U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Jun 26 18:50:12 UTC 2021
Edited
by admin
on Sat Jun 26 18:50:12 UTC 2021
Protein Type BISPECIFIC ANTIBODY
Protein Sub Type IGG4
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
8R5CM46UIO
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ODRONEXTAMAB
INN   USAN  
Official Name English
REGN-1979
Code English
ANTI-CD20/CD3 MONOCLONAL ANTIBODY REGN1979
Common Name English
IMMUNOGLOBULIN G4-KAPPA ANTI-(HOMO SAPIENS B-LYMPHOCYTE ANTIGEN CD20), HETERO DIMER WITH IMMUNOGLOBULIN G4-KAPPA ANTI-(HOMO SAPIENS T-CELL SURFACE GLYCOPROTEIN CD3 EPSILON CHAIN) HUMAN MONOCLONAL ANTIBODY .GAMMA.4 HEAVY CHAIN (1-453) (HOMO SAPIENS VH (IG
Common Name English
ANTI-CD20 X ANTI-CD3 BISPECIFIC MONOCLONAL ANTIBODY REGN1979
Common Name English
ODRONEXTAMAB [INN]
Common Name English
IMMUNOGLOBULIN G4, ANTI-(HUMAN CD20 ANTIGEN) (HUMAN REGN1979 .GAMMA.-CHAIN), DISULFIDE WITH HUMAN REGN1979 .KAPPA.-CHAIN, DIMER WITH IMMUNOGLOBULIN G4, ANTI-(HUMAN CD3 ANTIGEN) (HUMAN REGN1979 .GAMMA.-CHAIN), DISULFIDE WITH HUMAN REGN1979 .KAPPA.-CHAIN
Common Name English
ODRONEXTAMAB [USAN]
Common Name English
MAB HUMAN (IGG4) ANTI P11836 (CD20_HUMAN) & ANTI P07766 (CD3E_HUMAN) (REGN1979)
Common Name English
REGN1979
Code English
Classification Tree Code System Code
FDA ORPHAN DRUG 623317
Created by admin on Sat Jun 26 18:50:12 UTC 2021 , Edited by admin on Sat Jun 26 18:50:12 UTC 2021
FDA ORPHAN DRUG 569816
Created by admin on Sat Jun 26 18:50:12 UTC 2021 , Edited by admin on Sat Jun 26 18:50:12 UTC 2021
Code System Code Type Description
FDA UNII
8R5CM46UIO
Created by admin on Sat Jun 26 18:50:12 UTC 2021 , Edited by admin on Sat Jun 26 18:50:12 UTC 2021
PRIMARY
NCI_THESAURUS
C119615
Created by admin on Sat Jun 26 18:50:12 UTC 2021 , Edited by admin on Sat Jun 26 18:50:12 UTC 2021
PRIMARY
INN
11035
Created by admin on Sat Jun 26 18:50:12 UTC 2021 , Edited by admin on Sat Jun 26 18:50:12 UTC 2021
PRIMARY
CAS
1801338-64-6
Created by admin on Sat Jun 26 18:50:12 UTC 2021 , Edited by admin on Sat Jun 26 18:50:12 UTC 2021
PRIMARY
From To
1_22 1_96
1_141 3_214
1_154 1_210
1_233 2_229
1_236 2_232
1_267 1_327
1_373 1_431
2_22 2_96
2_137 4_214
2_150 2_206
2_263 2_323
2_369 2_427
3_23 3_88
3_134 3_194
4_23 4_88
4_134 4_194
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_303
N 2_299
Related Record Type Details
TARGET -> ACTIVATOR
TARGET->LIGAND
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL