Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C18H25Cl3O2 |
| Molecular Weight | 379.749 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
OC(=O)C(Cl)(Cl)CCCCCCCCCCC1=CC=C(Cl)C=C1
InChI
InChIKey=GPCJDSXBRMKASP-UHFFFAOYSA-N
InChI=1S/C18H25Cl3O2/c19-16-12-10-15(11-13-16)9-7-5-3-1-2-4-6-8-14-18(20,21)17(22)23/h10-13H,1-9,14H2,(H,22,23)
| Molecular Formula | C18H25Cl3O2 |
| Molecular Weight | 379.749 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Effect of PPARalpha activation of macrophages on the secretion of inflammatory cytokines in cultured adipocytes. | 2007-04-30 |
|
| Drug evaluation: K-111, an insulin-sensitizing peroxisome proliferator-activated receptor alpha agonist. | 2007-04 |
|
| Reduced coronary reserve in response to short-term ischaemia and vasoactive drugs in ex vivo hearts from diabetic mice. | 2006-03 |
|
| Skeletal muscle glycogen synthase subcellular localization: effects of insulin and PPAR-alpha agonist (K-111) administration in rhesus monkeys. | 2005-06 |
|
| Effect of BM 17.0744, a PPARalpha ligand, on the metabolism of perfused hearts from control and diabetic mice. | 2005-02 |
|
| Human adipocyte fatty acid-binding protein (aP2) gene promoter-driven reporter assay discriminates nonlipogenic peroxisome proliferator-activated receptor gamma ligands. | 2004-11 |
|
| Biochemical and morphological effects of K-111, a peroxisome proliferator-activated receptor (PPAR)alpha activator, in non-human primates. | 2004-07-15 |
|
| The effects of K-111, a new insulin-sensitizer, on metabolic syndrome in obese prediabetic rhesus monkeys. | 2003-10 |
|
| Cardiac function and metabolism in Type 2 diabetic mice after treatment with BM 17.0744, a novel PPAR-alpha activator. | 2002-09 |
|
| Peroxisome proliferator-activated receptor-alpha ligands inhibit cardiac lipoprotein lipase activity. | 2001-08 |
|
| BM 17.0744: a structurally new antidiabetic compound with insulin-sensitizing and lipid-lowering activity. | 1999-01 |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Wed Apr 02 09:59:12 GMT 2025
by
admin
on
Wed Apr 02 09:59:12 GMT 2025
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| Record UNII |
TM9XQR923G
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| Record Status |
Validated (UNII)
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221564-97-2
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TM9XQR923G
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DTXSID901286589
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9929731
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| Related Record | Type | Details | ||
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TARGET -> ACTIVATOR |
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| Related Record | Type | Details | ||
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ACTIVE MOIETY |
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