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Approval Year

Substance Class Protein
Created
by admin
on Fri Jun 25 22:20:08 UTC 2021
Edited
by admin
on Fri Jun 25 22:20:08 UTC 2021
Protein Sub Type
Sequence Type COMPLETE
Record UNII
2PDN1S3FVX
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR ALPHA
Common Name English
PPAR-ALPHA
Common Name English
NUCLEAR RECEPTOR SUBFAMILY 1 GROUP C MEMBER 1
Common Name English
PPAR-.ALPHA.
Common Name English
PPARA
Common Name English
Code System Code Type Description
FDA UNII
2PDN1S3FVX
Created by admin on Fri Jun 25 22:20:08 UTC 2021 , Edited by admin on Fri Jun 25 22:20:08 UTC 2021
PRIMARY
UNIPROT
Q07869
Created by admin on Fri Jun 25 22:20:08 UTC 2021 , Edited by admin on Fri Jun 25 22:20:08 UTC 2021
PRIMARY
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INHIBITOR -> TARGET
WEAK AGONIST->TARGET
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SELECTIVE
AGONIST -> TARGET
AGONIST -> TARGET
AGONIST -> TARGET
AGONIST -> TARGET
Tesaglitazar is a novel dual-acting peroxisome proliferator-activated receptor alpha and gamma agonist.
AGONIST -> TARGET
Ki=7.1 micromolar (Supplementary Fig. S5; http://clincancerres.aacrjournals.org/content/22/10/2508.figures-only)
IN-VITRO
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The PPAR? potency and selectivity of 3 were further confirmed by testing it in cotransfection assays in HepG2 cells using full length human PPAR? and PPAR? receptors..
EC50
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT CHEMICAL
Molecular Formula CHEMICAL