U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS
This repository is under review for potential modification in compliance with Administration directives.

Showing 1 - 10 of 25 results

Status:
US Approved OTC
First approved in 1984

Class (Stereo):
CHEMICAL (ACHIRAL)

Conditions:

Benzoyl peroxide (BPO) is an organic compound in the peroxide family. It consists of two benzoyl groups bridged by a peroxide link. It is one of the most important organic peroxides in terms of applications and the scale of its production. Benzoyl pe...
Status:
US Approved OTC
First approved in 1975

Class (Stereo):
CHEMICAL (ACHIRAL)



Clotrimazole is an anti-fungal medicine indicated for the treatment of vaginal yeast infections and tinea. It can be used either in combination with other drugs (betamethasone dipropionate) or alone, in form of topical or vaginal cream. The drug exer...
Status:
US Approved OTC
First approved in 1971

Class (Stereo):
CHEMICAL (ACHIRAL)


Haloprogin is an active synthetic antifungal and antimonilial agent that was effective in the treatment of superficial fungal and monilial infections of the skin. Because of these two basic therapeutic effects, haloprogin was especially useful in the...
Status:
US Approved OTC
First approved in 1965

Class (Stereo):
CHEMICAL (ACHIRAL)



Tolnaftate is a thiocarbamate derivative used as an over-the-counter anti-fungal agent for treatment of athlete's foot and ringworm. Tolnaftate acts by inhibition of ergosterol biosynthesis pathway in fungal cells.
Status:
US Approved OTC
First approved in 1961

Class (Stereo):
CHEMICAL (ACHIRAL)


Clioquinol is a broad-spectrum antibacterial with antifungal properties, bacteriostatic. It is used as an antifungal and antiprotozoal topical drug OTC product for treatment of human infections. Previousely was used for wide number of intestinal diso...
Status:
US Approved OTC
First approved in 1961

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

Calcium Undecylenate is the calcium salt of undecylenic acid, an 11 carbon mono-unsaturated fatty acid with broad-spectrum antifungal activity. Undecylenic acid inhibits the morphogenesis of Candida albicans to its invasive fungal form and inhibits t...
Status:
US Approved OTC
First approved in 1961

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

Copper undecylenate was used for the therapy of cutaneous dermatomycoses combined with a wetting agent and dissolved in a fat-solvent base. Undecylenic acid inhibits the morphogenesis of Candida albicans to its invasive fungal form and inhibits conve...
Status:
US Approved OTC
First approved in 1945

Class (Stereo):
CHEMICAL (ACHIRAL)



Undecylenic acid is unsaturated fatty acid, which naturally occurs in sweat, and is commercially produced by the vacuum distillation of castor bean oil. It is recognized as GRASE by FDA, and is marketed over the counter to treat skin infections and t...
Status:
US Approved OTC
First marketed in 1906

Class (Stereo):
CHEMICAL (ACHIRAL)

Conditions:

Resorcinol Acetate is used as an ingredient to reduce the number of acne blemishes, acne pimples, blackheads, and whiteheads. In the United States, anti-acne agents are regulated as Over-the-Counter (OTC) drug ingredients. Resorcinol Acetate is also ...
Status:
US Approved OTC
First marketed in 1894

Class (Stereo):
CHEMICAL (ACHIRAL)



Resorcinol is a benzenediol. Resorcinol is commonly used in hair dyes and acne medication. Resorcinol works by breaking down rough, scaly, or hardened skin. Resorcinol also disinfects the skin to help fight infection. Resorcinol topical (for the skin...