The Sponsor hypothesizes induction of cytotoxicity by GEN3013 is dependent on binding to both CD3 and CD20. By co-engaging CD3 on T cells and CD20 on B cells or tumor cells, GEN3013 induces cytotoxic synapse formation and killing of CD20-positive target cells, independent of ligation of a peptide-major histocompatibility complex (MHC) complex by the T-cell receptor (TCR).
![ALTERNATIVE DEFINITION for [EPCORITAMAB]](https://drugs.ncats.io/assets/ginas/images/protein.svg "ALTERNATIVE DEFINITION for [EPCORITAMAB]")
