U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

2015
472
Substance Class Protein
Created
by admin
on Mon Mar 31 21:14:10 GMT 2025
Edited
by admin
on Mon Mar 31 21:14:10 GMT 2025
Protein Sub Type
Sequence Type COMPLETE
Record UNII
K4YTU42T8G
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
SEBELIPASE ALFA
DASH   INN   USAN   WHO-DD  
INN   USAN  
Official Name English
sebelipase alfa [INN]
Preferred Name English
SEBELIPASE ALFA [USAN]
Common Name English
CHOLESTEROL ESTER HYDROLASE (HUMAN; AVIAN GLYCOSYLATION)
Common Name English
SEBELIPASE ALFA [JAN]
Common Name English
SEBELIPASE ALFA [MI]
Common Name English
LIPASE A (HUMAN; AVIAN GLYCOSYLATION)
Common Name English
SBC-102
Code English
KANUMA
Brand Name English
HUMAN LYSOSOMAL ACID LIPASE/CHOLESTERYL ESTER HYDROLASE (CHOLESTERYL ESTERASE, LIPASE A, EC=3.1.1.13) GLYCOSYLATED (PRODUCED IN TRANSGENIC GALLUS)
Common Name English
Sebelipase alfa [WHO-DD]
Common Name English
SEBELIPASE ALFA [PURPLE BOOK CDER]
Common Name English
Classification Tree Code System Code
WHO-ATC A16AB14
Created by admin on Mon Mar 31 21:14:10 GMT 2025 , Edited by admin on Mon Mar 31 21:14:10 GMT 2025
FDA ORPHAN DRUG 205805
Created by admin on Mon Mar 31 21:14:10 GMT 2025 , Edited by admin on Mon Mar 31 21:14:10 GMT 2025
NDF-RT N0000192342
Created by admin on Mon Mar 31 21:14:10 GMT 2025 , Edited by admin on Mon Mar 31 21:14:10 GMT 2025
NDF-RT N0000192343
Created by admin on Mon Mar 31 21:14:10 GMT 2025 , Edited by admin on Mon Mar 31 21:14:10 GMT 2025
NCI_THESAURUS C29726
Created by admin on Mon Mar 31 21:14:10 GMT 2025 , Edited by admin on Mon Mar 31 21:14:10 GMT 2025
FDA ORPHAN DRUG 309410
Created by admin on Mon Mar 31 21:14:10 GMT 2025 , Edited by admin on Mon Mar 31 21:14:10 GMT 2025
EU-Orphan Drug EU/3/10/827
Created by admin on Mon Mar 31 21:14:10 GMT 2025 , Edited by admin on Mon Mar 31 21:14:10 GMT 2025
Code System Code Type Description
NDF-RT
N0000192344
Created by admin on Mon Mar 31 21:14:10 GMT 2025 , Edited by admin on Mon Mar 31 21:14:10 GMT 2025
PRIMARY Lysosomal Acid Cholesterol Esterase [Chemical/Ingredient]
DRUG CENTRAL
5028
Created by admin on Mon Mar 31 21:14:10 GMT 2025 , Edited by admin on Mon Mar 31 21:14:10 GMT 2025
PRIMARY
DRUG BANK
DB11563
Created by admin on Mon Mar 31 21:14:10 GMT 2025 , Edited by admin on Mon Mar 31 21:14:10 GMT 2025
PRIMARY
INN
9594
Created by admin on Mon Mar 31 21:14:10 GMT 2025 , Edited by admin on Mon Mar 31 21:14:10 GMT 2025
PRIMARY
DAILYMED
K4YTU42T8G
Created by admin on Mon Mar 31 21:14:10 GMT 2025 , Edited by admin on Mon Mar 31 21:14:10 GMT 2025
PRIMARY
EVMPD
SUB170236
Created by admin on Mon Mar 31 21:14:10 GMT 2025 , Edited by admin on Mon Mar 31 21:14:10 GMT 2025
PRIMARY
SMS_ID
100000159705
Created by admin on Mon Mar 31 21:14:10 GMT 2025 , Edited by admin on Mon Mar 31 21:14:10 GMT 2025
PRIMARY
RXCUI
1726975
Created by admin on Mon Mar 31 21:14:10 GMT 2025 , Edited by admin on Mon Mar 31 21:14:10 GMT 2025
PRIMARY RxNorm
USAN
YY-143
Created by admin on Mon Mar 31 21:14:10 GMT 2025 , Edited by admin on Mon Mar 31 21:14:10 GMT 2025
PRIMARY
EC (ENZYME CLASS)
EC 3.1.1.13
Created by admin on Mon Mar 31 21:14:10 GMT 2025 , Edited by admin on Mon Mar 31 21:14:10 GMT 2025
PRIMARY
MERCK INDEX
m11887
Created by admin on Mon Mar 31 21:14:10 GMT 2025 , Edited by admin on Mon Mar 31 21:14:10 GMT 2025
PRIMARY
ChEMBL
CHEMBL3039537
Created by admin on Mon Mar 31 21:14:10 GMT 2025 , Edited by admin on Mon Mar 31 21:14:10 GMT 2025
PRIMARY
NCI_THESAURUS
C152312
Created by admin on Mon Mar 31 21:14:10 GMT 2025 , Edited by admin on Mon Mar 31 21:14:10 GMT 2025
PRIMARY
FDA UNII
K4YTU42T8G
Created by admin on Mon Mar 31 21:14:10 GMT 2025 , Edited by admin on Mon Mar 31 21:14:10 GMT 2025
PRIMARY
CAS
1276027-63-4
Created by admin on Mon Mar 31 21:14:10 GMT 2025 , Edited by admin on Mon Mar 31 21:14:10 GMT 2025
PRIMARY
Glycosylation Type AVIAN
Glycosylation Link Type Site
N 1_15
N 1_80
N 1_140
N 1_252
N 1_300
Related Record Type Details
Lysosomal acid lipase/cholesteryl ester hydrolase
TARGET->ENZYME REPLACEMENT
Related Record Type Details
SEBELIPASE ALFA
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT CHEMICAL
Molecular Formula CHEMICAL
NIH
NCATS
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