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Search results for "EU ORPHAN DRUG|Positive" in comments (approximate match)
Status:
US Approved Rx
(2016)
Source:
BLA761038
(2016)
Source URL:
First approved in 2016
Source:
BLA761038
Source URL:
Class:
PROTEIN
Status:
US Approved Rx
(2016)
First approved in 2016
Class:
PROTEIN
Status:
US Approved Rx
(2015)
Source:
BLA125511
(2015)
Source URL:
First approved in 2015
Source:
BLA125511
Source URL:
Class:
PROTEIN
Parathyroid hormone (PTH) is an 84-amino acid peptide that regulates the function of osteoblasts and osteocytes and is secreted by the parathyroid gland in response to changes in the concentration of extracellular calcium. Parathyroid hormone is approved under the brand name NATPARA as an adjunct to calcium and vitamin D to control hypocalcemia in patients with hypoparathyroidism. It is also available for treatment of postmenopausal osteoporosis in many European countries. Parathyroid hormone is an activator of parathyroid hormone 2 receptor. In addition, was shown, that downregulation of Notch in osteoblasts and osteocytes may represent a mechanism contributing to the anabolic effects of parathyroid hormone in bone.
Status:
US Approved Rx
(2015)
Source:
BLA125561
(2015)
Source URL:
First approved in 2015
Source:
BLA125561
Source URL:
Class:
PROTEIN
Status:
US Approved Rx
(2015)
Source:
BLA125526
(2015)
Source URL:
First approved in 2015
Source:
BLA125526
Source URL:
Class:
PROTEIN
Status:
US Approved Rx
(2020)
Source:
BLA761145
(2020)
Source URL:
First approved in 2015
Source:
BLA761036
Source URL:
Class:
PROTEIN
Status:
US Approved Rx
(2015)
Source:
BLA125513
(2015)
Source URL:
First approved in 2015
Source:
BLA125513
Source URL:
Class:
PROTEIN
Status:
US Approved Rx
(2014)
Source:
BLA125460
(2014)
Source URL:
First approved in 2014
Source:
BLA125460
Source URL:
Class:
PROTEIN
Status:
US Approved Rx
(2016)
First approved in 2014
Class:
PROTEIN
Status:
US Approved Rx
(2014)
Source:
BLA125557
(2014)
Source URL:
First approved in 2014
Source:
BLA125557
Source URL:
Class:
PROTEIN
