CLOPONONE

Details

Stereochemistry	RACEMIC
Molecular Formula	C11H9Cl4NO2
Molecular Weight	329.007
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

ClCC(NC(=O)C(Cl)Cl)C(=O)C1=CC=C(Cl)C=C1

InChI

InChIKey=MLVKMSCFQIQULM-UHFFFAOYSA-N

InChI=1S/C11H9Cl4NO2/c12-5-8(16-11(18)10(14)15)9(17)6-1-3-7(13)4-2-6/h1-4,8,10H,5H2,(H,16,18)

HIDE SMILES / InChI

Molecular Formula	C11H9Cl4NO2
Molecular Weight	329.007
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/14466299 | https://www.ncbi.nlm.nih.gov/pubmed/4946150

Cloponone is chloramphenicol derivative with antibacterial activity. It was used in combination with chloramphenicol and myralact for the treatment of trichomonal vaginitis.

Approval Year

PubMed

Title	Date	PubMed
Influence of dichloroacetylation on the antimicrobial activity of chloramphenicol derivatives and of various amines.	1961 Oct	14466299
Trichomonal vaginitis treated with one dose of metronidazole.	1971 Dec	4946150

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:35:05 GMT 2023` Edited by `admin` on `Fri Dec 15 16:35:05 GMT 2023`
Record UNII	V51W472X6D
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

CLOPONONE

Official Name

English

cloponone [INN]

Common Name

English

ACETAMIDE, 2,2-DICHLORO-N-(1-(CHLOROMETHYL)-2-(4-CHLOROPHENYL)-2-OXOETHYL)-

Systematic Name

English

Cloponone [WHO-DD]

Common Name

English

CLOPONONE [MART.]

Common Name

English

(±)-2,2-DICHLORO-N-(PARA-CHLORO-ALPHA-(CHLOROMETHYL)PHENACYL)ACETAMIDE

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C28394