CLOPONONE

Details

Stereochemistry	RACEMIC
Molecular Formula	C11H9Cl4NO2
Molecular Weight	329.007
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

ClCC(NC(=O)C(Cl)Cl)C(=O)C1=CC=C(Cl)C=C1

InChI

InChIKey=MLVKMSCFQIQULM-UHFFFAOYSA-N

InChI=1S/C11H9Cl4NO2/c12-5-8(16-11(18)10(14)15)9(17)6-1-3-7(13)4-2-6/h1-4,8,10H,5H2,(H,16,18)

HIDE SMILES / InChI

Molecular Formula	C11H9Cl4NO2
Molecular Weight	329.007
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/14466299 | https://www.ncbi.nlm.nih.gov/pubmed/4946150

Cloponone is chloramphenicol derivative with antibacterial activity. It was used in combination with chloramphenicol and myralact for the treatment of trichomonal vaginitis.

Approval Year

PubMed

Title	Date	PubMed
Trichomonal vaginitis treated with one dose of metronidazole.	1971-12	4946150
Influence of dichloroacetylation on the antimicrobial activity of chloramphenicol derivatives and of various amines.	1961-10	14466299

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:31:54 GMT 2025` Edited by `admin` on `Mon Mar 31 18:31:54 GMT 2025`
Record UNII	V51W472X6D
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

(±)-2,2-DICHLORO-N-(PARA-CHLORO-ALPHA-(CHLOROMETHYL)PHENACYL)ACETAMIDE

Preferred Name

English

CLOPONONE

Official Name

English

cloponone [INN]

Common Name

English

ACETAMIDE, 2,2-DICHLORO-N-(1-(CHLOROMETHYL)-2-(4-CHLOROPHENYL)-2-OXOETHYL)-

Systematic Name

English

Cloponone [WHO-DD]

Common Name

English

CLOPONONE [MART.]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C28394