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Details

Stereochemistry ACHIRAL
Molecular Formula Ag
Molecular Weight 107.8682
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 1

SHOW SMILES / InChI
Structure of SILVER CATION

SMILES

[Ag+]

InChI

InChIKey=FOIXSVOLVBLSDH-UHFFFAOYSA-N
InChI=1S/Ag/q+1

HIDE SMILES / InChI

Molecular Formula Ag
Molecular Weight 107.8682
Charge 1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description
Curator's Comment: description was created based on several sources, including https://www.drugs.com/monograph/silver-nitrate.html | https://www.ncbi.nlm.nih.gov/pubmed/18245232

Silver iodide is an inorganic compound with the formula AgI. It is used as a photosensitive agent in photography, as a local antiseptic, as a chemical intermediate, and in cloud seeding for rain-making. The major hazards encountered in the use and handling of silver iodide stem from its toxicologic properties. Effects from exposure may include skin rashes, conjunctivitis, argyria (a permanent ashen-gray discoloration of skin, conjunctiva, and internal organs), headache, fever, hypersensitivity, laryngitis, and bronchitis.

Originator

Sources: Vestsi Akademii Navuk BSSR, Seryya Khimichnykh Navuk, Issue 2, Pages 69-73, Journal, 1990https://www.ncbi.nlm.nih.gov/pubmed/20429870
Curator's Comment: The medical uses of silver date back to at least the time of Hippocrates

Approval Year

TargetsConditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Advantage Arrest Silver Diamine Fluoride

Approved Use

Unknown
Primary
Advantage Arrest Silver Diamine Fluoride

Approved Use

Unknown
Primary
Unknown

Approved Use

Unknown
Curative
Unknown

Approved Use

Unknown
Curative
Unknown

Approved Use

Unknown
Primary
Colloidal silver iodide

Approved Use

Solution containing 5 to 49% of colloidal silver iodide have been employed in the treatment of infections of the mucous membranes. Ointments, usually containing 5%, have been used in inflammatory conditions of the eye, ear, and nose.
Primary
Colloidal silver iodide

Approved Use

Solution containing 5 to 49% of colloidal silver iodide have been employed in the treatment of infections of the mucous membranes. Ointments, usually containing 5%, have been used in inflammatory conditions of the eye, ear, and nose.
Palliative
Unknown

Approved Use

Antiseptic Wound Cauterization
Primary
Unknown

Approved Use

Prophylaxis of gonococcal ophthalmia neonatorum. AAP recommends use of topical silver nitrate, povidone-iodine, or possibly erythromycin for prophylaxis of nongonococcal nonchlamydial conjunctivitis in neonates, ideally administered shortly after birth.
PubMed

PubMed

TitleDatePubMed
Comparative efficacy of hand hygiene agents in the reduction of bacteria and viruses.
2005 Mar
Antibacterial activity and mechanism of action of the silver ion in Staphylococcus aureus and Escherichia coli.
2008 Apr
Development of silica-coated silver iodide nanoparticles and their biodistribution.
2012 Dec
Directional growth of Ag nanorod from polymeric silver cyanide: A potential substrate for concentration dependent SERS signal enhancement leading to melamine detection.
2017 Aug 5
Patents

Sample Use Guides

In Vivo Use Guide
Curator's Comment: Toxicity data
Topical as a 1:80 dilution (30 ppm ionic silver).
Route of Administration: Topical
10 mkl volume of undiluted human norovirus 20% faecal suspension was mixed with 90 mkl of SDC (Silver Dihydrogen Citrate) for various contact times (15, 30, 60, 120, 300, 600 and 1800 s). At each sampling time point, 20 mkl of this solution was added to 180 mkl of 10% solution of Dey/Engley (D/E) neutralizing broth (Thermo Fisher Scientific, Waltham, MA). Samples were aliquoted and frozen at -80°C prior to nucleic acid extraction.
Substance Class Chemical
Created
by admin
on Fri Dec 15 17:17:47 UTC 2023
Edited
by admin
on Fri Dec 15 17:17:47 UTC 2023
Record UNII
57N7B0K90A
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
SILVER CATION
Common Name English
SILVER, ION (AG1+)
Common Name English
Classification Tree Code System Code
EPA PESTICIDE CODE 72500
Created by admin on Fri Dec 15 17:17:47 UTC 2023 , Edited by admin on Fri Dec 15 17:17:47 UTC 2023
Code System Code Type Description
FDA UNII
57N7B0K90A
Created by admin on Fri Dec 15 17:17:47 UTC 2023 , Edited by admin on Fri Dec 15 17:17:47 UTC 2023
PRIMARY
DRUG BANK
DB14521
Created by admin on Fri Dec 15 17:17:47 UTC 2023 , Edited by admin on Fri Dec 15 17:17:47 UTC 2023
PRIMARY
CAS
14701-21-4
Created by admin on Fri Dec 15 17:17:47 UTC 2023 , Edited by admin on Fri Dec 15 17:17:47 UTC 2023
PRIMARY
RXCUI
1358876
Created by admin on Fri Dec 15 17:17:47 UTC 2023 , Edited by admin on Fri Dec 15 17:17:47 UTC 2023
PRIMARY RxNorm
DAILYMED
57N7B0K90A
Created by admin on Fri Dec 15 17:17:47 UTC 2023 , Edited by admin on Fri Dec 15 17:17:47 UTC 2023
PRIMARY
EPA CompTox
DTXSID10892099
Created by admin on Fri Dec 15 17:17:47 UTC 2023 , Edited by admin on Fri Dec 15 17:17:47 UTC 2023
PRIMARY
PUBCHEM
104755
Created by admin on Fri Dec 15 17:17:47 UTC 2023 , Edited by admin on Fri Dec 15 17:17:47 UTC 2023
PRIMARY
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