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Restrict the search for
sulfanilamide
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There is one exact (name or code) match for sulfanilamide
Status:
US Previously Marketed
Source:
AVC by MYLAN SPECIALITY LP
(1965)
Source URL:
First marketed in 1936
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
Sulfanilamide is an anibiotic drug, which has been used for decades for the treatment of vulvovaginal candidiasis. The drug blocks folic acid synthesis in bacterias by inhibitin the enzyme dihydropteroate synthase.
Status:
US Previously Marketed
Source:
AVC by MYLAN SPECIALITY LP
(1965)
Source URL:
First marketed in 1936
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
Sulfanilamide is an anibiotic drug, which has been used for decades for the treatment of vulvovaginal candidiasis. The drug blocks folic acid synthesis in bacterias by inhibitin the enzyme dihydropteroate synthase.
Status:
US Approved Rx
(1982)
Source:
NDA018578
(1982)
Source URL:
First approved in 1973
Source:
NDA017381
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Status:
US Approved Rx
(2019)
Source:
ANDA212231
(2019)
Source URL:
First approved in 1961
Source:
GANTANOL by ROCHE
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
Sulfamethoxazole is a synthetic antibacterial drug,which is used in combination with trimethoprim (Bactrim, Septra) for the treatment or prevention of infections that are proven or strongly suspected to be caused by bacteria. Sulfamethoxazole acts by inhibiting folic acid synthesis via enzyme called dihydropteroate synthase.
Status:
US Approved Rx
(1994)
Source:
ANDA040091
(1994)
Source URL:
First approved in 1941
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Sulfadiazine is a sulfonamide antibiotic. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle. Bacterial sensitivity is the same for the various sulfonamides, and resistance to one sulfonamide indicates resistance to all. Most sulfonamides are readily absorbed orally. However, parenteral administration is difficult, since the soluble sulfonamide salts are highly alkaline and irritating to the tissues. The sulfonamides are widely distributed throughout all tissues. High levels are achieved in pleural, peritoneal, synovial, and ocular fluids. Although these drugs are no longer used to treat meningitis, CSF levels are high in meningeal infections. Their antibacterial action is inhibited by pus. Sulfadiazine is a competitive inhibitor of the bacterial enzyme dihydropteroate synthetase. This enzyme is needed for the proper processing of para-aminobenzoic acid (PABA) which is essential for folic acid synthesis. The inhibited reaction is necessary in these organisms for the synthesis of folic acid. Used for the treatment of rheumatic fever and meningococcal meningitis.
Class (Stereo):
CHEMICAL (ACHIRAL)
Sulfasymazine is a sulfanilamide derivative patented by American Cyanamid Co. as antibacterial agents for Staphylococcus and Streptococcus infections. In preclinical models, Sulfasymazine shows activity on a dosage basis ranged from 2- to 10-fold that of sulfisoxazole, and from 1/3 to equal on a blood-level basis, but was not as potent as sulfadiazine.
Class (Stereo):
CHEMICAL (ACHIRAL)
Glyprothiazol (VK 57 or RP 2254) is a sulfonamide derivative. This compound lowers blood glucose levels by increasing the release of insulin from the pancreas. It stimulates insulin secretion through a direct action on pancreatic islets. Glyprothiazol was the first of oral hypoglycemic sulfonamides used in the treatment of type 2 diabetes mellitus.
Class (Stereo):
CHEMICAL (ACHIRAL)
Sulfatroxazole is a sulfamide derivative patented by Swiss multinational healthcare company F. Hoffmann-La Roche & Co., A.-G. as an antibacterial agent and bacteriostatic antibiotic. Sulfatroxazole competitively inhibits dihydropteroate synthase preventing the formation of dihydropteroic acid, a precursor of folic acid which is required for bacterial growth. Sulfatroxazole is a component present in various veterinary drugs.
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
Glybuthiazole is a sulfonamide derivative with antihyperglycemic activity, which possesses anti-diabetic properties. It is able to lower blood glucose levels by increasing the release of insulin from pancreatic beta cells.
Status:
Investigational
Source:
INN:delfantrine [INN]
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Delfantrine is an analgesic, antiinflammatory agent, developed by Ciba.
