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Details

Stereochemistry ACHIRAL
Molecular Formula C10H11N3O3S
Molecular Weight 253.278
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of SULFAMETHOXAZOLE

SMILES

CC1=CC(NS(=O)(=O)C2=CC=C(N)C=C2)=NO1

InChI

InChIKey=JLKIGFTWXXRPMT-UHFFFAOYSA-N
InChI=1S/C10H11N3O3S/c1-7-6-10(12-16-7)13-17(14,15)9-4-2-8(11)3-5-9/h2-6H,11H2,1H3,(H,12,13)

HIDE SMILES / InChI

Molecular Formula C10H11N3O3S
Molecular Weight 253.278
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Sulfamethoxazole is a synthetic antibacterial drug,which is used in combination with trimethoprim (Bactrim, Septra) for the treatment or prevention of infections that are proven or strongly suspected to be caused by bacteria. Sulfamethoxazole acts by inhibiting folic acid synthesis via enzyme called dihydropteroate synthase.

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
0.71 µM [IC50]
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Curative
BACTRIM

Approved Use

To reduce the development of drug-resistant bacteria and maintain the effectiveness of Bactrim (sulfamethoxazole and trimethoprim) tablets and other antibacterial drugs, Bactrim (sulfamethoxazole and trimethoprim) tablets should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to empiric selection of therapy.

Launch Date

1973
Curative
BACTRIM

Approved Use

To reduce the development of drug-resistant bacteria and maintain the effectiveness of Bactrim (sulfamethoxazole and trimethoprim) tablets and other antibacterial drugs, Bactrim (sulfamethoxazole and trimethoprim) tablets should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to empiric selection of therapy.

Launch Date

1973
Curative
BACTRIM

Approved Use

To reduce the development of drug-resistant bacteria and maintain the effectiveness of Bactrim (sulfamethoxazole and trimethoprim) tablets and other antibacterial drugs, Bactrim (sulfamethoxazole and trimethoprim) tablets should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to empiric selection of therapy.

Launch Date

1973
Curative
BACTRIM

Approved Use

To reduce the development of drug-resistant bacteria and maintain the effectiveness of Bactrim (sulfamethoxazole and trimethoprim) tablets and other antibacterial drugs, Bactrim (sulfamethoxazole and trimethoprim) tablets should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to empiric selection of therapy.

Launch Date

1973
Curative
BACTRIM

Approved Use

To reduce the development of drug-resistant bacteria and maintain the effectiveness of Bactrim (sulfamethoxazole and trimethoprim) tablets and other antibacterial drugs, Bactrim (sulfamethoxazole and trimethoprim) tablets should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to empiric selection of therapy.

Launch Date

1973
Curative
BACTRIM

Approved Use

To reduce the development of drug-resistant bacteria and maintain the effectiveness of Bactrim (sulfamethoxazole and trimethoprim) tablets and other antibacterial drugs, Bactrim (sulfamethoxazole and trimethoprim) tablets should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to empiric selection of therapy.

Launch Date

1973
Cmax

Cmax

ValueDoseCo-administeredAnalytePopulation
94.42 μg/mL
1200 mg single, oral
dose: 1200 mg
route of administration: Oral
experiment type: SINGLE
co-administered:
SULFAMETHOXAZOLE plasma
Homo sapiens
population: HEALTHY
age: ADULT
sex: MALE
food status: FASTED
46.3 μg/mL
800 mg single, oral
dose: 800 mg
route of administration: Oral
experiment type: SINGLE
co-administered: TRIMETHOPRIM
SULFAMETHOXAZOLE plasma
Homo sapiens
population: UNKNOWN
age: UNKNOWN
sex: UNKNOWN
food status: UNKNOWN
AUC

AUC

ValueDoseCo-administeredAnalytePopulation
1202.5 μg × h/mL
1200 mg single, oral
dose: 1200 mg
route of administration: Oral
experiment type: SINGLE
co-administered:
SULFAMETHOXAZOLE plasma
Homo sapiens
population: HEALTHY
age: ADULT
sex: MALE
food status: FASTED
T1/2

