U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Jun 26 20:13:24 UTC 2021
Edited
by admin
on Sat Jun 26 20:13:24 UTC 2021
Protein Type BISPECIFIC ANTIBODY
Protein Sub Type IMMUNOMODULATOR
Sequence Origin HUMANIZED MOUSE
Sequence Type COMPLETE
Record UNII
LDJ89SS0YG
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
MOSUNETUZUMAB
INN   USAN  
Official Name English
RG-7828
Code English
BTCT-4465A
Code English
MOSUNETUZUMAB [USAN]
Common Name English
IMMUNOGLOBULIN G1-KAPPA ANTI-(HOMO SAPIENS T-CELL SURFACE GLYCOPROTEIN CD3 EPSILON CHAIN (CD3E ANTIGEN)) AND IMMUNOGLOBULIN G1-KAPPA ANTI-(HOMO SAPIENS B-LYMPHOCYTE ANTIGEN CD20) HETERODIMERHUMANIZED MONOCLONAL ANTIBODY BISPECIFIC.GAMMA.1 HEAVY CHAIN ANT
Systematic Name English
RO7030816
Code English
MOSUNETUZUMAB [WHO-DD]
Common Name English
RO-7030816
Code English
IMMUNOGLOBULIN G1, HUMANIZED BISPECIFIC, ANTI-(HUMAN CD3 (ANTIGEN))(BTCT4465A .GAMMA.1-CHAIN), DISULFIDE WITH ANTI-(HUMAN CD3 (ANTIGEN)) BTCT4465A .KAPPA.4-CHAIN, ANTI-(HUMAN CD20 (ANTIGEN)) BTCT4465A .GAMMA.3-CHAIN AND ANTI-(HUMAN CD20 (ANTIGEN)) BTCT44
Systematic Name English
BTCT4465A
Code English
RG7828
Code English
MOSUNETUZUMAB [INN]
Common Name English
RG-7828 (ANTI-CD20 & CD3)
Code English
Classification Tree Code System Code
FDA ORPHAN DRUG 663418
Created by admin on Sat Jun 26 20:13:25 UTC 2021 , Edited by admin on Sat Jun 26 20:13:25 UTC 2021
Code System Code Type Description
FDA UNII
LDJ89SS0YG
Created by admin on Sat Jun 26 20:13:25 UTC 2021 , Edited by admin on Sat Jun 26 20:13:25 UTC 2021
PRIMARY
INN
10621
Created by admin on Sat Jun 26 20:13:25 UTC 2021 , Edited by admin on Sat Jun 26 20:13:25 UTC 2021
PRIMARY
CAS
1905409-39-3
Created by admin on Sat Jun 26 20:13:25 UTC 2021 , Edited by admin on Sat Jun 26 20:13:25 UTC 2021
PRIMARY
NCI_THESAURUS
C129691
Created by admin on Sat Jun 26 20:13:25 UTC 2021 , Edited by admin on Sat Jun 26 20:13:25 UTC 2021
PRIMARY
DRUG BANK
DB15434
Created by admin on Sat Jun 26 20:13:25 UTC 2021 , Edited by admin on Sat Jun 26 20:13:25 UTC 2021
PRIMARY
From To
1_22 1_96
1_149 1_205
1_266 1_326
1_372 1_430
2_22 2_96
2_146 2_202
2_263 2_323
2_369 2_427
1_225 4_213
1_231 2_228
1_234 2_231
2_222 3_219
3_23 3_94
3_139 3_199
4_23 4_87
4_133 4_193
Related Record Type Details
TARGET->LIGAND
TARGET->ANTIGEN
TARGET -> ACTIVATOR
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL