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Details

Stereochemistry ACHIRAL
Molecular Formula C11H14N4O2S2
Molecular Weight 298.384
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of GLYPROTHIAZOL

SMILES

CC(C)C1=NN=C(NS(=O)(=O)C2=CC=C(N)C=C2)S1

InChI

InChIKey=OPIGMRDAPFQALU-UHFFFAOYSA-N
InChI=1S/C11H14N4O2S2/c1-7(2)10-13-14-11(18-10)15-19(16,17)9-5-3-8(12)4-6-9/h3-7H,12H2,1-2H3,(H,14,15)

HIDE SMILES / InChI
Glyprothiazol (VK 57 or RP 2254) is a sulfonamide derivative. This compound lowers blood glucose levels by increasing the release of insulin from the pancreas. It stimulates insulin secretion through a direct action on pancreatic islets. Glyprothiazol was the first of oral hypoglycemic sulfonamides used in the treatment of type 2 diabetes mellitus.

Approval Year

Name Type Language
GLYPROTHIAZOL
INN  
INN  
Official Name English
VK-57
Code English
N(SUP 1)-(5-ISOPROPYL-1,3,4-THIADIAZOL-2-YL)SULFANILAMIDE
Systematic Name English
RP 2254
Code English
glyprothiazol [INN]
Common Name English
RP-2254
Code English
GLYPROTHIZOL
Common Name English
PASIT
Common Name English
IPTD
Code English
Classification Tree Code System Code
NCI_THESAURUS C29711
Created by admin on Sat Dec 16 16:43:39 GMT 2023 , Edited by admin on Sat Dec 16 16:43:39 GMT 2023
Code System Code Type Description
EVMPD
SUB07957MIG
Created by admin on Sat Dec 16 16:43:39 GMT 2023 , Edited by admin on Sat Dec 16 16:43:39 GMT 2023
PRIMARY
SMS_ID
100000084255
Created by admin on Sat Dec 16 16:43:39 GMT 2023 , Edited by admin on Sat Dec 16 16:43:39 GMT 2023
PRIMARY
NCI_THESAURUS
C65812
Created by admin on Sat Dec 16 16:43:39 GMT 2023 , Edited by admin on Sat Dec 16 16:43:39 GMT 2023
PRIMARY
FDA UNII
1804FJN4MO
Created by admin on Sat Dec 16 16:43:39 GMT 2023 , Edited by admin on Sat Dec 16 16:43:39 GMT 2023
PRIMARY
EPA CompTox
DTXSID80229994
Created by admin on Sat Dec 16 16:43:39 GMT 2023 , Edited by admin on Sat Dec 16 16:43:39 GMT 2023
PRIMARY
INN
707
Created by admin on Sat Dec 16 16:43:39 GMT 2023 , Edited by admin on Sat Dec 16 16:43:39 GMT 2023
PRIMARY
ChEMBL
CHEMBL450117
Created by admin on Sat Dec 16 16:43:39 GMT 2023 , Edited by admin on Sat Dec 16 16:43:39 GMT 2023
PRIMARY
PUBCHEM
66458
Created by admin on Sat Dec 16 16:43:39 GMT 2023 , Edited by admin on Sat Dec 16 16:43:39 GMT 2023
PRIMARY
CAS
80-34-2
Created by admin on Sat Dec 16 16:43:39 GMT 2023 , Edited by admin on Sat Dec 16 16:43:39 GMT 2023
PRIMARY