T1/2

ValueDoseCo-administeredAnalytePopulation
12.8 h
800 mg single, oral
dose: 800 mg
route of administration: Oral
experiment type: SINGLE
co-administered: TRIMETHOPRIM
SULFAMETHOXAZOLE plasma
Homo sapiens
population: UNKNOWN
age: UNKNOWN
sex: UNKNOWN
food status: UNKNOWN
Funbound

Funbound

ValueDoseCo-administeredAnalytePopulation
30%
800 mg single, oral
dose: 800 mg
route of administration: Oral
experiment type: SINGLE
co-administered: TRIMETHOPRIM
SULFAMETHOXAZOLE plasma
Homo sapiens
population: UNKNOWN
age: UNKNOWN
sex: UNKNOWN
food status: UNKNOWN
Doses

Doses

DosePopulationAdverse events​
800 mg 2 times / day multiple, oral
Recommended
Dose: 800 mg, 2 times / day
Route: oral
Route: multiple
Dose: 800 mg, 2 times / day
Sources:
unhealthy, 86 years
Health Status: unhealthy
Age Group: 86 years
Sex: F
Sources:
Disc. AE: Insomnia...
Other AEs: Fear, Behaviour abnormal...
AEs leading to
discontinuation/dose reduction:
Insomnia
Other AEs:
Fear
Behaviour abnormal
Visual hallucinations
Disorientation
Auditory hallucinations
Sources:
1600 mg multiple, oral
Recommended
Dose: 1600 mg
Route: oral
Route: multiple
Dose: 1600 mg
Sources:
unhealthy, adult
Health Status: unhealthy
Age Group: adult
Sources:
Other AEs: Leucopenia...
Other AEs:
Leucopenia
Sources:
2400 mg 1 times / day single, oral
Highest studied dose
Dose: 2400 mg, 1 times / day
Route: oral
Route: single
Dose: 2400 mg, 1 times / day
Sources:
unhealthy, mean age 20 years
1200 mg 2 times / day multiple, oral
Recommended
Dose: 1200 mg, 2 times / day
Route: oral
Route: multiple
Dose: 1200 mg, 2 times / day
Sources:
unhealthy, mean age 47 years
Health Status: unhealthy
Age Group: mean age 47 years
Sources:
Disc. AE: Allergic reaction...
Other AEs: Granulocytopenia...
AEs leading to
discontinuation/dose reduction:
Allergic reaction (3.8%)
Other AEs:
Granulocytopenia
Sources:
800 mg 2 times / day multiple, oral
Recommended
Dose: 800 mg, 2 times / day
Route: oral
Route: multiple
Dose: 800 mg, 2 times / day
Sources:
unhealthy, mean age 58 years
Health Status: unhealthy
Age Group: mean age 58 years
Sex: M+F
Sources:
Disc. AE: Skin rash...
AEs leading to
discontinuation/dose reduction:
Skin rash (4.9%)
Sources:
1200 mg multiple, oral
Studied dose
Dose: 1200 mg
Route: oral
Route: multiple
Dose: 1200 mg
Sources:
unhealthy, median age 69 years
Health Status: unhealthy
Age Group: median age 69 years
Sex: M+F
Sources:
Other AEs: Agranulocytosis...
Other AEs:
Agranulocytosis (9.9%)
Sources:
AEs

