dec 15 16:07:36 UTC 2023 , Edited by admin on Fri Dec 15 16:07:36 UTC 2023
PRIMARY
MERCK INDEX
m12020
Created by admin on Fri Dec 15 16:07:36 UTC 2023 , Edited by admin on Fri Dec 15 16:07:36 UTC 2023
PRIMARY
FDA UNII
A10SJL62JY
Created by admin on Fri Dec 15 16:07:36 UTC 2023 , Edited by admin on Fri Dec 15 16:07:36 UTC 2023
PRIMARY
From To
1_22 1_96
1_149 1_205
1_225 3_213
1_231 2_231
1_234 2_234
1_266 1_326
1_372 1_430
2_22 2_96
2_149 2_205
2_225 4_213
2_266 2_326
2_372 2_430
3_23 3_87
3_133 3_193
4_23 4_87
4_133 4_193
Related Record Type Details
HIGH AFFINITY IMMUNOGLOBULIN GAMMA FC RECEPTOR I
TARGET -> SUBSTRATE
B-LYMPHOCYTE ANTIGEN CD20
TARGET->LIGAND
BINDING
B-LYMPHOCYTE ANTIGEN CD20
TARGET -> INHIBITOR
Related Record Type Details
OCRELIZUMAB
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Volume of Distribution PHARMACOKINETIC
Biological Half-life PHARMACOKINETIC
Molecular Formula CHEMICAL
MOL_WEIGHT:SEQUENCE CHEMICAL
NIH
NCATS
PRIVACY ACT
ACCESSIBILITY
DISCLAIMER
HHS VULNERABILITY DISCLOSURE
For language access assistance, contact the NCATS Public Information Officer
National Center for Advancing Translational Sciences (NCATS),
6701 Democracy Boulevard, Bethesda MD 20892-4874 • 301-594-8966