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Details

Stereochemistry ACHIRAL
Molecular Formula C11H13N3O3S
Molecular Weight 267.304
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of SULFATROXAZOLE

SMILES

CC1=C(C)C(NS(=O)(=O)C2=CC=C(N)C=C2)=NO1

InChI

InChIKey=DAUFGBIKKGOPJA-UHFFFAOYSA-N
InChI=1S/C11H13N3O3S/c1-7-8(2)17-13-11(7)14-18(15,16)10-5-3-9(12)4-6-10/h3-6H,12H2,1-2H3,(H,13,14)

HIDE SMILES / InChI

Description

Sulfatroxazole is a sulfamide derivative patented by Swiss multinational healthcare company F. Hoffmann-La Roche & Co., A.-G. as an antibacterial agent and bacteriostatic antibiotic. Sulfatroxazole competitively inhibits dihydropteroate synthase preventing the formation of dihydropteroic acid, a precursor of folic acid which is required for bacterial growth. Sulfatroxazole is a component present in various veterinary drugs.

Originator

Approval Year

Targets

Primary TargetPharmacologyConditionPotency
260.0 nM [IC50]

PubMed

Patents