U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

2015
472
Substance Class Protein
Created
by admin
on Mon Mar 31 20:43:56 GMT 2025
Edited
by admin
on Mon Mar 31 20:43:56 GMT 2025
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG1
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
4Z63YK6E0E
Record Status Validated (UNII)
Record Version
  • Download
Related Record Type
Name Type Language
DARATUMUMAB
DASH   INN   USAN   WHO-DD  
INN   USAN  
Official Name English
DARZALEX
Preferred Name English
DARATUMUMAB [PURPLE BOOK CDER]
Common Name English
HUMAX-CD38
Code English
IMMUNOGLOBULIN G1, ANTI-(HUMAN CD38 (ANTIGEN)) (HUMAN MONOCLONAL 3003-005 HEAVY CHAIN), DISULFIDE WITH HUMAN MONOCLONAL 3003-005 .KAPPA.-CHAIN, DIMER
Common Name English
daratumumab [INN]
Common Name English
DARATUMUMAB [MI]
Common Name English
DARATUMUMAB [JAN]
Common Name English
DARATUMUMAB [USAN]
Common Name English
Daratumumab [WHO-DD]
Common Name English
HUMAXCD38
Code English
3003-005
Code English
Classification Tree Code System Code
FDA ORPHAN DRUG 496815
Created by admin on Mon Mar 31 20:43:57 GMT 2025 , Edited by admin on Mon Mar 31 20:43:57 GMT 2025
EU-Orphan Drug EU/3/13/1153
Created by admin on Mon Mar 31 20:43:57 GMT 2025 , Edited by admin on Mon Mar 31 20:43:57 GMT 2025
FDA ORPHAN DRUG 487415
Created by admin on Mon Mar 31 20:43:57 GMT 2025 , Edited by admin on Mon Mar 31 20:43:57 GMT 2025
FDA ORPHAN DRUG 488615
Created by admin on Mon Mar 31 20:43:57 GMT 2025 , Edited by admin on Mon Mar 31 20:43:57 GMT 2025
FDA ORPHAN DRUG 397113
Created by admin on Mon Mar 31 20:43:57 GMT 2025 , Edited by admin on Mon Mar 31 20:43:57 GMT 2025
EMA ASSESSMENT REPORTS DARZALEX (AUTHORIZED: MULTIPLE MYELOMA)
Created by admin on Mon Mar 31 20:43:57 GMT 2025 , Edited by admin on Mon Mar 31 20:43:57 GMT 2025
FDA ORPHAN DRUG 769220
Created by admin on Mon Mar 31 20:43:57 GMT 2025 , Edited by admin on Mon Mar 31 20:43:57 GMT 2025
NCI_THESAURUS C155321
Created by admin on Mon Mar 31 20:43:57 GMT 2025 , Edited by admin on Mon Mar 31 20:43:57 GMT 2025
NCI_THESAURUS C129822
Created by admin on Mon Mar 31 20:43:57 GMT 2025 , Edited by admin on Mon Mar 31 20:43:57 GMT 2025
NDF-RT N0000192336
Created by admin on Mon Mar 31 20:43:57 GMT 2025 , Edited by admin on Mon Mar 31 20:43:57 GMT 2025
FDA ORPHAN DRUG 536216
Created by admin on Mon Mar 31 20:43:57 GMT 2025 , Edited by admin on Mon Mar 31 20:43:57 GMT 2025
WHO-ATC L01XC24
Created by admin on Mon Mar 31 20:43:57 GMT 2025 , Edited by admin on Mon Mar 31 20:43:57 GMT 2025
Code System Code Type Description
NCI_THESAURUS
C74007
Created by admin on Mon Mar 31 20:43:56 GMT 2025 , Edited by admin on Mon Mar 31 20:43:56 GMT 2025
PRIMARY
ChEMBL
CHEMBL2109269
Created by admin on Mon Mar 31 20:43:57 GMT 2025 , Edited by admin on Mon Mar 31 20:43:57 GMT 2025
