U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS
This repository is under review for potential modification in compliance with Administration directives.

Showing 1 - 9 of 9 results

Status:
US Approved Rx (2012)
First approved in 1982

Class (Stereo):
CHEMICAL (RACEMIC)



Malathion is an organophosphate insecticide, an inhibitor of cholinesterase. In low doses (0.5%) malathion is used for treatment of pediculosis and scabies.
Status:
US Approved OTC
First approved in 2000

Class (Stereo):
CHEMICAL (ACHIRAL)

Conditions:

Piperonyl butoxide (PBO) is an organic compound used as a component of pesticide formulations. It is a waxy white solid. It is a semisynthetic derivative of safrole. It is used for the treatment of head, pubic (crab), and body lice. Piperonyl butoxid...
Status:
US Previously Marketed
First approved in 1946

Class (Stereo):
CHEMICAL (RACEMIC)

Conditions:

Isobornyl thiocyanoacetate (thanite) is an insecticide, used to control ants, houseflies and head lice. Thanite is known to be toxic to fish.
Status:
Possibly Marketed Outside US
First approved in 2011

Class (Stereo):
CHEMICAL (MIXED)



Cypermethrin is a synthetic, pyrethroid insecticide that has high insecticidal activity, low avian and mammalian toxicity. Cypermethrin works by quickly affecting the insect’s central nervous system. The major target site of cypermethrin is the sodiu...
Status:
Possibly Marketed Outside US

Class (Stereo):
CHEMICAL (EPIMERIC)


Conditions:

Bioallethrin is a synthetic pyrethroid with fast knock-down activity against household pest insects. It is used in public health against mosquitoes, houseflies and cockroaches. Bioallethrin is a mixture of two of the allethrin isomers, [1R,trans;1R] ...
mixture
Status:
US Approved Rx (2011)
First approved in 2011

Class:
MIXTURE

Conditions:

Spinosad is a natural mixture of pediculicidal tetracyclic macrolides—spinosyn A and spinosyn D in the ratio of 5:1. It is derived from species of actinomycetes bacteria - Saccharopolyspora spinosa and is a bacterial waste product produced by ferment...
mixture
Status:
US Approved Rx (2000)
First approved in 1986

Class:
MIXTURE



Permethrin is a synthetic pyrethrin derivative acts as a neurotoxin by depolarizing the nerve cell membrane. Permethrin disrupts the sodium channel current by which membrane repolarization is regulated resulting in fatal paralysis of the nerves in th...
Status:
US Approved Rx (2000)
First approved in 1986

Class (Stereo):
CHEMICAL (ABSOLUTE)



Permethrin is a synthetic pyrethrin derivative acts as a neurotoxin by depolarizing the nerve cell membrane. Permethrin disrupts the sodium channel current by which membrane repolarization is regulated resulting in fatal paralysis of the nerves in th...
Status:
US Approved Rx (2000)
First approved in 1986

Class (Stereo):
CHEMICAL (RACEMIC)



Permethrin is a synthetic pyrethrin derivative acts as a neurotoxin by depolarizing the nerve cell membrane. Permethrin disrupts the sodium channel current by which membrane repolarization is regulated resulting in fatal paralysis of the nerves in th...