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Details

Stereochemistry MIXED
Molecular Formula C22H19Cl2NO3
Molecular Weight 416.297
Optical Activity UNSPECIFIED
Defined Stereocenters 0 / 3
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CYPERMETHRIN

SMILES

CC1(C)C(C=C(Cl)Cl)C1C(=O)OC(C#N)C2=CC(OC3=CC=CC=C3)=CC=C2

InChI

InChIKey=KAATUXNTWXVJKI-UHFFFAOYSA-N
InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3

HIDE SMILES / InChI

Description

Cypermethrin is a synthetic, pyrethroid insecticide that has high insecticidal activity, low avian and mammalian toxicity. Cypermethrin works by quickly affecting the insect’s central nervous system. The major target site of cypermethrin is the sodium channel of the nerve membrane. A sodium channel exposed to cypermethrin can remain open much longer, even up to several seconds. It is used to control many pests including lepidopterous pests of cotton, fruit, and vegetable crops. In veterinary, it is applied topically for the control of ectoparasites such as ticks, fleas, lice and blowflies.

CNS Activity

Originator

Approval Year

Targets

Primary TargetPharmacologyConditionPotency

Conditions

ConditionModalityTargetsHighest PhaseProduct
Curative
ECTOMETHRIN
Curative
ECTOMETHRIN

PubMed

Sample Use Guides

In Vivo Use Guide
2.5 mg/kg spray at 62.5 ppm
Route of Administration: Topical
In Vitro Use Guide
Application of 200 uM cypermethrin in normal Ringer’s solution to a single nerve preparation immediately increases the threshold interval Vs - Vm until inexcitability of the nerve fiber occurs after about 4 min.