U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 51 - 60 of 224 results

Status:
Investigational
Source:
INN:nifurprazine
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

The nitrofuran derivative, nifurprazine, is a topical antibacterial agent used mainly for the treatment of animal diseases. It is a trypanocidal drug. Nifurprazine proved to be the most promising derivative since it was redox-cycled by both T. cruzi LipDH and TR and had pronounced antiparasitic effects in cultures of T. cruzi and Trypanosoma brucei.
Status:
Investigational
Source:
INN:cyclomenol [INN]
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Cyclomenol is a bactericide compound, discovered at Institute Francais Du Petrole.
Status:
Investigational
Source:
INN:fepradinol [INN]
Source URL:

Class (Stereo):
CHEMICAL (RACEMIC)


FEPRADINOL is an analgesic, antipyretic and anti-inflammatory agent. Its anti-inflammatory activity does not seem to be related to an inhibitory effect on prostaglandin biosynthesis.
Status:
Investigational
Source:
INN:toliodium chloride
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Toliodium is a surfactant used as an antibacterial and antiseptic agent. Also, it was used as an animal food additive.
Status:
Investigational
Source:
INN:cuprimyxin [INN]
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Cuprimyxin is a topical antibiotic with considerable antibacterial, anti-yeast, and antifungal activity in veterinary applications without the irritation side effects. Cuprimyxin was formulated in cream and tested in vitro against Gram-positive and Gram-negative bacterial and fungal pathogens and yeast infections, in vivo as a cream for otic and ophthalmic infections, and as a suspension with hydrocortisone acetate for the treatment of otitis. The apparent biological mechanism of action involves alteration of the invading bacterial DNA template
Status:
Investigational
Source:
INN:fludazonium chloride
Source URL:

Class (Stereo):
CHEMICAL (RACEMIC)

FLUDAZONIUM is a topical antiinfective agent.
Status:
Investigational
Source:
INN:laurcetium bromide
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
Investigational
Source:
INN:nifurethazone
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Nifurethazone, a 5-nitrofuran derivative, is an antibacterial agent. It was used for controlling Salmonella choleraesuis in swine. The mode of action of 5-nitrofuran analogues is based on red-ox biotransformation.
Status:
Investigational
Source:
INN:furmethoxadone
Source URL:

Class (Stereo):
CHEMICAL (RACEMIC)

Furmethoxadone was developed as an antibacterial agent and was studied as an anthelmintic. Information about the current use of this compound is not available.
Status:
Investigational
Source:
INN:mequidox
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Mequidox is an antibacterial agent.