U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS
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Showing 1 - 10 of 104 results

Status:
US Approved Rx (2023)
First approved in 2008

Class (Stereo):
CHEMICAL (ACHIRAL)



Icosapent is an important polyunsaturated fatty acid found in fish oils. It serves as the precursor for the prostaglandin-3 and thromboxane-3 families. A diet rich in eicosapentaenoic acid lowers serum lipid concentration, reduces incidence of cardio...
Status:
US Approved Rx (1991)
First approved in 1978

Class (Stereo):
CHEMICAL (RACEMIC)



Sulindac is a nonsteroidal anti-inflammatory agent (NSAIA) of the arylalkanoic acid class that is marketed in the U.S. by Merck as Clinoril. Like other NSAIAs, it may be used in the treatment of acute or chronic inflammatory conditions. Sulindac is a...
Status:
US Approved Rx (1970)
First approved in 1970

Class (Stereo):
CHEMICAL (RACEMIC)



Mitotane is an oral chemotherapeutic agent indicated in the treatment of inoperable adrenal cortical carcinoma of both functional and nonfunctional types. Mitotane can best be described as an adrenal cytotoxic agent, although it can cause adrenal inh...
Status:
US Approved Rx (2018)
First approved in 1967

Class (Stereo):
CHEMICAL (ACHIRAL)



Ethacrynic acid is a monosulfonamyl loop or high ceiling diuretic. Ethacrynic acid acts on the ascending limb of the loop of Henle and on the proximal and distal tubules. Urinary output is usually dose dependent and related to the magnitude of fluid ...
Status:
US Approved Rx (1988)
First approved in 1963

Class (Stereo):
CHEMICAL (ABSOLUTE)



Vincristine is a vinca alkaloid antineoplastic agent used as a treatment for various cancers including breast cancer, Hodgkin's disease, Kaposi's sarcoma, and testicular cancer. The vinca alkaloids are structurally similar compounds comprised of 2 mu...
Status:
US Approved OTC
First approved in 1961

Class (Stereo):
CHEMICAL (ACHIRAL)



Pyrithione zinc is an antibacterial and antifungal agent developed by scientists in the 1930's. Since then it has been used to treat seborrheic dermatitis of the scalp and other skin conditions such as eczema, athlete's foot, and vitiligo, as well as...
Status:
US Approved OTC
First marketed in 1921

Class (Stereo):
CHEMICAL (ACHIRAL)



There is no available information related any biological and pharmaceutical application of ammonium tetrachlorozincate.
Status:
US Approved OTC
First marketed in 1921

Class (Stereo):
CHEMICAL (ACHIRAL)



Ferric Ammonium EDTA Solution is normally used as a photographic chemical for a bleaching agent in the process of colour washing. It is also used as a complexing, and oxidizing agent & as a fertilizer and catalyst. EDTA acid are colourless, water...
Status:
Investigational

Class (Stereo):
CHEMICAL (ABSOLUTE)


Conditions:

Taltobulin, also known as HTI-286 and SPA-110, is a fully synthetic analog of the natural tripeptide hemiasterlin, inhibits tubulin polymerization and circumvents transport-based resistance to taxanes. Taltobulin was a potent inhibitor of proliferati...
Bufotalin is a cardiotoxic bufanolide steroid, cardiac glycoside analogue, secreted by a number of toad species; a novel anti-osteoblastoma agent. Bufotalin is a traditional Chinese medicine prepared from the dried secretion of the auricular and skin...