Approval Year
| Substance Class |
Structurally Diverse
Created
by
admin
on
Edited
Sat Dec 16 19:55:56 GMT 2023
by
admin
on
Sat Dec 16 19:55:56 GMT 2023
|
| Source Materials Class | ORGANISM |
| Source Materials Type | AUTOLOGOUS HUMAN |
| Source Materials State | LIVE GENETICALLY MODIFIED |
| Source Materials Parent | |
| Part | BLOOD |
| Fraction Name | Enriched for CD4/CD8 T Cells |
| Record UNII |
35X9XB2HBG
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
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Official Name | English | ||
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Common Name | English | ||
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Common Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
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12614
Created by
admin on Sat Dec 16 19:55:57 GMT 2023 , Edited by admin on Sat Dec 16 19:55:57 GMT 2023
|
PRIMARY | |||
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C178452
Created by
admin on Sat Dec 16 19:55:57 GMT 2023 , Edited by admin on Sat Dec 16 19:55:57 GMT 2023
|
PRIMARY | |||
|
35X9XB2HBG
Created by
admin on Sat Dec 16 19:55:57 GMT 2023 , Edited by admin on Sat Dec 16 19:55:57 GMT 2023
|
PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
TARGET->CYTOTOXIC T-CELL |
secrete interferon gamma in response to CD19 and CD20
expressing tumour cell lines
|
||
|
|
TARGET->CYTOTOXIC T-CELL |
secrete interferon gamma in response to CD19 and CD20
expressing tumour cell lines
|
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
ACTIVE MOIETY |
|
Agent Modifications
| Modification Process | Modification Role | Modification Type | Amount | Fragment Name | Fragment ID |
|---|---|---|---|---|---|
| CULTURE | EXPANSION | BIOLOGICAL | HUMAN INTERLEUKIN-2 | FNO32LO217 | |
| LENTIVIRAL TRANSFECTION | TRANSFECTION | BIOLOGICAL | Prizloncabtagene autoleucel lentiviral vector | 7U3LP6FWC7 | |
| CULTURE | ACTIVATOR | BIOLOGICAL | UNSPECIFIED SUBSTANCE | 4e4ac683 |
Structural Modifications
| Modification Type | Location Site | Location Type | Residue Modified | Extent | Fragment Name | Fragment Approval |
|---|---|---|---|---|---|---|
| INSERTED GENE EXPRESSION VECTOR | Prizloncabtagene autoleucel transgene insert | BGW3U6F3Z7 | ||||
| VECTOR EXPRESSED PROTEIN | Prizloncabtagene autoleucel expressed bispecific chimeric antigen receptor targeting CD19 and CD20 | 58B5YT3X5P |