TOFERSEN

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Name

Type

Language

TOFERSEN

Official Name

English

tofersen [INN]

Common Name

English

BIIB-067

Code

English

TOFERSEN [USAN]

Common Name

English

DNA, D((2'-O-(2-METHOXYETHYL))M5RC-SP-(2'-O-(2-METHOXYETHYL))RA-(2'-O-(2-METHOXYETHYL))RG-SP-(2'-O-(2-METHOXYETHYL))RG-(2'-O-(2-METHOXYETHYL))RA-SP-T-SP-A-SP-M5C-SP-A-SP-T-SP-T-SP-T-SP-M5C-SP-T-SP-A-SP-(2'-O-(2-METHOXYETHYL))M5RC-(2'-O-(2-METHOXYETHYL))R

Systematic Name

English

ALL-P-AMBO-2'-O-(2-METHOXYETHYL)-5-METHYL-P-THIOCYTIDYLYL-(3'->5')-2'-O-(2-METHOXYETHYL)ADENYLYL-(3'->5')-2'-O-(2-METHOXYETHYL)-P-THIOGUANYLYL-(3'->5')-2'-O-(2-METHOXYETHYL)GUANYLYL-(3'->5')-2'-O-(2-METHOXYETHYL)-P-THIOADENYLYL-(3'->5')-P-THIOTHYMIDYLYL-

Systematic Name

English

TOFERSEN [JAN]

Common Name

English

ISIS-SOD1RX

Code

English

BIIB067

Code

English

Classification Tree Code System Code

FDA ORPHAN DRUG

537216

Created by admin on Sat Dec 16 16:59:55 GMT 2023 , Edited by admin on Sat Dec 16 16:59:55 GMT 2023

Code System Code Type Description

USAN

EF-06

Created by admin on Sat Dec 16 16:59:55 GMT 2023 , Edited by admin on Sat Dec 16 16:59:55 GMT 2023

PRIMARY

DRUG BANK

DB14782

Created by admin on Sat Dec 16 16:59:55 GMT 2023 , Edited by admin on Sat Dec 16 16:59:55 GMT 2023

PRIMARY

CAS

2088232-70-4

Created by admin on Sat Dec 16 16:59:55 GMT 2023 , Edited by admin on Sat Dec 16 16:59:55 GMT 2023

PRIMARY

FDA UNII

2NU6F9601K

Created by admin on Sat Dec 16 16:59:55 GMT 2023 , Edited by admin on Sat Dec 16 16:59:55 GMT 2023

PRIMARY

NCI_THESAURUS

C166584

Created by admin on Sat Dec 16 16:59:55 GMT 2023 , Edited by admin on Sat Dec 16 16:59:55 GMT 2023

PRIMARY

INN

10804

Created by admin on Sat Dec 16 16:59:55 GMT 2023 , Edited by admin on Sat Dec 16 16:59:55 GMT 2023

PRIMARY

Sugar	Site Range	Site Count
2'-O-Methoxyethyl ribose	1_1-1_5;1_16-1_19	9 / 20
Deoxyribose (DNA)	1_5-1_15	11 / 20

Linkage	Site Range	Site Count
Phosphate	1_3;1_5;1_17;1_19	4 / 19
Phosporothioate	1_2;1_4;1_6-1_16;1_18;1_20	15 / 19

ACTIVE MOIETY


					2NU6F9601K

TOFERSEN

SALT/SOLVATE (PARENT)


					5YL205692C

TOFERSEN SODIUM