U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Mon Oct 21 21:25:33 UTC 2019
Edited
by admin
on Mon Oct 21 21:25:33 UTC 2019
Protein Sub Type
Sequence Type COMPLETE
Record UNII
4AF605U6JN
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
MRP-2
Common Name English
ABC30
Common Name English
DJS
Common Name English
KIAA1010
Common Name English
MRP2
Common Name English
CMOAT1
Common Name English
CANALICULAR MULTIDRUG RESISTANCE PROTEIN
Common Name English
CMOAT
Common Name English
CANALICULAR MULTISPECIFIC ORGANIC ANION TRANSPORTER 1
Common Name English
MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 2
Common Name English
CMRP
Common Name English
ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 2
Common Name English
ABCC2
Common Name English
Classification Tree Code System Code
UCSF-FDA TRANSPORTAL ABCC2
Created by admin on Mon Oct 21 21:25:33 UTC 2019 , Edited by admin on Mon Oct 21 21:25:33 UTC 2019
Code System Code Type Description
UNIPROT
Q92887
Created by admin on Mon Oct 21 21:25:33 UTC 2019 , Edited by admin on Mon Oct 21 21:25:33 UTC 2019
PRIMARY
Glycosylation Type HUMAN
Glycosylation Link Type Site
N 1_7
N 1_12
N 1_1011
Related Record Type Details
INHIBITOR -> TARGET
INHIBITOR -> TRANSPORTER
NON-INHIBITOR -> TRANSPORTER
INHIBITOR -> TRANSPORTER
SUBSTRATE -> TRANSPORTER
INHIBITOR -> TRANSPORTER
INHIBITOR -> TRANSPORTER
INHIBITOR -> TRANSPORTER
IC50
INHIBITOR -> METABOLIC ENZYME
NON-SUBSTRATE -> TRANSPORTER
INHIBITOR -> TRANSPORTER
SUBSTRATE -> METABOLIC ENZYME
INHIBITOR -> TRANSPORTER
SUBSTRATE -> TRANSPORTER
INHIBITOR -> TRANSPORTER
INHIBITOR -> TRANSPORTER
INHIBITOR -> TRANSPORTER
SUBSTRATE -> TRANSPORTER
Based on in-vitro studies, eluxadoline appears to be a substrate for OAT3, OATP1B1, BSEP, and MRP2
INHIBITOR -> TRANSPORTER
INHIBITOR -> TRANSPORTER
INHIBITOR -> TRANSPORTER
NON-INHIBITOR -> TRANSPORTER
INHIBITOR -> TRANSPORTER
SUBSTRATE -> TRANSPORTER
INHIBITOR -> TRANSPORTER
SUBSTRATE -> TRANSPORTER
SUBSTRATE -> TRANSPORTER
SUBSTRATE -> TRANSPORTER
INHIBITOR -> METABOLIC ENZYME
SUBSTRATE -> TRANSPORTER
INHIBITOR -> TRANSPORTER
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL