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Showing 1 - 10 of 2,893 results

Status:
US Approved Rx (2019)
First approved in 2002

Class (Stereo):
CHEMICAL (ACHIRAL)



Nitisinone, 2-(2-nitro-4-trifluoromethylbenzoyl)-1,3-cyclohexanedione (NTBC) is a triketone with herbicidal activity. Orfadin® capsules contain nitisinone used in the treatment of hereditary tyrosinemia type 1 (HT-1). Nitisinone is a competitive inhi...
Status:
US Approved Rx (2002)
First approved in 2002

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

Sodium oxybate is the sodium salt of gamma-hydroxybutyrate (GHB), an endogenous metabolite of gamma-aminobutyric acid (GABA) a major inhibitory neurotransmitter. Evidence suggests a role for GHB as a neuromodulator/neurotransmitter. Under endogenous ...
Status:
US Approved Rx (2013)
First approved in 1999

Class (Stereo):
CHEMICAL (ABSOLUTE)



Doxercalciferol is a synthetic vitamin D2 analog that undergoes metabolic activation in vivo to form 1α,25-dihydroxyvitamin D2 (1α,25-(OH)2D2), a naturally occurring, biologically active form of vitamin D2. Doxercalciferol is indicated for the treatm...
Status:
US Approved Rx (2009)
First approved in 1995

Class (Stereo):
CHEMICAL (ACHIRAL)



Capsaicin is a topical analgesic that is FDA approved for the treatment of neuropathic pain associated with postherpetic neuralgia. Capsaicin is most often used as a topical analgesic and exists in many formulations of cream, liquid, and patch prepar...
Status:
US Approved Rx (2013)
First approved in 1992

Class (Stereo):
CHEMICAL (ABSOLUTE)



Finasteride is a synthetic 4-azasteroid compound. This drug is a competitive and specific inhibitor of Type II 5a-reductase, an intracellular enzyme that converts the androgen testosterone into 5α-dihydrotestosterone (DHT). Two distinct isozymes are ...
Status:
US Approved Rx (2004)
First approved in 1984

Class (Stereo):
CHEMICAL (ABSOLUTE)



Nicotine is a natural alkaloid obtained from the dried leaves and stems of the nightshade family of pants, such as Nicotiana tabacum and Nicotiana rustica, where it occurs in concentrations of 0.5-8%. Cigarette tobacco varies in its nicotine content,...
Status:
US Approved Rx (2012)
First approved in 1982

Class (Stereo):
CHEMICAL (RACEMIC)



Malathion is an organophosphate insecticide, an inhibitor of cholinesterase. In low doses (0.5%) malathion is used for treatment of pediculosis and scabies.
Status:
US Approved Rx (2002)
First approved in 1982

Class (Stereo):
CHEMICAL (RACEMIC)


Conditions:

Econazole (commonly used as the nitrate salt) is an antifungal medication of the imidazole class. It is a broad spectrum antimycotic with some action against Gram positive bacteria. It is used topically in dermatomycoses also orally and parenterally....
Status:
US Approved Rx (1978)
First approved in 1978

Class (Stereo):
CHEMICAL (ABSOLUTE)

Targets:


Natamycin (Pimaricin, Pimafucin, Natadrops, Natacyn) is a polyene antifungal agent originally isolated from Streptomyces natalensis found in a soil sample from Natal, South Africa. Natamycin was discovered in DSM laboratories in 1955. Similar to oth...
Status:
US Approved Rx (1975)
First approved in 1975

Class (Stereo):
CHEMICAL (ABSOLUTE)



Gluconic acid is a natural compound produced from glucose through a simple dehydrogenation reaction catalysed by glucose oxidase. Gluconic acid and its salts are used in the formulation of food, pharmaceutical and hygienic products.