TECHNETIUM TC-99M MEBROFENIN

Details

Stereochemistry	ACHIRAL
Molecular Formula	2C15H17BrN2O5.Tc
Molecular Weight	869.326
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of TECHNETIUM TC-99M MEBROFENIN

Structure Search

SMILES

[99Tc+4].CC1=CC(C)=C(NC(=O)CN(CC([O-])=O)CC([O-])=O)C(C)=C1Br.CC2=CC(C)=C(NC(=O)CN(CC([O-])=O)CC([O-])=O)C(C)=C2Br

InChI

InChIKey=MGKWQLBBVFGWLJ-FCHARDOESA-J

InChI=1S/2C15H19BrN2O5.Tc/c2*1-8-4-9(2)15(10(3)14(8)16)17-11(19)5-18(6-12(20)21)7-13(22)23;/h2*4H,5-7H2,1-3H3,(H,17,19)(H,20,21)(H,22,23);/q;;+4/p-4/i;;1+1

HIDE SMILES / InChI

Molecular Formula	C15H17BrN2O5
Molecular Weight	385.21
Charge	-2
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	Tc
Molecular Weight	98.906254554
Charge	4
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.hindawi.com/journals/stni/2014/839369/
Curator's Comment: description was created based on several sources, including https://www.ncbi.nlm.nih.gov/books/NBK215133/ | https://www.iaea.org/OurWork/ST/NE/NEFW/Technical-Areas/RRS/documents /mo99/WORKINGMATERIALSmo99CM.pdf | https://www.ncbi.nlm.nih.gov/pubmed/27854401

Molybdenum-99 (99Mo, half-life = 66 h) is a parent radionuclide of a diagnostic nuclear isotope. It decays in technetium-99 m (half-life = 6 h), which is used in over 30 million procedures per year around the world. Between 95 and 98 percent of Mo-99 is currently being produced using highly enriched uranium (HEU) targets. Other medical isotopes such as iodine-131 (I-131) and xenon-133 (Xe-133) are by-products of the Mo-99 production process and will be sufficiently available if Mo-99 is available.

Approval Year

Conditions

Condition	Modality	Highest Phase	Product
Unknown 2596
bone problems 40 Sources: https://www.drugs.com/cons/osteolite.html	Diagnostic	Approved 8583	OSTEOLITE Approved Use Unknown Launch Date 1977
osteogenesis 40 Sources: https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/018035s032lbl.pdf	Diagnostic	Approved 8583	DRAXIMAGE MDP-10 Approved Use MDP-25 (Kit for the Preparation of Technetium Tc 99m Medronate) may be used as a bone imaging agent to delineate areas of altered osteogenesis. Launch Date 1978

PubMed

Title	Date	PubMed
Future of low specific activity molybdenum-99/technetium-99m generator.	2012-10	22642420

Patents

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:07:19 GMT 2025` Edited by `admin` on `Mon Mar 31 18:07:19 GMT 2025`
Record UNII	F2NQ468L52
Record Status	`Validated (UNII)`
Record Version

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Related Record	Type

Name

Type

Language

TECHNETIUM TC 99M MEBROFENIN

Preferred Name

English

TECHNETIUM TC-99M MEBROFENIN

Common Name

English

Technetium (99mTc) mebrofenin

Common Name

English

CHOLETEC

Brand Name

English

TECHNETIUM TC 99M MEBROFENIN [USAN]

Common Name

English

TECHNETIUM (99m TC) MEBROFENIN

Common Name

English

TECHNETIUM TC 99M MEBROFENIN [USP IMPURITY]

Common Name

English

99MTC-MEBROFENIN

Common Name

English

Technetium tc 99m mebrofenin [WHO-DD]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C2124