PRIMARY
WIKIPEDIA
DARATUMUMAB
Created by admin on Mon Mar 31 20:43:57 GMT 2025 , Edited by admin on Mon Mar 31 20:43:57 GMT 2025
PRIMARY
DRUG BANK
DB09331
Created by admin on Mon Mar 31 20:43:57 GMT 2025 , Edited by admin on Mon Mar 31 20:43:57 GMT 2025
PRIMARY
FDA UNII
4Z63YK6E0E
Created by admin on Mon Mar 31 20:43:57 GMT 2025 , Edited by admin on Mon Mar 31 20:43:57 GMT 2025
PRIMARY
CAS
945721-28-8
Created by admin on Mon Mar 31 20:43:56 GMT 2025 , Edited by admin on Mon Mar 31 20:43:56 GMT 2025
PRIMARY
SMS_ID
100000162382
Created by admin on Mon Mar 31 20:43:57 GMT 2025 , Edited by admin on Mon Mar 31 20:43:57 GMT 2025
PRIMARY
RXCUI
1721947
Created by admin on Mon Mar 31 20:43:57 GMT 2025 , Edited by admin on Mon Mar 31 20:43:57 GMT 2025
PRIMARY RxNorm
LACTMED
Daratumumab
Created by admin on Mon Mar 31 20:43:57 GMT 2025 , Edited by admin on Mon Mar 31 20:43:57 GMT 2025
PRIMARY
USAN
AB-73
Created by admin on Mon Mar 31 20:43:57 GMT 2025 , Edited by admin on Mon Mar 31 20:43:57 GMT 2025
PRIMARY
EVMPD
SUB175772
Created by admin on Mon Mar 31 20:43:57 GMT 2025 , Edited by admin on Mon Mar 31 20:43:57 GMT 2025
PRIMARY
DRUG CENTRAL
5063
Created by admin on Mon Mar 31 20:43:57 GMT 2025 , Edited by admin on Mon Mar 31 20:43:57 GMT 2025
PRIMARY
MERCK INDEX
m11896
Created by admin on Mon Mar 31 20:43:57 GMT 2025 , Edited by admin on Mon Mar 31 20:43:57 GMT 2025
PRIMARY
ChEMBL
CHEMBL1743007
Created by admin on Mon Mar 31 20:43:57 GMT 2025 , Edited by admin on Mon Mar 31 20:43:57 GMT 2025
PRIMARY
DAILYMED
4Z63YK6E0E
Created by admin on Mon Mar 31 20:43:57 GMT 2025 , Edited by admin on Mon Mar 31 20:43:57 GMT 2025
PRIMARY
NDF-RT
N0000192335
Created by admin on Mon Mar 31 20:43:57 GMT 2025 , Edited by admin on Mon Mar 31 20:43:57 GMT 2025
PRIMARY CD38-directed Antibody Interactions [MoA]
INN
9128
Created by admin on Mon Mar 31 20:43:57 GMT 2025 , Edited by admin on Mon Mar 31 20:43:57 GMT 2025
PRIMARY
From To
1_22 1_96
1_149 1_205
1_266 1_326
1_372 1_430
2_22 2_96
2_149 2_205
2_266 2_326
2_372 2_430
3_23 3_88
3_134 3_194
4_23 4_88
4_134 4_194
1_225 3_214
2_225 4_214
1_231 2_231
1_234 2_234
Glycosylation Link Type Site
N 1_302
N 2_302
Related Record Type Details
DARATUMUMAB-DFO ZR-89
LABELED -> NON-LABELED
ADP-RIBOSYL CYCLASE/CYCLIC ADP-RIBOSE HYDROLASE 1
TARGET -> INHIBITOR
DARATUMUMAB-DFO ZR-89
CONJUGATE -> PARENT
DARATUMUMAB-FIHJ
SUB_CONCEPT->SUBSTANCE
Related Record Type Details
DARATUMUMAB
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL
NIH
NCATS
PRIVACY NOTICE
ACCESSIBILITY
DISCLAIMER
HHS VULNERABILITY DISCLOSURE
For language access assistance, contact the NCATS Public Information Officer
National Center for Advancing Translational Sciences (NCATS),
6701 Democracy Boulevard, Bethesda MD 20892-4874 • 301-594-8966