U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 7011 - 7020 of 167129 results

Status:
Investigational
Source:
INN:flumeridone [INN]
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

FLUMERIDONE is an antiemetic agent.
Status:
Investigational
Source:
INN:salfluverine
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
Investigational
Source:
INN:flutomidate [INN]
Source URL:

Class (Stereo):
CHEMICAL (RACEMIC)

Flutomidate was studied as a hypnotic agent. Information about the current use of this agent is not available.
Status:
Investigational
Source:
INN:setoperone
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)



Setoperone is and antagonist of the brain serotonin 5-HT2 receptor and particular the 5-HT2A isoform. Setoperone is radiolabeled with the radioisotope fluorine-18 and is used in positron emission tomography (PET) in neuroimaging for the study neuropsychiatric disorders, such as schizophrenia and depression.
Status:
Investigational
Source:
INN:nifurprazine
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

The nitrofuran derivative, nifurprazine, is a topical antibacterial agent used mainly for the treatment of animal diseases. It is a trypanocidal drug. Nifurprazine proved to be the most promising derivative since it was redox-cycled by both T. cruzi LipDH and TR and had pronounced antiparasitic effects in cultures of T. cruzi and Trypanosoma brucei.
Status:
Investigational
Source:
INN:etoloxamine [INN]
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Etoloxamine is an antihistamine.
Status:
Investigational
Source:
INN:etolorex
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Etolorex is an anorectic agent.
Status:
Investigational
Source:
INN:etriciguat
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Etriciguat is a novel potent, selective, orally available soluble guanylate cyclase (sGC) stimulator.
Status:
Investigational
Source:
INN:ropizine
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Ropizone (SC-13504) is an anticonvulsant. This compound both enhances and inhibits [3H]dextromethorphan (DM) high-affinity binding to different areas of the guinea pig brain, suggesting distinct binding site types in the brain. Ropizone was shown to have limited anti-convulsant activity against chemically induced seizures. The drug may have anti-grand mal activity but lacked any anti-petit mal effect in Beagle dogs. No information on the current use of this compound is available.
Status:
Investigational
Source:
INN:rosaramicin
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Rosamaricin is a macrolide antibiotic similar to erythromycin. This compound is more effective against Gram-negative bacteria than erythromycin, especially in the prostate where rosamaricin was shown to be more concentrated than erythromycin in dogs. Rosamaricin has antibiotic activity against Neisseria gonorrhoeae, Chlamydia trachomatis, Ureaplasma urealyticum and Mycoplasma hominis. When the drug was compared with penicillin G in the treatment of pneumococcal meningitis in rabbits it was found to be less effective than penicillin G, as measured by bacterial clearance from cerebrospinal fluid and by treatment outcome. No information on the current use of this compound is available.

Showing 7011 - 7020 of 167129 results