GLYPROTHIAZOL

Details

Stereochemistry	ACHIRAL
Molecular Formula	C11H14N4O2S2
Molecular Weight	298.384
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC(C)C1=NN=C(NS(=O)(=O)C2=CC=C(N)C=C2)S1

InChI

InChIKey=OPIGMRDAPFQALU-UHFFFAOYSA-N

InChI=1S/C11H14N4O2S2/c1-7(2)10-13-14-11(18-10)15-19(16,17)9-5-3-8(12)4-6-9/h3-7H,12H2,1-2H3,(H,14,15)

HIDE SMILES / InChI

Molecular Formula	C11H14N4O2S2
Molecular Weight	298.384
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://pubchem.ncbi.nlm.nih.gov/compound/Glypinamide | https://www.ncbi.nlm.nih.gov/pubmed/17978743

Glyprothiazol (VK 57 or RP 2254) is a sulfonamide derivative. This compound lowers blood glucose levels by increasing the release of insulin from the pancreas. It stimulates insulin secretion through a direct action on pancreatic islets. Glyprothiazol was the first of oral hypoglycemic sulfonamides used in the treatment of type 2 diabetes mellitus.

Approval Year

Substance Class	Chemical Created by `admin` on `Sat Dec 16 16:43:39 GMT 2023` Edited by `admin` on `Sat Dec 16 16:43:39 GMT 2023`
Record UNII	1804FJN4MO
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

GLYPROTHIAZOL

Official Name

English

VK-57

Code

English

N(SUP 1)-(5-ISOPROPYL-1,3,4-THIADIAZOL-2-YL)SULFANILAMIDE

Systematic Name

English

RP 2254

Code

English

glyprothiazol [INN]

Common Name

English

RP-2254

Code

English

GLYPROTHIZOL

Common Name

English

PASIT

Common Name

English

IPTD

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C29711