U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

2023
446
Substance Class Protein
Created
by admin
on Wed Apr 02 01:22:07 GMT 2025
Edited
by admin
on Wed Apr 02 01:22:07 GMT 2025
Protein Type BISPECIFIC ANTIBODY
Protein Sub Type IGG1
Sequence Origin HUMANIZED MOUSE
Sequence Type COMPLETE
Record UNII
D6OMY2L0WA
Record Status FAILED
Record Version
  • Download
Related Record Type
ALTERNATIVE DEFINITION for [EPCORITAMAB]
Alternative Definition
Name Type Language
EPCORITAMAB
USAN   INN  
Official Name English
Immunoglobulin G1 [234-phenylalanine, 235-glutamic acid, 265-alanine, 405-leucine], anti-(human CD3 antigen) (human-Mus musculus monoclonal IgG1-huCACAO-FEAL ?1-chain), disulfide with human-Mus musculus monoclonal IgG1-huCACAO-FEAL ?-chain, (234?231'),(2
Preferred Name English
epcoritamab [INN]
Common Name English
EPCORITAMAB [USAN]
Common Name English
Epcoritamab [WHO-DD]
Common Name English
Immunoglobulin G1-lambda/kappa, anti-[Homo sapiens CD3E (CD3 epsilon)] and anti-[Homo sapiens MS4A1 (membrane-spanning 4-domains subfamily A member 1, CD20)], monoclonal bispecific antibody; gamma1 heavy chain chimeric anti-CD3E (1-454) [VH (Mus musculus
Common Name English
GEN-3013
Code English
Classification Tree Code System Code
FDA ORPHAN DRUG 865921
Created by admin on Wed Apr 02 01:22:07 GMT 2025 , Edited by admin on Wed Apr 02 01:22:07 GMT 2025
Code System Code Type Description
DAILYMED
D6OMY2L0WA
Created by admin on Wed Apr 02 01:22:07 GMT 2025 , Edited by admin on Wed Apr 02 01:22:07 GMT 2025
PRIMARY
CAS
2134641-34-0
Created by admin on Wed Apr 02 01:22:07 GMT 2025 , Edited by admin on Wed Apr 02 01:22:07 GMT 2025
PRIMARY
SMS_ID
300000010789
Created by admin on Wed Apr 02 01:22:07 GMT 2025 , Edited by admin on Wed Apr 02 01:22:07 GMT 2025
PRIMARY
INN
11078
Created by admin on Wed Apr 02 01:22:07 GMT 2025 , Edited by admin on Wed Apr 02 01:22:07 GMT 2025
PRIMARY
USAN
KL-92
Created by admin on Wed Apr 02 01:22:07 GMT 2025 , Edited by admin on Wed Apr 02 01:22:07 GMT 2025
PRIMARY
NCI_THESAURUS
C163022
Created by admin on Wed Apr 02 01:22:07 GMT 2025 , Edited by admin on Wed Apr 02 01:22:07 GMT 2025
PRIMARY
FDA UNII
D6OMY2L0WA
Created by admin on Wed Apr 02 01:22:07 GMT 2025 , Edited by admin on Wed Apr 02 01:22:07 GMT 2025
PRIMARY
From To
1_22 1_98
1_152 1_208
1_228 3_214
1_234 2_231
1_237 2_234
1_269 1_329
1_375 1_433
2_22 2_96
2_149 2_205
2_225 4_214
2_266 2_326
2_372 2_430
3_22 3_90
3_137 3_196
4_23 4_88
4_134 4_194
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_305
N 2_302
Related Record Type Details
Epcoritamab-BYSP
SUB_CONCEPT->SUBSTANCE
B-LYMPHOCYTE ANTIGEN CD20
TARGET->LIGAND
Kd
T-CELL SURFACE GLYCOPROTEIN CD3 EPSILON CHAIN
TARGET -> ACTIVATOR
Kd
Related Record Type Details
EPCORITAMAB
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
NIH
NCATS
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