AEs

AESignificanceDosePopulation
Auditory hallucinations
800 mg 2 times / day multiple, oral
Recommended
Dose: 800 mg, 2 times / day
Route: oral
Route: multiple
Dose: 800 mg, 2 times / day
Sources:
unhealthy, 86 years
Health Status: unhealthy
Age Group: 86 years
Sex: F
Sources:
Behaviour abnormal
800 mg 2 times / day multiple, oral
Recommended
Dose: 800 mg, 2 times / day
Route: oral
Route: multiple
Dose: 800 mg, 2 times / day
Sources:
unhealthy, 86 years
Health Status: unhealthy
Age Group: 86 years
Sex: F
Sources:
Disorientation
800 mg 2 times / day multiple, oral
Recommended
Dose: 800 mg, 2 times / day
Route: oral
Route: multiple
Dose: 800 mg, 2 times / day
Sources:
unhealthy, 86 years
Health Status: unhealthy
Age Group: 86 years
Sex: F
Sources:
Fear
800 mg 2 times / day multiple, oral
Recommended
Dose: 800 mg, 2 times / day
Route: oral
Route: multiple
Dose: 800 mg, 2 times / day
Sources:
unhealthy, 86 years
Health Status: unhealthy
Age Group: 86 years
Sex: F
Sources:
Visual hallucinations
800 mg 2 times / day multiple, oral
Recommended
Dose: 800 mg, 2 times / day
Route: oral
Route: multiple
Dose: 800 mg, 2 times / day
Sources:
unhealthy, 86 years
Health Status: unhealthy
Age Group: 86 years
Sex: F
Sources:
Insomnia Disc. AE
800 mg 2 times / day multiple, oral
Recommended
Dose: 800 mg, 2 times / day
Route: oral
Route: multiple
Dose: 800 mg, 2 times / day
Sources:
unhealthy, 86 years
Health Status: unhealthy
Age Group: 86 years
Sex: F
Sources:
Leucopenia
1600 mg multiple, oral
Recommended
Dose: 1600 mg
Route: oral
Route: multiple
Dose: 1600 mg
Sources:
unhealthy, adult
Health Status: unhealthy
Age Group: adult
Sources:
Granulocytopenia
1200 mg 2 times / day multiple, oral
Recommended
Dose: 1200 mg, 2 times / day
Route: oral
Route: multiple
Dose: 1200 mg, 2 times / day
Sources:
unhealthy, mean age 47 years
Health Status: unhealthy
Age Group: mean age 47 years
Sources:
Allergic reaction 3.8%
Disc. AE
1200 mg 2 times / day multiple, oral
Recommended
Dose: 1200 mg, 2 times / day
Route: oral
Route: multiple
Dose: 1200 mg, 2 times / day
Sources:
unhealthy, mean age 47 years
Health Status: unhealthy
Age Group: mean age 47 years
Sources:
Skin rash 4.9%
Disc. AE
800 mg 2 times / day multiple, oral
Recommended
Dose: 800 mg, 2 times / day
Route: oral
Route: multiple
Dose: 800 mg, 2 times / day
Sources:
unhealthy, mean age 58 years
Health Status: unhealthy
Age Group: mean age 58 years
Sex: M+F
Sources:
Agranulocytosis 9.9%
1200 mg multiple, oral
Studied dose
Dose: 1200 mg
Route: oral
Route: multiple
Dose: 1200 mg
Sources:
unhealthy, median age 69 years
Health Status: unhealthy
Age Group: median age 69 years
Sex: M+F
Sources:
Overview

OverviewOther

Other InhibitorOther SubstrateOther Inducer





Drug as perpetrator​Drug as victim

Drug as victim

TargetModalityActivityMetaboliteClinical evidence
yes
yes
yes (co-administration study)
Comment: ketoconazole did not inhibit hydroxylamine formation or any route of SMX metabolism; fluconazole decreased 5OH-SMX-acetate by64.0%
Page: 3.0
PubMed

