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Search results for "ATC|DERMATOLOGICALS" in comments (approximate match)
Status:
US Previously Marketed
Source:
Silver Oxide U.S.P.
(1921)
Source URL:
First marketed in 1921
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Conditions:
Silver iodide is an inorganic compound with the formula AgI. It is used as a photosensitive agent in photography, as a local antiseptic, as a chemical intermediate, and in cloud seeding for rain-making. The major hazards encountered in the use and handling of silver iodide stem from its toxicologic properties. Effects from exposure may include skin rashes, conjunctivitis, argyria (a permanent ashen-gray discoloration of skin, conjunctiva, and internal organs), headache, fever, hypersensitivity, laryngitis, and bronchitis.
Status:
US Previously Marketed
Source:
Corrosive Mercuric Chloride U.S.P.
(1921)
Source URL:
First marketed in 1921
Source:
Corrosive Mercuric Chloride U.S.P.
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Potassium Triiodomercurate(II) is a periodometallate salt. It contains a triiodomercurate(1-). It is an antiseptic (topical) and disinfectant. It is also an antiseborrheic agent.
Status:
US Previously Marketed
Source:
Corrosive Mercuric Chloride U.S.P.
(1921)
Source URL:
First marketed in 1921
Source:
Corrosive Mercuric Chloride U.S.P.
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Potassium Triiodomercurate(II) is a periodometallate salt. It contains a triiodomercurate(1-). It is an antiseptic (topical) and disinfectant. It is also an antiseborrheic agent.
Status:
US Previously Marketed
Source:
Potassium Permanganate U.S.P.
(1921)
Source URL:
First marketed in 1921
Source:
Potassium Permanganate U.S.P.
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Sodium permanganate is the inorganic compound used as oxidant and etchant in printed circuitry. Sodium permanganate is a purplish-colored, inorganic salt compound, which is primarily available in aqueous form as a monohydrate. It is miscible in water, ether, ethanol, and liquid chlorine. Sodium permanganate offers a high concentration of permanganate ions. Owing to high solubility in water, it is used for etching of plastic parts, as etching requires a high concentration of permanganate ions. Sodium permanganate is also used for water treatment and soil treatment, as it is capable of degrading phenols, BTEX, chlorinated ethenes, and PAHS and removing hydrogen sulfide.
Status:
US Previously Marketed
Source:
Corrosive Mercuric Chloride U.S.P.
(1921)
Source URL:
First marketed in 1921
Source:
Corrosive Mercuric Chloride U.S.P.
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Potassium Triiodomercurate(II) is a periodometallate salt. It contains a triiodomercurate(1-). It is an antiseptic (topical) and disinfectant. It is also an antiseborrheic agent.
Status:
US Previously Marketed
First marketed in 1919
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Conditions:
Acriflavine (ACF) is a topical antiseptic. The hydrochloride form is more irritating than the neutral form. It is derived from acridine. Commercial preparations are often mixtures with proflavine. Acriflavine was developed in 1912 by Paul Ehrlich, a German medical researcher, and was used during the First World War against sleeping sickness. ACF has known trypanocidal, antibacterial, and antiviral activities. Effects of ACF on cancer cells were first reported 50 years ago. By present time was demonstrated that ACF a drug, that binds directly to HIF-1 alpha and HIF-2 alpha and inhibits HIF-1 dimerization and transcriptional activity and thus has potent inhibitory effects on tumor growth and vascularization. Also Acriflavine in combination with 3,6-diaminoacridine (proflavine) could prove to be a potential antimalarial drug and its pharmacological action can be due to inhibition of gyrase activity. This is achieved through interaction of the ACF with the DNA substrate. This interaction may lead to conformation change in DNA unsuitable for binding of gyrase with DNA.
Status:
US Previously Marketed
Source:
ACTILAMIDE CHLORAMINE T by BROEMMEL
(1961)
Source URL:
First marketed in 1916
Source:
Chloramine-T by Dakin
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
Tosylchloramide or N-chloro tosylamide, sodium salt, sold as chloramine-T, is an investigational animal drug used in the aquaculture industry and also is a very effective odor control compound. It has other applications that include: algaecide, bactericide, germicide, parasite control, and for drinking water disinfection. It is also highly effective against bacteria, viruses, and spores.
In the aquaculture and aquafarming industries, Chloramine -T (Tosylchloramide Sodium Salt) is used to treat external bacterial infections in salmonid fish such as koi, salmon, trout, and whitefish. In the personal care industry, it is used in hydrotherapy treatments to revitalize, maintain, and restore health.
Hydrotherapeutic applications include whirlpools, saunas, steam baths, foot baths, and sitz baths. Chloramine-T is also used for disinfection in saunas, solariums, gyms, sport centres, kitchens, sanitary facilities, and air conditioning units. As an anti-microbial agent,Chloramine-T (Tosylchloramide Sodium Salt) it has had widespread use in a broad range of practices, including medical, dental, verterinary food processing and agricultural. It also has been used in direct contact with tissues because it has a low degree of cytotoxicity. Within the United States of America, the use of Chloramine-T is more restricted. Disifin (Tosylchloramide) destroys DNA and thereby prevents microbes from. DISIFIN® Tablets are effective against a whole series of microorganisms, including grampositive and gram-negative bacteria,
enveloped and non-en reproducing.
Status:
Possibly Marketed Outside US
Source:
RIVANOL by Roser|Jensch
Source URL:
First approved in 2015
Source:
B Vial by Prodibio SAS
Source URL:
Class (Stereo):
CHEMICAL (RACEMIC)
Conditions:
Ethacridine (Rivanol) is an acridine derivative indicated for the treatment of bacterial infections. In many countries the drug was in clinical practice for the second trimester termination of pregnancy.
Status:
Possibly Marketed Outside US
First approved in 1999
Source:
21 CFR 358H
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
Cetrimide is a quaternary ammonium compound. Cetrimide was first introduced as a combined cleanser and skin antiseptic by Barnes (1942). Cetrimide combines excellent detergent properties and minimal toxicity with a useful antiseptic action. Cetrimide affects membrane permeability allowing ‘leaking’ of essential cell constituents leading to cell death. This medication is a skin antiseptic and disinfectant prescribed for seborrhoeic dermatitis and wound cleansing. The cream has a bactericidal activity against gram-positive bacteria and incompatible with soaps and other anionic surfactants.
Status:
Possibly Marketed Outside US
Source:
NCT01950247: Phase 4 Interventional Unknown status Iron Deficiency Anemia (IDA)
(2013)
Source URL:
First approved in 1996
Source:
NDA021262
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Sodium chlorite (NaClO2), a sodium salt of chlorite ion, is used as a disinfectant in water treatment and as a component in therapeutic rinses and gels. NaClO2 is an active ingredient of veterinary solution AZTEC GOLD, which is used to reduce the spread of organisms, which may cause mastitis in cows. NaClO2 can increase production of reactive oxygen species, which cause the oxidative stress in human erythrocytes, and as a result, the res cell senescence.