CALCIUM UNDECYLENATE

US Approved OTC

First approved in 1961

Details

Stereochemistry	ACHIRAL
Molecular Formula	2C11H19O2.Ca
Molecular Weight	406.613
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[Ca++].[O-]C(=O)CCCCCCCCC=C.[O-]C(=O)CCCCCCCCC=C

InChI

InChIKey=CLOKKBBIKHZGNX-UHFFFAOYSA-L

InChI=1S/2C11H20O2.Ca/c2*1-2-3-4-5-6-7-8-9-10-11(12)13;/h2*2H,1,3-10H2,(H,12,13);/q;;+2/p-2

HIDE SMILES / InChI

Molecular Formula	C11H19O2
Molecular Weight	183.2674
Charge	-1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	Ca
Molecular Weight	40.078
Charge	2
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/14434921

Calcium Undecylenate is the calcium salt of undecylenic acid, an 11 carbon mono-unsaturated fatty acid with broad-spectrum antifungal activity. Undecylenic acid inhibits the morphogenesis of Candida albicans to its invasive fungal form and inhibits the conversion of unicellular yeast to their hyphal form.

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Fatty acid biosynthesis 8 Target ID: map00061 Sources: https://www.ncbi.nlm.nih.gov/pubmed/10991877	Inhibitor 8297

Conditions

Condition	Modality	Targets	Highest Phase	Product
Dermatomycosis 20 Sources: https://www.ncbi.nlm.nih.gov/pubmed/14434921	Primary		Not Provided 504	Unknown Approved Use Unknown

Sourcing

Vendor/Aggregator	ID	URL
3B Scientific (Wuhan) Corp	3B3-054229	http://www.3bsc.com/index/pro_info.php?id=92700
ABI Chem	AC1L24PI
AK Scientific, Inc. (AKSCI)	6648AF	http://www.aksci.com/item_detail.php?cat=6648AF
AmicBase - Antimicrobial Activities	6091
Avantor Inc	700013-776	https://us.vwr.com/store/product/21572644/calcium-undecylenate-98-0
Avantor Inc	700013-778	https://us.vwr.com/store/product/21572644/calcium-undecylenate-98-0
Avantor Inc	700013-782	https://us.vwr.com/store/product/21572644/calcium-undecylenate-98-0
BOC Sciences	1322-14-1	https://www.bocsci.com/calcium-undecylenate-cas-1322-14-1-item-48341.html
Clearsynth	CS-DV-03518	https://www.clearsynth.com/en/CSDV03518.html
PubChem	14865	https://pubchem.ncbi.nlm.nih.gov/compound/14865
PubChem	91886408	https://pubchem.ncbi.nlm.nih.gov/compound/91886408
Smolecule	S563221	https://www.smolecule.com/products/s563221
iChemical	EBD74208	http://www.ichemical.com/products/1322-14-1.html?utm_source=PubChem&utm_medium=website&utm_campaign=product%20catalogs

PubMed

Title	Date	PubMed
Effect of pH on the antifungal activity of undecylenic acid and its calcium salt.	1959 Dec	14434921

Patents

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

The antimicrobial activities of undecylenic acid and its calcium salt are from 5 to 30 /mkg per ml at pH 6.0 for all dermatophytes studied. The effect of pH on the rate of growth was determined by measurement of colony diameters of Trichophyton mentagrophytes grown on the surface of glucose-tryptose agar plates Ten plates were inoculated for each pH, incubated at 25 C, and read after 10 days.

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:11:55 GMT 2023` Edited by `admin` on `Fri Dec 15 15:11:55 GMT 2023`
Record UNII	77YW1RTU8V
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

CALCIUM UNDECYLENATE

Official Name

English

CALCIUM UNDECENOATE

Systematic Name

English

UNDECYLENATE CALCIUM

Common Name

English

CALCIUM UNDECENOATE [MART.]

Common Name

English

CRUEX

Brand Name

English

Calcium 10-undecenoate

Systematic Name

English

UNDECYLENATE CALCIUM [VANDF]

Common Name

English

CALCIUM UNDECYLENATE [INCI]

Common Name

English

CALCIUM UNDECYLENATE [USAN]

Common Name

English

Calcium undecenoate [WHO-DD]

Common Name

English

CALCIUM UNDECYLENATE [USP MONOGRAPH]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C514