D&C Green No. 5 is an FDA-approved, synthetic dye produced from petroleum or coal tar sources, that used in pharmaceuticals and cosmetics. D&C Green No. 5 may be safely used for coloring drugs and surgical sutures. In cosmetics, it can be used externally and in general cosmetics, including lipsticks, and cosmetics close to the eye.

D and C Red No. 28 (Red 28) FDA-approved color additive used in drugs and cosmetics, including lip and eye care products, face makeups, personal care products. It is also used in biological stains, inks, and lacquers for coating and dyeing paper. D and C Red No. 28 was also investigated for use as a fruit fly pesticide. A safe level of exposure for Red 28 is considered 1.25 mg/kg /day.

Ethyl vanillin is an important food additive and flavouring agent approved by FAO/WHO, has a vanilla odor four times that of vanillin and shows anti-mutagenic activity. It is used as flavoring agent and/or as an additive by the food, cosmetic, or pharmaceutic industries. Ethyl vanillin possesses antioxidant and anti-inflammatory properties. The antioxidant activity of ethyl vanillin was much stronger than that of vanillin in the oxidative hemolysis inhibition assay, but was the same as that of vanillin in the ORAC assay. Oral administration of ethyl vanillin to mice increased the concentration of ethyl vanillic acid, and effectively raised antioxidant activity in the plasma as compared to the effect of vanillin. The antioxidant activity of ethyl vanillin might be more beneficial than has been thought in daily health practice. The anti-angiogenic, anti-inflammatory and anti-nociceptive properties of EVA are based on its suppressive effect on the production of nitric oxide possibly via decreasing the reactive oxygen species level.

Monothioglycerol (3-Mercaptopropane-1,2-diol, thioglycerol), is a chemical compound and thiol that is used as a matrix in fast atom bombardment mass spectrometry and liquid secondary ion mass spectrometry.

D&C Red No. 27 are fluorescein-based dyes that were approved in 1982 for use in drugs and cosmetics Cosmetic retail products containing this dye is primarily lipsticks and blushers. D&C Red No. 27 physically associated with non-aqueous aluminum or zirconium minerals (lakes) and used in lipsticks, blushers, make-up preparations, hair dyes and colors, rouges and face powders. The FDA lists D&C Red No. 27 as a safe additive for drugs and cosmetics as per FDA standards.

D&C Red No. 30 is a drug and cosmetic synthetic dye. The FDA lists it as a safe additive for drugs and cosmetics as per FDA standards. In cosmetics, D&C Red No. 30 can be used externally and in general cosmetics, including lipsticks, but is not to be used in cosmetics close to the eye.

Diethylene glycol monoethyl ether (under brand name Transcutol) is used as a vehicle in the formulation or manufacturing process of pharmaceuticals, cosmetics, and food additives. Transcutol is safe for use and has low irritancy inferred by numerous toxicological studies and precedence of use in approved topical medicines.

D&C RED NO. 6 BARIUM LAKE belongs to the family of barium salt of carboxylic acid. It is used in cosmetic manufacturing practices. The combined total of D&C RED No. 6 and D&C RED No. 7 must not exceed 5mg per daily dose of a drug.

D&C Red No. 6 is an excipient (pharmacologically inactive substance). It is FDA-approved, high-purity pigment. It can be tinted with titanium dioxide to create light red/pink shades. The color additive D&C Red No. 6 is principally the disodium salt of 3-hydroxy-4-[(4-methyl-2-sulfophenyl)azo]-2-naphthalenecarboxylic acid. To manufacture the additive, 2-amino-5-methylbenzenesulfonic acid is diazotized with hydrochloric acid and sodium nitrite. The diazo compound is coupled in alkaline medium with 3-hydroxy-2-naphthalenecarboxylic acid. The resulting dye precipitates as the disodium salt. D&C Red No. 6 is used in decorative cosmetic products including lipsticks, nail lacquers & face makeup (in USA prohibited for eye makeup), personal care products, soaps.