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Details

Stereochemistry ACHIRAL
Molecular Formula C19H42N.Br
Molecular Weight 364.447
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CETRIMONIUM BROMIDE

SMILES

[Br-].CCCCCCCCCCCCCCCC[N+](C)(C)C

InChI

InChIKey=LZZYPRNAOMGNLH-UHFFFAOYSA-M
InChI=1S/C19H42N.BrH/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(2,3)4;/h5-19H2,1-4H3;1H/q+1;/p-1

HIDE SMILES / InChI
Molecular Formula BrH
Molecular Weight 80.912
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula C19H42N
Molecular Weight 284.5435
Charge 1
Count
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description
Curator's Comment: Description was created based on several sources, including http://www.americanpharmaceuticalreview.com/Featured-Articles/38886-Antimicrobial-Preservatives-Part-One-Choosing-a-Preservative-System/ | https://books.google.ru/books?id=EMrSBwAAQBAJ&printsec=frontcover&hl=ru#v=onepage&q&f=false | https://www.ncbi.nlm.nih.gov/pubmed/9880479 | http://www.medindia.net/doctors/drug_information/cetrimide.htm

Cetrimide is a quaternary ammonium compound. Cetrimide was first introduced as a combined cleanser and skin antiseptic by Barnes (1942). Cetrimide combines excellent detergent properties and minimal toxicity with a useful antiseptic action. Cetrimide affects membrane permeability allowing ‘leaking’ of essential cell constituents leading to cell death. This medication is a skin antiseptic and disinfectant prescribed for seborrhoeic dermatitis and wound cleansing. The cream has a bactericidal activity against gram-positive bacteria and incompatible with soaps and other anionic surfactants.

Originator

Imperial Chemical Industries
59
Curator's Comment: Cetrimide was first introduced as a combined cleanser and skin antiseptic by Barnes (1942). http://www.sciencedirect.com/science/article/pii/S0140673600701000 reference retrieved from https://www.ncbi.nlm.nih.gov/pubmed/18132350

Approval Year

1999
174
Targets

Targets

Primary TargetPharmacologyConditionPotency
Inhibitor
8297
Interacts
323
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Curative
Approved
8429
CETRIMIDE

Approved Use

Cetrimide is a skin antiseptic and disinfectant prescribed for seborrhoeic dermatitis and wound cleansing. The cream has a bactericidal activity against gram-positive bacteria and incompatible with soaps and other anionic surfactants.
Primary
Approved
8429
CETRIMIDE

Approved Use

Cetrimide is a skin antiseptic and disinfectant prescribed for seborrhoeic dermatitis and wound cleansing. The cream has a bactericidal activity against gram-positive bacteria and incompatible with soaps and other anionic surfactants.
PubMed

PubMed

TitleDatePubMed
The effects of two quaternary ammonium compounds on citric acid and sterol synthesis in Aspergillus niger.
1963 Apr
Antiseptics and disinfectants: activity, action, and resistance.
1999 Jan
Patents