PubMed

TitleDatePubMed
Recognition of sulfamethoxazole and its reactive metabolites by drug-specific CD4+ T cells from allergic individuals.
2000 Jun 15
A common polymorphism associated with antibiotic-induced cardiac arrhythmia.
2000 Sep 12
Tg.AC genetically altered mouse: assay working group overview of available data.
2001
Molecular characterization of Salmonella weltevreden isolated from poultry: evidence of conjugal transfer of plasmid and antibiotic resistance.
2001
Infrared studies on Co and Cd complexes of sulfamethoxazole.
2001 Apr
Practice guidelines for the treatment of uncomplicated cystitis.
2001 Aug
Vibrio cholerae O1 outbreak isolates in Mozambique and South Africa in 1998 are multiple-drug resistant, contain the SXT element and the aadA2 gene located on class 1 integrons.
2001 Dec
Molecular epidemiological analysis of Salmonella enterica serotype Derby infections in Hong Kong.
2001 Feb
Viable but nonculturable uropathogenic bacteria are present in the mouse urinary tract following urinary tract infection and antibiotic therapy.
2001 Feb
Resistance patterns of non-O157 Shiga toxin-producing Escherichia coli (STEC) strains isolated from animals, food and asymptomatic human carriers in Switzerland.
2001 Feb
In vitro quantitative analysis of (3)H-uracil incorporation by Sarcocytis neurona to determine efficacy of anti-protozoal agents.
2001 Feb 26
Multifocal Staphylococcus aureus infection originating from the sacroiliac joint in a patient with rheumatoid arthritis.
2001 Jan
Drug interactions as a cause of overanticoagulation on phenprocoumon or acenocoumarol predominantly concern antibacterial drugs.
2001 Jun
Impact of prophylaxis for Mycobacterium avium complex on bacterial infections in patients with advanced human immunodeficiency virus disease.
2001 Jun 1
Indirect potentiometric titration of sulphamethoxazole in the presence of trimethoprim in co-trimazole tablets using copper based mercury film electrode.
2001 Mar
Serogroups and antimicrobial susceptibility among Escherichia coli isolated from farmed mink (Mustela vison Schreiber) in Denmark.
2001 Mar 20
Induction of delayed-type hypersensitivity to sulfamethoxazole in mice: role of metabolites.
2001 Mar 8
Association between antibiotic resistance and the expression of Dr adhesin among uropathogenic Escherichia coli.
2001 Mar-Apr
Twenty-six-week carcinogenicity study of sulfamethoxazole in CB6F1-Tg-rasH2 mice.
2001 May
Antigenicity and immunogenicity of sulphamethoxazole: demonstration of metabolism-dependent haptenation and T-cell proliferation in vivo.
2001 May
Prevention of invasive aspergillosis in AIDS by sulfamethoxazole.
2001 May 25
Design and evaluation of drug-loaded wound dressing having thermoresponsive, adhesive, absorptive and easy peeling properties.
2001 Nov
Antimicrobial susceptibility and plasmids from Escherichia coli isolated from rats.
2001 Oct
Estimating the relative stability of polymorphs and hydrates from heats of solution and solubility data.
2001 Sep
[Guidelines for Prevention of Pneumocystis carinii Pneumonitis in Children and Adolescents with Cancer].
2001 Sep
Antimicrobial susceptibility of Haemophilus influenzae among children in Beijing, China, 1999-2000.
2002
Determination of anti-microbial susceptibilities of Haemophilus influenzae, Streptococcus pneumoniae and Moraxella catarrhalis.
2002 Feb
Role of endotoxin in 6-sulfanilamidoindazole(6SAI)-induced arthritis in rats.
2002 Feb
Brucellosis in the etiology of febrile neutropenia: case report.
2002 Feb
Linkage between toxin production and purine biosynthesis in Clostridium difficile.
2002 Jan
Bacterial infections in cirrhosis: epidemiological changes with invasive procedures and norfloxacin prophylaxis.
2002 Jan
Current treatment options for chronic granulomatous disease.
2002 Jul
Trimethoprim and sulfamethoxazole are selective inhibitors of CYP2C8 and CYP2C9, respectively.
2002 Jun
In vitro activities of pentamidine, pyrimethamine, trimethoprim, and sulfonamides against Aspergillus species.
2002 Jun
Study of different off-line sample processing procedures and the measurement of antibiotic and antiviral levels in human serum by high-performance liquid chromatography.
2002 Jun 25
Septicaemic pasteurellosis in ostriches (Struthio camelus) in central Saudi Arabia.
2002 Mar
Patents

