GLYBUTHIAZOL

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C12H16N4O2S2
Molecular Weight	312.411
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of GLYBUTHIAZOL

Structure Search

SMILES

CC(C)(C)C1=NN=C(NS(=O)(=O)C2=CC=C(N)C=C2)S1

InChI

InChIKey=DVQVBLBKEXITIK-UHFFFAOYSA-N

InChI=1S/C12H16N4O2S2/c1-12(2,3)10-14-15-11(19-10)16-20(17,18)9-6-4-8(13)5-7-9/h4-7H,13H2,1-3H3,(H,15,16)

HIDE SMILES / InChI

Description
Sources: https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf

Glybuthiazole is a sulfonamide derivative with antihyperglycemic activity, which possesses anti-diabetic properties. It is able to lower blood glucose levels by increasing the release of insulin from pancreatic beta cells.

Approval Year

Conditions

Conditions

Condition	Modality	Targets	Highest Phase	Product
Diabetes mellitus 93 Sources: http://www.google.com/patents/US8623819	Primary		Not Provided 511	Unknown Approved Use Unknown

Patents

Patents

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

Unknown

Name

Type

Language

GLYBUTHIAZOL

Official Name

English

GLYBUTHIAZOLE

Preferred Name

English

NSC-23010

Code

English

RP-2259

Code

English

glybuthiazol [INN]

Common Name

English

GLYBUTHIAZOLE [MI]

Common Name

English

N(SUP 1)-(5-TERT-BUTYL-1,3,4-THIADIAZOL-2-YL)SULFANILAMIDE

Systematic Name

English

RP 2259

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C29711

Created by admin on Mon Mar 31 18:28:38 GMT 2025 , Edited by admin on Mon Mar 31 18:28:38 GMT 2025

Code System Code Type Description

CAS

535-65-9

Created by admin on Mon Mar 31 18:28:38 GMT 2025 , Edited by admin on Mon Mar 31 18:28:38 GMT 2025

PRIMARY

EPA CompTox

DTXSID4057762

Created by admin on Mon Mar 31 18:28:38 GMT 2025 , Edited by admin on Mon Mar 31 18:28:38 GMT 2025

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FDA UNII

35421N8E8W

Created by admin on Mon Mar 31 18:28:38 GMT 2025 , Edited by admin on Mon Mar 31 18:28:38 GMT 2025

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DRUG CENTRAL

3268

Created by admin on Mon Mar 31 18:28:38 GMT 2025 , Edited by admin on Mon Mar 31 18:28:38 GMT 2025

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EVMPD

SUB07946MIG

Created by admin on Mon Mar 31 18:28:38 GMT 2025 , Edited by admin on Mon Mar 31 18:28:38 GMT 2025

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NSC

23010

Created by admin on Mon Mar 31 18:28:38 GMT 2025 , Edited by admin on Mon Mar 31 18:28:38 GMT 2025

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NCI_THESAURUS

C72803

Created by admin on Mon Mar 31 18:28:38 GMT 2025 , Edited by admin on Mon Mar 31 18:28:38 GMT 2025

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ECHA (EC/EINECS)

208-615-8

Created by admin on Mon Mar 31 18:28:38 GMT 2025 , Edited by admin on Mon Mar 31 18:28:38 GMT 2025

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INN

708

Created by admin on Mon Mar 31 18:28:38 GMT 2025 , Edited by admin on Mon Mar 31 18:28:38 GMT 2025

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MERCK INDEX

m5785

Created by admin on Mon Mar 31 18:28:38 GMT 2025 , Edited by admin on Mon Mar 31 18:28:38 GMT 2025

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Merck Index

SMS_ID

100000084230

Created by admin on Mon Mar 31 18:28:38 GMT 2025 , Edited by admin on Mon Mar 31 18:28:38 GMT 2025

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ChEMBL

CHEMBL94087

Created by admin on Mon Mar 31 18:28:38 GMT 2025 , Edited by admin on Mon Mar 31 18:28:38 GMT 2025

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PUBCHEM

10811

Created by admin on Mon Mar 31 18:28:38 GMT 2025 , Edited by admin on Mon Mar 31 18:28:38 GMT 2025

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ACTIVE MOIETY


					35421N8E8W