U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 31 - 40 of 224 results

Status:
Investigational
Source:
USAN:Actinoquinol Sodium
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

Actinoquinol is sunscreen agent that absorbs Ultraviolet B light. Actinoquinol in combination with hyaluronic acid drops might be helpful for the human eye in the defense against photooxidative and other oxidative processes.
Status:
Investigational
Source:
INN:decominol [INN]
Source URL:

Class (Stereo):
CHEMICAL (RACEMIC)

Targets:

Decominol is a bactericidal compound used in the cosmetic industry and developed by the French company Laboratoires Pharmascience. Bacteriostatic activity is claimed to be particularly significant in the case of gram-negative bacteria, especially Escherichia coli and Pseudomonas aeruginosa.
Status:
Investigational
Source:
INN:nifurizone
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Nifurizone, a 5-nitrofuran derivative, is an antibacterial agent. It was used for controlling Salmonella choleraesuis in swine. The mode of action of 5-nitrofuran analogues is based on red-ox biotransformation.
Status:
Investigational
Source:
INN:nifuralide
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Nifuralide, a 5-nitrofuran derivative, is an antibacterial agent. It was used for controlling Salmonella choleraesuis in swine. The mode of action of 5-nitrofuran analogues is based on red-ox biotransformation.
Status:
Investigational
Source:
INN:dichloroxylenol [INN]
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Dichloroxylenol is a bactericide, preservative and deodorant. It is often used in the preparation of antiseptic and deodorant lotions and bath preparations. Dichloroxylenol also showed slightly greater activity against S. aureus Oxoid 701/1 Lot 610254 than against Escherichia coli and Salmonella typhi, indicating a probable role for cell wall in the susceptibility of bacteria to dichloroxylenol. The efficacy of either povidone-iodine (Betadine) or dichloroxylenol (Septocid) intrauterine infusions on the treatment of endometritis and/or cervicitis in cows was examined. The recovery and conception rates obtained after Betadine treatment were better than those obtained after Septocid. Moreover, healthy cows and those inseminated before post-partum day 180, having no more than 4-7 previous services, responded well to either Betadine or Septocid treatment.
Status:
Investigational
Source:
INN:talmetoprim [INN]
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Talmetoprim was studied as an intestinal antibacterial agent. However, information about the further development of the drug is not available.
Status:
Investigational
Source:
INN:cloponone [INN]
Source URL:

Class (Stereo):
CHEMICAL (RACEMIC)

Cloponone is chloramphenicol derivative with antibacterial activity. It was used in combination with chloramphenicol and myralact for the treatment of trichomonal vaginitis.
Status:
Investigational
Source:
INN:crotoniazide [INN]
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Conditions:

Crotoniazide is a derivative of isonicotinic hydrazide. Crotoniazide demonstrated antituberculous activity in vitro and in vivo.
Status:
Investigational
Source:
INN:lauroguadine [INN]
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

LAUROGUADINE is a bactericide, topical antiseptic.
Status:
Investigational
Source:
INN:chaulmosulfone [INN]
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Chaulmosulfone is cyclopentanetridecananilide derivative with potent antifungal activity.