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Details

Stereochemistry RACEMIC
Molecular Formula C15H15N3O.C3H6O3.H2O
Molecular Weight 361.3923
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ETHACRIDINE LACTATE

SMILES

O.CC(O)C(O)=O.CCOC1=CC2=C(C=C1)N=C3C=C(N)C=CC3=C2N

InChI

InChIKey=NYEPHMYJRNWPLA-UHFFFAOYSA-N
InChI=1S/C15H15N3O.C3H6O3.H2O/c1-2-19-10-4-6-13-12(8-10)15(17)11-5-3-9(16)7-14(11)18-13;1-2(4)3(5)6;/h3-8H,2,16H2,1H3,(H2,17,18);2,4H,1H3,(H,5,6);1H2

HIDE SMILES / InChI

Description

Ethacridine (Rivanol) is an acridine derivative indicated for the treatment of bacterial infections. In many countries the drug was in clinical practice for the second trimester termination of pregnancy.

Originator

Roser|Jensch
3

Approval Year

2015
471

Conditions

ConditionModalityTargetsHighest PhaseProduct
Bacterial infections
234
 Curative
Approved
8,429
RIVANOL

Doses

PubMed

Patents

JPH1043211A
6
JPS5519215A
9
JPS58192830A
3
JPS6040139A
3

Sample Use Guides

In Vivo Use Guide
Apply 0,1 % cutaneous solution to the affected area of skin.
Route of Administration: Topical
In Vitro Use Guide
Ethacridine shows weak becteriostatic activity against gram-positive bacteria with MIC 1-10 ug/ml.
ACTIVE MOIETY
Structure of ETHACRIDINE
SUBSTANCE RECORD
Structure of ETHACRIDINE LACTATE
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