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Showing 1 - 10 of 83 results

Status:
US Approved Rx (2002)
First approved in 2002

Class (Stereo):
CHEMICAL (ACHIRAL)



Tizoxanide, the primary active metabolite of the FDA approved drug nitazoxanide, an anti-infective that has been approved for the treatment of diarrhea caused by Giardia lamblia. Tizoxanide, an active metabolite of nitazoxanide in humans, is also an ...
Status:
US Approved Rx (2016)
First approved in 1971

Class (Stereo):
CHEMICAL (ABSOLUTE)



Rifampin is an antibiotic that inhibits DNA-dependent RNA polymerase activity in susceptible cells. Specifically, it interacts with bacterial RNA polymerase but does not inhibit the mammalian enzyme. It is bactericidal and has a very broad spectrum o...
Status:
US Approved Rx (1965)
First approved in 1965

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

Ethionamide is a second-line agent, structurally similar to isoniazid, used as a second-line therapy for the treatment of multidrug-resistant tuberculosis or active tuberculosis in case of patient intolerance to other drugs. Depending on its the conc...
Status:
US Approved Rx (1964)
First approved in 1956

Class (Stereo):
CHEMICAL (ABSOLUTE)


Conditions:

Cycloserine was discovered simultaneously in 1954 by Eli Lilly and Merck. The drug was approved for the treatment of active pulmonary and extrapulmonary tuberculosis and marketed under the name Seromycin (among the others). Cycloserine suppresses the...
Status:
US Approved Rx (1971)
First approved in 1955

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

Pyrazinamide is indicated for the initial treatment of active tuberculosis in adults and children when combined with other antituberculous agents. (The current recommendation of the CDC for drug-susceptible disease is to use a six-month regimen for i...
Status:
US Approved Rx (2014)
First approved in 1952

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

Isoniazid is a bactericidal agent active against organisms of the genus Mycobacterium, specifically M. tuberculosis, M. bovis and M. kansasii. Isoniazid is recommended for all forms of tuberculosis in which organisms are susceptible. Isoniazid is a p...
Status:
US Approved Rx (1994)
First approved in 1948

Class (Stereo):
CHEMICAL (ACHIRAL)



4-AMINOSALICYLIC ACID (Paser) is an anti-tuberculosis drug used to treat tuberculosis in combination with other active agents. 4-AMINOSALICYLIC ACID (Paser) is most commonly used in patients with Multi-drug Resistant TB (MDR-TB) or when isoniazid and...
Status:
US Approved Rx (1998)
First approved in 1946

Class (Stereo):
CHEMICAL (ABSOLUTE)



Streptomycin is a water-soluble aminoglycoside derived from Streptomyces griseus. Aminoglycosides work by binding to the bacterial 30S ribosomal subunit, causing misreading of t-RNA, leaving the bacterium unable to synthesize proteins vital to its gr...
Status:
US Approved OTC
First approved in 1948

Class (Stereo):
CHEMICAL (ACHIRAL)


Thonzylamine (also known as neohetramine) is an antihistamine and anticholinergic drug, which is used in combination with others compounds for the temporarily relieves symptoms due to the common cold: hay fever (allergic rhinitis) or other upper resp...
Status:
Investigational

Class (Stereo):
CHEMICAL (ABSOLUTE)


Conditions:

TBA-354, also known as SN31354, is a potent anti-tuberculosis drug candidate. TBA-354 is narrow spectrum and bactericidal in vitro against replicating and nonreplicating Mycobacterium tuberculosis, with potency similar to that of delamanid and greate...