Sample Use Guides

The usual adult dosage in the treatment of urinary tract infections and otitis media is 1 DS (double strength) tablet (each DS tablets contains 800 mg sulfamethoxazole and 160 mg trimethoprim) every 12 hours for 10 to 14 days. An identical daily dosage is used for 5 days in the treatment of shigellosis. The recommended dose for children with urinary tract infections or acute otitis media is 40 mg/kg sulfamethoxazole and 8 mg/kg trimethoprim per 24 hours, given in two divided doses every 12 hours for 10 days. An identical daily dosage is used for 5 days in the treatment of shigellosis.The usual adult dosage in the treatment of acute exacerbations of chronic bronchitis is 1 DS tablet every 12 hours for 14 days. The recommended dosage for treatment of patients with documented Pneumocystis jiroveci pneumonia is 75 to 100 mg/kg sulfamethoxazole and 15 to 20 mg/kg trimethoprim per 24 hours given in equally divided doses every 6 hours for 14 to 21 days. The recommended dosage for prophylaxis in adults is 1 DS tablet daily. For the treatment of traveler’s diarrhea, the usual adult dosage is 1 DS tablet every 12 hours for 5 days.
Route of Administration: Oral
Bacterias were treated with 23.75 ug sulfamethoxazole to test the susceptibility of microorganisms. MIC values were 38 mcg/ml (Enterobacteriaceae), 9.5 mcg/ml (Haemophilus influenzae), 9.5 mcg/ml (Streptococcus pneumoniae).
Substance Class Chemical
Created
by admin
on Mon Mar 31 18:02:01 GMT 2025
Edited
by admin
on Mon Mar 31 18:02:01 GMT 2025
Record UNII
JE42381TNV
Record Status Validated (UNII)
Record Version
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Name Type Language
AZO GANTANOL COMPONENT SULFAMETHOXAZOLE
Preferred Name English
SULFAMETHOXAZOLE
EP   HSDB   INN   MART.   MI   ORANGE BOOK   USAN   USP   USP-RS   VANDF   WHO-DD   WHO-IP  
USAN   INN  
Official Name English
RO 4-2130
Code English
sulfamethoxazole [INN]
Common Name English
SULFAMETHOPRIM COMPONENT SULFAMETHOXAZOLE
Common Name English
UROPLUS COMPONENT SULFAMETHOXAZOLE
Common Name English
NSC-147832
Code English
COTRIM COMPONENT SULFAMETHOXAZOLE
Common Name English
COTRIM D.S. COMPONENT SULFAMETHOXAZOLE
Common Name English
GANTANOL
Brand Name English
SULFAMETHOXAZOLE [USP-RS]
Common Name English
SULFAMETHOXAZOLE [MART.]
Common Name English
BACTRIM PEDIATRIC COMPONENT SULFAMETHOXAZOLE
Common Name English
SEPTRA COMPONENT SULFAMETHOXAZOLE
Common Name English
STX-608
Code English
SULFAMETHOXAZOLE [ORANGE BOOK]
Common Name English
SULFAMETHOXAZOLUM [WHO-IP LATIN]
Common Name English
BACTRIM DS COMPONENT SULFAMETHOXAZOLE
Common Name English
SULFAMETHOXAZOLE [JAN]
Common Name English
SULFATRIM COMPONENT SULFAMETHOXAZOLE
Common Name English
SULFAMETHOXAZOLE [VANDF]
Common Name English
BACTRIM COMPONENT SULFAMETHOXAZOLE
Common Name English
SULFAMETHOXAZOLE [IARC]
Common Name English
BENZENESULFONAMIDE, 4-AMINO-N-(5-METHYL-3-ISOXAZOLYL)-
Systematic Name English
SULFAMETHOXAZOLE [USP MONOGRAPH]
Common Name English
SULPHAMETHOXAZOLE
Common Name English
SULFAMETHOXAZOLE [USAN]
Common Name English
RO-4-2130
Code English