Patents

US6187290B1
9
US6284289B1
9

Sample Use Guides

In Vivo Use Guide
Wound cleansing - Topical : Adult: Apply 0.1-1% aqueous solution or 0.5% cream onto affected area. Seborrhoeic dermatitis - Topical : Adult: Apply 10% shampoo solution onto the scalp.
Route of Administration: Topical
In Vitro Use Guide
Cetrimide, at 30 ug/ml inhibited growth of Aspergillus niger.
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:00:33 GMT 2023
Edited
by admin
on Fri Dec 15 15:00:33 GMT 2023
Record UNII
L64N7M9BWR
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
CETRIMONIUM BROMIDE
INCI   INN   MART.   MI   USP-RS   VANDF   WHO-DD  
INCI   INN  
Official Name English
RONACARE CETRIMONIUM BROMIDE
Brand Name English
CETAB
Common Name English
BROMAT
Brand Name English
CETRIMONIUM BROMIDE [MART.]
Common Name English
CETRIMONIUM BROMIDE [MI]
Common Name English
cetrimonium bromide [INN]
Common Name English
CETYL TRIMETHYL AMMONIUM BROMIDE
Systematic Name English
Cetrimonium bromide [WHO-DD]
Common Name English
CETRIMONIUM BROMIDE [VANDF]
Common Name English
CETYLTRIMETHYLAMMONIUM BROMIDE
Systematic Name English
ACETOQUAT CTAB
Brand Name English
RHODAQUAT M-242B/99
Brand Name English
CETRIMONIUM BROMIDE [USP-RS]
Common Name English
SUMQUAT 6030
Brand Name English
NSC-32927
Code English
N,N,N-TRIMETHYL-1-HEXADECANAMINIUM BROMIDE
Systematic Name English
HEXADECYLTRIMETHYLAMMONIUM BROMIDE
Systematic Name English
CETRIMONIUM BROMIDE [INCI]
Common Name English
Classification Tree Code System Code
EPA PESTICIDE CODE 69117
Created by admin on Fri Dec 15 15:00:33 GMT 2023 , Edited by admin on Fri Dec 15 15:00:33 GMT 2023
NCI_THESAURUS C28394
Created by admin on Fri Dec 15 15:00:33 GMT 2023 , Edited by admin on Fri Dec 15 15:00:33 GMT 2023
WHO-ATC D08AJ04
Created by admin on Fri Dec 15 15:00:33 GMT 2023 , Edited by admin on Fri Dec 15 15:00:33 GMT 2023
WHO-ATC D11AC01
Created by admin on Fri Dec 15 15:00:33 GMT 2023 , Edited by admin on Fri Dec 15 15:00:33 GMT 2023
Code System Code Type Description
CHEBI
3567
Created by admin on Fri Dec 15 15:00:33 GMT 2023 , Edited by admin on Fri Dec 15 15:00:33 GMT 2023
PRIMARY
MESH
C004322
Created by admin on Fri Dec 15 15:00:33 GMT 2023 , Edited by admin on Fri Dec 15 15:00:33 GMT 2023
PRIMARY
NSC
32927
Created by admin on Fri Dec 15 15:00:33 GMT 2023 , Edited by admin on Fri Dec 15 15:00:33 GMT 2023
PRIMARY
EPA CompTox
DTXSID5037028
Created by admin on Fri Dec 15 15:00:33 GMT 2023 , Edited by admin on Fri Dec 15 15:00:33 GMT 2023
PRIMARY
RS_ITEM_NUM
1102974
Created by admin on Fri Dec 15 15:00:33 GMT 2023 , Edited by admin on Fri Dec 15 15:00:33 GMT 2023
PRIMARY
CHEBI
29223
Created by admin on Fri Dec 15 15:00:33 GMT 2023 , Edited by admin on Fri Dec 15 15:00:33 GMT 2023
PRIMARY
DAILYMED
L64N7M9BWR
Created by admin on Fri Dec 15 15:00:33 GMT 2023 , Edited by admin on Fri Dec 15 15:00:33 GMT 2023
PRIMARY
WIKIPEDIA
CETRIMONIUM BROMIDE
Created by admin on Fri Dec 15 15:00:33 GMT 2023 , Edited by admin on Fri Dec 15 15:00:33 GMT 2023
PRIMARY
NCI_THESAURUS
C73149
Created by admin on Fri Dec 15 15:00:33 GMT 2023 , Edited by admin on Fri Dec 15 15:00:33 GMT 2023
PRIMARY
SMS_ID
100000081536
Created by admin on Fri Dec 15 15:00:33 GMT 2023 , Edited by admin on Fri Dec 15 15:00:33 GMT 2023
PRIMARY
RXCUI
288999
Created by admin on Fri Dec 15 15:00:33 GMT 2023 , Edited by admin on Fri Dec 15 15:00:33 GMT 2023
PRIMARY RxNorm
CAS
57-09-0
Created by admin on Fri Dec 15 15:00:33 GMT 2023 , Edited by admin on Fri Dec 15 15:00:33 GMT 2023
PRIMARY
PUBCHEM
5974
Created by admin on Fri Dec 15 15:00:33 GMT 2023 , Edited by admin on Fri Dec 15 15:00:33 GMT 2023
PRIMARY
ChEMBL
CHEMBL1183605
Created by admin on Fri Dec 15 15:00:33 GMT 2023 , Edited by admin on Fri Dec 15 15:00:33 GMT 2023
PRIMARY
ECHA (EC/EINECS)
200-311-3
Created by admin on Fri Dec 15 15:00:33 GMT 2023 , Edited by admin on Fri Dec 15 15:00:33 GMT 2023
PRIMARY
MERCK INDEX
m3294
Created by admin on Fri Dec 15 15:00:33 GMT 2023 , Edited by admin on Fri Dec 15 15:00:33 GMT 2023
PRIMARY Merck Index
DRUG BANK
DBSALT001769
Created by admin on Fri Dec 15 15:00:33 GMT 2023 , Edited by admin on Fri Dec 15 15:00:33 GMT 2023
PRIMARY
INN
2036
Created by admin on Fri Dec 15 15:00:33 GMT 2023 , Edited by admin on Fri Dec 15 15:00:33 GMT 2023
PRIMARY
FDA UNII
L64N7M9BWR
Created by admin on Fri Dec 15 15:00:33 GMT 2023 , Edited by admin on Fri Dec 15 15:00:33 GMT 2023
PRIMARY
EVMPD
SUB07458MIG
Created by admin on Fri Dec 15 15:00:33 GMT 2023 , Edited by admin on Fri Dec 15 15:00:33 GMT 2023
PRIMARY
Related Record Type Details
Structure of CETRIMONIUM
PARENT -> SALT/SOLVATE
Related Record Type Details
Structure of CETRIMONIUM
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