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This repository is under review for potential modification in compliance with Administration directives.

Approval Year

2015
472
Substance Class Protein
Created
by admin
on Mon Mar 31 20:55:23 GMT 2025
Edited
by admin
on Mon Mar 31 20:55:23 GMT 2025
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG1
Sequence Origin HUMANIZED MOUSE
Sequence Type COMPLETE
Record UNII
90Z2UF0E52
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
mepolizumab [INN]
Preferred Name English
MEPOLIZUMAB
DASH   INN   USAN   WHO-DD  
USAN   INN  
Official Name English
IMMUNOGLOBULIN G1 (HUMAN-MOUSE MONOCLONAL SB-240563 .GAMMA.1-CHAIN ANTI-HUMAN INTERLEUKIN 5), DISULFIDE WITH HUMAN-MOUSE MONOCLONAL SB-240563 .KAPPA.-CHAIN, DIMER
Common Name English
MEPOLIZUMAB [USAN]
Common Name English
BOSATRIA
Brand Name English
MEPOLIZUMAB [PURPLE BOOK CDER]
Common Name English
MEPOLIZUMAB [JAN]
Common Name English
MEPOLIZUMAB [MI]
Common Name English
SB-240563
Code English
Mepolizumab [WHO-DD]
Common Name English
NUCALA
Brand Name English
Classification Tree Code System Code
FDA ORPHAN DRUG 182103
Created by admin on Mon Mar 31 20:55:23 GMT 2025 , Edited by admin on Mon Mar 31 20:55:23 GMT 2025
FDA ORPHAN DRUG 345111
Created by admin on Mon Mar 31 20:55:23 GMT 2025 , Edited by admin on Mon Mar 31 20:55:23 GMT 2025
WHO-ATC R03DX09
Created by admin on Mon Mar 31 20:55:23 GMT 2025 , Edited by admin on Mon Mar 31 20:55:23 GMT 2025
WHO-ATC L04AC06
Created by admin on Mon Mar 31 20:55:23 GMT 2025 , Edited by admin on Mon Mar 31 20:55:23 GMT 2025
EMA ASSESSMENT REPORTS NUCALA (AUTHORIZED: ASTHMA)
Created by admin on Mon Mar 31 20:55:23 GMT 2025 , Edited by admin on Mon Mar 31 20:55:23 GMT 2025
FDA ORPHAN DRUG 676218
Created by admin on Mon Mar 31 20:55:23 GMT 2025 , Edited by admin on Mon Mar 31 20:55:23 GMT 2025
EU-Orphan Drug EU/3/13/1116
Created by admin on Mon Mar 31 20:55:23 GMT 2025 , Edited by admin on Mon Mar 31 20:55:23 GMT 2025
WHO-VATC QL04AC06
Created by admin on Mon Mar 31 20:55:23 GMT 2025 , Edited by admin on Mon Mar 31 20:55:23 GMT 2025
NDF-RT N0000191872
Created by admin on Mon Mar 31 20:55:23 GMT 2025 , Edited by admin on Mon Mar 31 20:55:23 GMT 2025
Code System Code Type Description
PUBCHEM
56603701
Created by admin on Mon Mar 31 20:55:23 GMT 2025 , Edited by admin on Mon Mar 31 20:55:23 GMT 2025
PRIMARY
FDA UNII
90Z2UF0E52
Created by admin on Mon Mar 31 20:55:23 GMT 2025 , Edited by admin on Mon Mar 31 20:55:23 GMT 2025
PRIMARY
MERCK INDEX
m11905
Created by admin on Mon Mar 31 20:55:23 GMT 2025 , Edited by admin on Mon Mar 31 20:55:23 GMT 2025
PRIMARY
MESH
C434107
Created by admin on Mon Mar 31 20:55:23 GMT 2025 , Edited by admin on Mon Mar 31 20:55:23 GMT 2025
PRIMARY
RXCUI
1720597
Created by admin on Mon Mar 31 20:55:23 GMT 2025 , Edited by admin on Mon Mar 31 20:55:23 GMT 2025
PRIMARY RxNorm
DAILYMED
90Z2UF0E52
Created by admin on Mon Mar 31 20:55:23 GMT 2025 , Edited by admin on Mon Mar 31 20:55:23 GMT 2025
PRIMARY
ChEMBL
CHEMBL2108429
Created by admin on Mon Mar 31 20:55:23 GMT 2025 , Edited by admin on Mon Mar 31 20:55:23 GMT 2025
PRIMARY
DRUG CENTRAL
5061
Created by admin on Mon Mar 31 20:55:23 GMT 2025 , Edited by admin on Mon Mar 31 20:55:23 GMT 2025
PRIMARY
SMS_ID
100000090763
Created by admin on Mon Mar 31 20:55:23 GMT 2025 , Edited by admin on Mon Mar 31 20:55:23 GMT 2025
PRIMARY
INN
7876
Created by admin on Mon Mar 31 20:55:23 GMT 2025 , Edited by admin on Mon Mar 31 20:55:23 GMT 2025
PRIMARY
DRUG BANK
DB06612
Created by admin on Mon Mar 31 20:55:23 GMT 2025 , Edited by admin on Mon Mar 31 20:55:23 GMT 2025
PRIMARY
NCI_THESAURUS
C157376
Created by admin on Mon Mar 31 20:55:23 GMT 2025 , Edited by admin on Mon Mar 31 20:55:23 GMT 2025
PRIMARY
CAS
196078-29-2
Created by admin on Mon Mar 31 20:55:23 GMT 2025 , Edited by admin on Mon Mar 31 20:55:23 GMT 2025
PRIMARY
LACTMED
Mepolizumab
Created by admin on Mon Mar 31 20:55:23 GMT 2025 , Edited by admin on Mon Mar 31 20:55:23 GMT 2025
PRIMARY
EVMPD
SUB21650
Created by admin on Mon Mar 31 20:55:23 GMT 2025 , Edited by admin on Mon Mar 31 20:55:23 GMT 2025
PRIMARY
WIKIPEDIA
MEPOLIZUMAB
Created by admin on Mon Mar 31 20:55:23 GMT 2025 , Edited by admin on Mon Mar 31 20:55:23 GMT 2025
PRIMARY
USAN
KK-20
Created by admin on Mon Mar 31 20:55:23 GMT 2025 , Edited by admin on Mon Mar 31 20:55:23 GMT 2025
PRIMARY
NDF-RT
N0000191871
Created by admin on Mon Mar 31 20:55:23 GMT 2025 , Edited by admin on Mon Mar 31 20:55:23 GMT 2025
PRIMARY Interleukin-5 Antagonists [MoA]
From To
1_22 1_95
1_146 1_202
1_222 3_220
1_228 2_228
1_231 2_231
1_263 1_323
1_369 1_427
2_22 2_95
2_146 2_202
2_222 4_220
2_263 2_323
2_369 2_427
3_23 3_94
3_140 3_200
4_23 4_94
4_140 4_200
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_299
N 2_299
Related Record Type Details
INTERLEUKIN-5
TARGET -> INHIBITOR
Related Record Type Details
MEPOLIZUMAB
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:ESTIMATE CHEMICAL
Molecular Formula CHEMICAL
NIH
NCATS
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