SULFAMETHOXAZOLE [MI]
Common Name English
SULMEPRIM COMPONENT SULFAMETHOXAZOLE
Common Name English
N(SUP 1)-(5-METHYL-3-ISOXAZOLYL)SULFANILAMIDE
Systematic Name English
Sulfamethoxazole [WHO-DD]
Common Name English
SULFAMETHOXAZOLE [HSDB]
Common Name English
SMX
Common Name English
Co-trimethoxazole component sulfamethoxazole
Common Name English
SULFAMETHOXAZOLE [EP MONOGRAPH]
Common Name English
SULFAMETHOXAZOLE [WHO-IP]
Common Name English
Classification Tree Code System Code
WHO-ESSENTIAL MEDICINES LIST 6.5.4 (SUL/TRI)
Created by admin on Mon Mar 31 18:02:01 GMT 2025 , Edited by admin on Mon Mar 31 18:02:01 GMT 2025
WHO-ESSENTIAL MEDICINES LIST 6.2.2 (SUL/TRI)
Created by admin on Mon Mar 31 18:02:01 GMT 2025 , Edited by admin on Mon Mar 31 18:02:01 GMT 2025
NDF-RT N0000008048
Created by admin on Mon Mar 31 18:02:01 GMT 2025 , Edited by admin on Mon Mar 31 18:02:01 GMT 2025
WHO-ATC J01EE01
Created by admin on Mon Mar 31 18:02:01 GMT 2025 , Edited by admin on Mon Mar 31 18:02:01 GMT 2025
WHO-VATC QJ01EQ11
Created by admin on Mon Mar 31 18:02:01 GMT 2025 , Edited by admin on Mon Mar 31 18:02:01 GMT 2025
WHO-VATC QJ01EW11
Created by admin on Mon Mar 31 18:02:01 GMT 2025 , Edited by admin on Mon Mar 31 18:02:01 GMT 2025
NCI_THESAURUS C29739
Created by admin on Mon Mar 31 18:02:01 GMT 2025 , Edited by admin on Mon Mar 31 18:02:01 GMT 2025
NDF-RT N0000008048
Created by admin on Mon Mar 31 18:02:01 GMT 2025 , Edited by admin on Mon Mar 31 18:02:01 GMT 2025
LIVERTOX NBK547937
Created by admin on Mon Mar 31 18:02:01 GMT 2025 , Edited by admin on Mon Mar 31 18:02:01 GMT 2025
NDF-RT N0000175504
Created by admin on Mon Mar 31 18:02:01 GMT 2025 , Edited by admin on Mon Mar 31 18:02:01 GMT 2025
WHO-ATC J04AM08
Created by admin on Mon Mar 31 18:02:01 GMT 2025 , Edited by admin on Mon Mar 31 18:02:01 GMT 2025
WHO-ATC J01EC01
Created by admin on Mon Mar 31 18:02:01 GMT 2025 , Edited by admin on Mon Mar 31 18:02:01 GMT 2025
NDF-RT N0000008048
Created by admin on Mon Mar 31 18:02:01 GMT 2025 , Edited by admin on Mon Mar 31 18:02:01 GMT 2025
Code System Code Type Description
LACTMED
Sulfamethoxazole
Created by admin on Mon Mar 31 18:02:01 GMT 2025 , Edited by admin on Mon Mar 31 18:02:01 GMT 2025
PRIMARY
CHEBI
9332
Created by admin on Mon Mar 31 18:02:01 GMT 2025 , Edited by admin on Mon Mar 31 18:02:01 GMT 2025
PRIMARY
EPA CompTox
DTXSID8026064
Created by admin on Mon Mar 31 18:02:01 GMT 2025 , Edited by admin on Mon Mar 31 18:02:01 GMT 2025
PRIMARY
FDA UNII
JE42381TNV
Created by admin on Mon Mar 31 18:02:01 GMT 2025 , Edited by admin on Mon Mar 31 18:02:01 GMT 2025
PRIMARY
WIKIPEDIA
SULFAMETHOXAZOLE
Created by admin on Mon Mar 31 18:02:01 GMT 2025 , Edited by admin on Mon Mar 31 18:02:01 GMT 2025
PRIMARY
DRUG CENTRAL
2514
Created by admin on Mon Mar 31 18:02:01 GMT 2025 , Edited by admin on Mon Mar 31 18:02:01 GMT 2025
PRIMARY
EVMPD
SUB10711MIG
Created by admin on Mon Mar 31 18:02:01 GMT 2025 , Edited by admin on Mon Mar 31 18:02:01 GMT 2025
PRIMARY
NCI_THESAURUS
C47737
Created by admin on Mon Mar 31 18:02:01 GMT 2025 , Edited by admin on Mon Mar 31 18:02:01 GMT 2025
PRIMARY
