U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 1671 - 1680 of 1709 results

structurally diverse
Status:
US Approved Rx (1999)
Source:
BLA103915
(1999)
Source URL:

Class:
STRUCTURALLY DIVERSE

structurally diverse
Status:
US Approved Rx (2016)
Source:
BLA125596
(2016)
Source URL:
First approved in 1944
Source:
BLA101134
Source URL:

Class:
STRUCTURALLY DIVERSE


Immune globulin human (Human immunoglobulin) is a mixture of IgG1 and other antibodies derived from healthy human plasma and used to strengthen the body's natural defense system (immune system) to reduce the risk of infection in people with weakened immune systems. Human immunoglobulin is used as replacement therapy for inherited humoral immunodeficiency disorders, such as severe combined immunodeficiency syndrome, x-linked agammaglobulinemia, and Wiskott-Aldrich syndrome. Human immunoglobulin interacts with a number of different components of the immune system, including cytokines, complement, Fc receptors, and several immunocompetent cell surface molecules. Human immunoglobulin also acts on various effector cells of the immune system (B and T lymphocytes, dendritic cells, etc.) and regulates a wide range of genes. Human immune globulin competitively blocks gamma Fc receptors, preventing the binding and ingestion of phagocytes and inhibiting platelet depletion. Human immunoglobulin contains a number of different antibodies that prevent infection by attaching pathogenic microorganisms to the surface and facilitating their removal before they can infect cells. Antibodies remove pathogens by activating complement, agglutination or precipitation, blocking the pathogen receptor, “tagging” macrophages, or neutralizing the pathogen toxins. Serious adverse reactions are observed during intravenous treatment in clinical studies of aseptic meningitis. The most common adverse reactions were headache, fatigue, hyperthermia, nausea, chills, severity, pain in the limbs, diarrhea, migraine, dizziness, vomiting, cough, urticaria, asthma, sore throat and throat, rash, myalgia, itching, and cardiac murmur. During clinical trials of subcutaneous treatment, no serious adverse reactions were observed.
structurally diverse
Status:
US Approved Rx (1976)
Source:
BLA102366
(1976)
Source URL:

Class:
STRUCTURALLY DIVERSE

structurally diverse
Status:
US Approved Rx (1997)
Source:
BLAnull
(1997)
Source URL:

Class:
STRUCTURALLY DIVERSE

structurally diverse
Status:
US Approved Rx (1999)
Source:
BLAnull
(1999)
Source URL:

Class:
STRUCTURALLY DIVERSE

structurally diverse
Status:
US Approved Rx (1997)
Source:
BLAnull
(1997)
Source URL:

Class:
STRUCTURALLY DIVERSE

structurally diverse
Status:
US Approved Rx (1997)
Source:
BLAnull
(1997)
Source URL:

Class:
STRUCTURALLY DIVERSE

structurally diverse
Status:
US Approved Rx (1936)
Source:
BLA101062
(1936)
Source URL:
First approved in 1936
Source:
BLA101062
Source URL:

Class:
STRUCTURALLY DIVERSE

structurally diverse
Status:
First approved in 1921
Source:
Olive Oil U.S.P.
Source URL:

Class:
STRUCTURALLY DIVERSE

structurally diverse
Status:
US Approved OTC
Source:
21 CFR 357.210(b) cholecystokinetic soybean oil, hydrogenated (powder)
Source URL:

Class:
STRUCTURALLY DIVERSE

Showing 1671 - 1680 of 1709 results