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Showing 1 - 10 of 40 results

Status:
US Approved Rx (1969)
First approved in 1948

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

Mafenide is a sulfonamide-type medication used as an antibiotic. It is indicated for use as an adjunctive topical antimicrobial agent to control bacterial infection when used under moist dressings over meshed autografts on excised burn wounds. Mafeni...
Status:
US Approved OTC
First marketed in 1895

Class (Stereo):
CHEMICAL (ACHIRAL)



Benzocaine is a local anesthetic. It acts by blocking voltage-gated sodium ion channels in nerve endings. Benzocaine is available over-the counter for local anesthesia of oral and pharyngeal mucous membranes (sore throat, cold sores, mouth ulcers, to...
Status:
US Previously Marketed
First approved in 1971

Class (Stereo):
CHEMICAL (ABSOLUTE)



Histidine is an essential amino acid. L-histidine is converted to histamine by histidine decarboxylase, a pyridoxal 5'-phosphate-dependent enzyme. The copper(II)–l-histidine (1:2 complex at physiological pH) has been widely used in the treatment of M...
Status:
US Previously Marketed
First marketed in 1924

Class (Stereo):
CHEMICAL (RACEMIC)


Merbromin (marketed as Mercurochrome, Merbromine) is a topical antiseptic used for minor cuts and scrapes. It is readily available in most countries but, because of its mercury content, it is no longer sold in Switzerland, France, Germany, and the Un...
Status:
US Previously Marketed
First marketed in 1921

Class (Stereo):
CHEMICAL (ACHIRAL)



Silver iodide is an inorganic compound with the formula AgI. It is used as a photosensitive agent in photography, as a local antiseptic, as a chemical intermediate, and in cloud seeding for rain-making. The major hazards encountered in the use and ha...
Status:
Possibly Marketed Outside US
First approved in 2020

Class (Stereo):
CHEMICAL (ABSOLUTE)



Betulin is an extract from bark of the white birch tree, which has been known since the 18th century and is chemically defined. Betulin was discovered by German-Russian chemist Johann Tobias Lowitz. He was the first scientist to study and characteris...
Status:
Possibly Marketed Outside US
First approved in 2014

Class (Stereo):
CHEMICAL (ABSOLUTE)



Madecassic acid is a naturally produced terpene from Centella asiatica. It has demonstrated anti-inflammatory and anti-diabetic effects by blocking NF-kB activation and altering lipid metabolism in mice. Madecassic acid has also shown anti-tumor effe...
Status:
Possibly Marketed Outside US
First approved in 2012

Class (Stereo):
CHEMICAL (ABSOLUTE)



Madecassoside is a triterpenoid compound found in Centella asiatica (Gotu kola), a medicinal herb used in traditional Chinese medicine (TCM), Ayurvedic medicine, and traditional African medicine. Madecassoside has a wide range of reported biological ...
Status:
Possibly Marketed Outside US
First approved in 2011

Class (Stereo):
CHEMICAL (ACHIRAL)



Stearic monoethanolamide (widely known as N-stearoylethanolamine, NSE) is a biologically active cell membrane component with anti-inflammatory and membrane-protective properties. Preliminary data from a model of experimental burn in rats have shown t...
Status:
Possibly Marketed Outside US
First approved in 1962

Class (Stereo):
CHEMICAL (ACHIRAL)


Biebrich scarlet red (scarlet red) an azo dye that has been used to impart color to pharmaceutic preparations. The color produced by the longest waves of the visible spectrum, approximately 630 to 750 nm. In combination with phenol it’s used in veter...