ELOSULFASE ALFA

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Mon Mar 31 21:42:38 GMT 2025` Edited by `admin` on `Mon Mar 31 21:42:38 GMT 2025`
Protein Sub Type
Sequence Type	COMPLETE
Record UNII	ODJ69JZG85
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

RECOMBINANT HUMAN N-ACETYLGALACTOSAMINE-6-SULFATASE (RHGALNS) [EMA EPAR]

Preferred Name

English

ELOSULFASE ALFA

Official Name

English

VIMIZIM

Brand Name

English

CHONDROITIN SULFATASE

Common Name

English

ELOSULFASE ALFA [VANDF]

Common Name

English

CHONDROSULFATASE

Common Name

English

E.C. 3.1.6.4

Common Name

English

RHGALNS

Code

English

ELOSULFASE ALFA [USAN]

Common Name

English

RECOMBINANT HUMAN N-ACETYLGALACTOSAMINE-6-SULFATASE (RHGALNS)

Common Name

English

elosulfase alfa [INN]

Common Name

English

ELOSULFASE ALFA [PURPLE BOOK CDER]

Common Name

English

CHONDROITINASE

Common Name

English

ELOSULFASE ALFA [JAN]

Common Name

English

RECOMBINANT HUMAN N-ACETYLGALACTOSAMINE-6-SULFATASE

Common Name

English

BMN-110

Code

English

HUMAN N-ACETYLGALACTOSAMINE-6-SULFATASE (CHONDROITINSULFATASE, GALACTOSE-6-SULFATE SULFATASE, EC=3.1.6.4) DIMER (139-139`)-DISULFIDE GLYCOSYLATED (PRODUCED BY CHO CELLS)

Common Name

English

Elosulfase alfa [WHO-DD]

Common Name

English

BMN 110

Code

English

ELOSULFASE ALFA [MI]

Common Name

English

Classification Tree Code System Code

FDA ORPHAN DRUG

87794

Created by admin on Mon Mar 31 21:42:38 GMT 2025 , Edited by admin on Mon Mar 31 21:42:38 GMT 2025

FDA ORPHAN DRUG

280809

Created by admin on Mon Mar 31 21:42:38 GMT 2025 , Edited by admin on Mon Mar 31 21:42:38 GMT 2025

EU-Orphan Drug

EU/3/09/657

Created by admin on Mon Mar 31 21:42:38 GMT 2025 , Edited by admin on Mon Mar 31 21:42:38 GMT 2025

NDF-RT

N0000175823

Created by admin on Mon Mar 31 21:42:38 GMT 2025 , Edited by admin on Mon Mar 31 21:42:38 GMT 2025

WHO-ATC

A16AB12

Created by admin on Mon Mar 31 21:42:38 GMT 2025 , Edited by admin on Mon Mar 31 21:42:38 GMT 2025

EMA ASSESSMENT REPORTS

ELOSULFASE ALFA (AUTHOURIZED: MUCOPOLYSACCHARIDOSIS IV)

Created by admin on Mon Mar 31 21:42:38 GMT 2025 , Edited by admin on Mon Mar 31 21:42:38 GMT 2025

Code System Code Type Description

NCI_THESAURUS

C174795

Created by admin on Mon Mar 31 21:42:38 GMT 2025 , Edited by admin on Mon Mar 31 21:42:38 GMT 2025

PRIMARY

SMS_ID

100000156646

Created by admin on Mon Mar 31 21:42:38 GMT 2025 , Edited by admin on Mon Mar 31 21:42:38 GMT 2025

PRIMARY

INN

9686

Created by admin on Mon Mar 31 21:42:38 GMT 2025 , Edited by admin on Mon Mar 31 21:42:38 GMT 2025

PRIMARY

EVMPD

SUB129547

Created by admin on Mon Mar 31 21:42:38 GMT 2025 , Edited by admin on Mon Mar 31 21:42:38 GMT 2025

ALTERNATIVE

RXCUI

1489914

Created by admin on Mon Mar 31 21:42:38 GMT 2025 , Edited by admin on Mon Mar 31 21:42:38 GMT 2025

PRIMARY

RxNorm

ChEMBL

CHEMBL2108676

Created by admin on Mon Mar 31 21:42:38 GMT 2025 , Edited by admin on Mon Mar 31 21:42:38 GMT 2025

PRIMARY

MERCK INDEX

m11740

Created by admin on Mon Mar 31 21:42:38 GMT 2025 , Edited by admin on Mon Mar 31 21:42:38 GMT 2025

PRIMARY

CAS

9025-60-9

Created by admin on Mon Mar 31 21:42:38 GMT 2025 , Edited by admin on Mon Mar 31 21:42:38 GMT 2025

PRIMARY

DRUG BANK

DB09051

Created by admin on Mon Mar 31 21:42:38 GMT 2025 , Edited by admin on Mon Mar 31 21:42:38 GMT 2025

PRIMARY

EVMPD

SUB130626

Created by admin on Mon Mar 31 21:42:38 GMT 2025 , Edited by admin on Mon Mar 31 21:42:38 GMT 2025

PRIMARY

FDA UNII

ODJ69JZG85

Created by admin on Mon Mar 31 21:42:38 GMT 2025 , Edited by admin on Mon Mar 31 21:42:38 GMT 2025

PRIMARY

DAILYMED

ODJ69JZG85

Created by admin on Mon Mar 31 21:42:38 GMT 2025 , Edited by admin on Mon Mar 31 21:42:38 GMT 2025

PRIMARY

WIKIPEDIA

Elosulfase alfa

Created by admin on Mon Mar 31 21:42:38 GMT 2025 , Edited by admin on Mon Mar 31 21:42:38 GMT 2025

PRIMARY

USAN

YY-129

Created by admin on Mon Mar 31 21:42:38 GMT 2025 , Edited by admin on Mon Mar 31 21:42:38 GMT 2025

PRIMARY

IUPHAR

7392

Created by admin on Mon Mar 31 21:42:38 GMT 2025 , Edited by admin on Mon Mar 31 21:42:38 GMT 2025

PRIMARY

DRUG CENTRAL

4999

Created by admin on Mon Mar 31 21:42:38 GMT 2025 , Edited by admin on Mon Mar 31 21:42:38 GMT 2025

PRIMARY

From	To
1_139	2_139
1_282	1_393
2_282	2_393
1_463	1_492
2_463	2_492
1_475	1_481
2_475	2_481

Glycosylation Link Type	Site
N	1_178
N	1_397
N	2_178
N	2_397

Related Record Type Details


					ODJ69JZG85

ELOSULFASE ALFA

ACTIVE MOIETY

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID SUBSTITUTION	[1_53] [2_53]		C		3-OXO-ALANINE	3LXS1M9IE5

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:ESTIMATED	CHEMICAL
Molecular Formula	CHEMICAL