FEPRADINOL

Details

Stereochemistry	RACEMIC
Molecular Formula	C12H19NO2
Molecular Weight	209.2848
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC(C)(CO)NCC(O)C1=CC=CC=C1

InChI

InChIKey=PVOOBRUZWPQOER-UHFFFAOYSA-N

InChI=1S/C12H19NO2/c1-12(2,9-14)13-8-11(15)10-6-4-3-5-7-10/h3-7,11,13-15H,8-9H2,1-2H3

HIDE SMILES / InChI

Molecular Formula	C12H19NO2
Molecular Weight	209.2848
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: https://www.drugfuture.com/chemdata/fepradinol.html | https://www.drugs.com/international/fepradinol.html | https://www.ncbi.nlm.nih.gov/pubmed/7907874

FEPRADINOL is an analgesic, antipyretic and anti-inflammatory agent. Its anti-inflammatory activity does not seem to be related to an inhibitory effect on prostaglandin biosynthesis.

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
positive regulation of vascular permeability 2 Target ID: GO:0043117 Sources: https://www.ncbi.nlm.nih.gov/pubmed/7879696	Antagonist 2778

PubMed

Title	Date	PubMed
Effect of fepradinol on rat hind paw oedema induced by several inflammatory agents.	1993 Nov	7511161
Mechanism of anti-inflammatory action of fepradinol.	1994 Jan	7907874
Sympathomimetic drug allergy: cross-reactivity study by patch test.	2004	15554736

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:09:09 UTC 2023` Edited by `admin` on `Fri Dec 15 16:09:09 UTC 2023`
Record UNII	860MHI4WBA
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

FEPRADINOL

Official Name

English

fepradinol [INN]

Common Name

English

Fepradinol [WHO-DD]

Common Name

English

(±)-.ALPHA.-(((2-HYDROXY-1,1-DIMETHYLETHYL)AMINO)METHYL)BENZYL ALCOHOL USAN SYNONYM

Common Name

English

FEPRADINOL [MI]

Common Name

English

1-PHENYL-4,4-DIMETHYL-3-AZAPENTANE-1,5-DIOL

Systematic Name

English

BENZENEMETHANOL, .ALPHA.-(((2-HYDROXY-1,1-DIMETHYLETHYL)AMINO)METHYL)-

Systematic Name

English

FEPRADINOL [MART.]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C28394