RXCUI
10180
Created by admin on Mon Mar 31 18:02:01 GMT 2025 , Edited by admin on Mon Mar 31 18:02:01 GMT 2025
PRIMARY RxNorm
WHO INTERNATIONAL PHARMACOPEIA
SULFAMETHOXAZOLE
Created by admin on Mon Mar 31 18:02:01 GMT 2025 , Edited by admin on Mon Mar 31 18:02:01 GMT 2025
PRIMARY Description: A white or yellowish white, crystalline powder; odourless. Solubility: Very slightly soluble in water; soluble in 50 parts of ethanol (~750 g/l) TS and in 3 parts of acetone R. Category: Antibacterial. Storage: Sulfamethoxazole should be kept in a well-closed container, protected from light. Definition: Sulfamethoxazole contains not less than 99.0% and not more than 101.0% of C10H11N3O3S, calculated with reference to the dried substance.
NDF-RT
N0000185504
Created by admin on Mon Mar 31 18:02:01 GMT 2025 , Edited by admin on Mon Mar 31 18:02:01 GMT 2025
PRIMARY Cytochrome P450 2C9 Inhibitors [MoA]
ECHA (EC/EINECS)
211-963-3
Created by admin on Mon Mar 31 18:02:01 GMT 2025 , Edited by admin on Mon Mar 31 18:02:01 GMT 2025
PRIMARY
MESH
D013420
Created by admin on Mon Mar 31 18:02:01 GMT 2025 , Edited by admin on Mon Mar 31 18:02:01 GMT 2025
PRIMARY
HSDB
3186
Created by admin on Mon Mar 31 18:02:01 GMT 2025 , Edited by admin on Mon Mar 31 18:02:01 GMT 2025
PRIMARY
ChEMBL
CHEMBL443
Created by admin on Mon Mar 31 18:02:01 GMT 2025 , Edited by admin on Mon Mar 31 18:02:01 GMT 2025
PRIMARY
NSC
147832
Created by admin on Mon Mar 31 18:02:01 GMT 2025 , Edited by admin on Mon Mar 31 18:02:01 GMT 2025
PRIMARY
PUBCHEM
5329
Created by admin on Mon Mar 31 18:02:01 GMT 2025 , Edited by admin on Mon Mar 31 18:02:01 GMT 2025
PRIMARY
RS_ITEM_NUM
1631001
Created by admin on Mon Mar 31 18:02:01 GMT 2025 , Edited by admin on Mon Mar 31 18:02:01 GMT 2025
PRIMARY
INN
1386
Created by admin on Mon Mar 31 18:02:01 GMT 2025 , Edited by admin on Mon Mar 31 18:02:01 GMT 2025
PRIMARY
SMS_ID
100000092618
Created by admin on Mon Mar 31 18:02:01 GMT 2025 , Edited by admin on Mon Mar 31 18:02:01 GMT 2025
PRIMARY
DAILYMED
JE42381TNV
Created by admin on Mon Mar 31 18:02:01 GMT 2025 , Edited by admin on Mon Mar 31 18:02:01 GMT 2025
PRIMARY
DRUG BANK
DB01015
Created by admin on Mon Mar 31 18:02:01 GMT 2025 , Edited by admin on Mon Mar 31 18:02:01 GMT 2025
PRIMARY
CAS
723-46-6
Created by admin on Mon Mar 31 18:02:01 GMT 2025 , Edited by admin on Mon Mar 31 18:02:01 GMT 2025
PRIMARY
LACTMED
Trimethoprim-Sulfamethoxazole
Created by admin on Mon Mar 31 18:02:01 GMT 2025 , Edited by admin on Mon Mar 31 18:02:01 GMT 2025
PRIMARY
MERCK INDEX
m10320
Created by admin on Mon Mar 31 18:02:01 GMT 2025 , Edited by admin on Mon Mar 31 18:02:01 GMT 2025
PRIMARY Merck Index
Related Record Type Details
SALT/SOLVATE -> PARENT
TARGET ORGANISM->INHIBITOR
BINDER->LIGAND
METABOLIC ENZYME -> SUBSTRATE
Related Record Type Details
METABOLITE -> PARENT
METABOLITE -> PARENT
METABOLITE REACTIVE TYPE->PARENT
METABOLITE REACTIVE TYPE->PARENT
Related Record Type Details
IMPURITY -> PARENT
IMPURITY -> PARENT
IMPURITY -> PARENT
IMPURITY -> PARENT
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Biological Half-life PHARMACOKINETIC