ETHACRIDINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C15H15N3O
Molecular Weight	253.2991
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

SMILES

CCOC1=CC2=C(N)C3=CC=C(N)C=C3N=C2C=C1

InChI

InChIKey=CIKWKGFPFXJVGW-UHFFFAOYSA-N

InChI=1S/C15H15N3O/c1-2-19-10-4-6-13-12(8-10)15(17)11-5-3-9(16)7-14(11)18-13/h3-8H,2,16H2,1H3,(H2,17,18)

HIDE SMILES / InChI

Molecular Formula	C15H15N3O
Molecular Weight	253.2991
Charge	0
Count	MOL RATIO 1 MOL RATIO (average)

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description

Ethacridine (Rivanol) is an acridine derivative indicated for the treatment of bacterial infections. In many countries the drug was in clinical practice for the second trimester termination of pregnancy.

Originator

Approval Year

Conditions

Conditions

Condition	Modality	Targets	Highest Phase	Product
Bacterial infections 235	Curative		Approved 8,583	RIVANOL

Doses

Doses

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Dose	Population	Adverse events
200 mL single, intrauterine Recommended	pregnant, ADULT

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PubMed

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Title	Date	PubMed
Method for non-invasively recording electrocardiograms in conscious mice.	2001	11476671
Identification of lactate. Analytical methods of pharmacopoeias with DBH in respect to environmental and economical concern, Part 4.	2001 Jul	11487973
Reconstruction of benzene exposure for the Pliofilm cohort (1936-1976) using Monte Carlo techniques.	2003 Apr 25	12746133
Reports of head injury and symptom knowledge among college athletes: implications for assessment and educational intervention.	2003 Jul	12855923
[Spectral analysis of the electrical activity of the left colon].	2004 Jul-Sep	15678202

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Patents

Sample Use Guides

In Vivo Use Guide

Apply 0,1 % cutaneous solution to the affected area of skin.

Route of Administration: Topical

In Vitro Use Guide

Ethacridine shows weak becteriostatic activity against gram-positive bacteria with MIC 1-10 ug/ml.

Substance Class	Chemical
Record UNII	WIX85M1A6R
Record Status	`Validated (UNII)`
Record Version

Show entries

Name

Type

Language

ETHACRIDINE

Official Name

English

OPHOSEPT

Preferred Name

English

6,9-DIAMINO-2-ETHOXYACRIDINE

Systematic Name

English

ETHACRIDINE [MI]

Common Name

English

NSC-163296

Code

English

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Code System

Code

Type

Description

DRUG CENTRAL

3194

PRIMARY

MERCK INDEX

m5041

PRIMARY

Merck Index

PUBCHEM

2017

PRIMARY

ChEMBL

CHEMBL94007

PRIMARY

DAILYMED

WIX85M1A6R

PRIMARY

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Related Record

Type

Details


					WIX85M1A6R

ETHACRIDINE

ACTIVE MOIETY

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