ETRICIGUAT

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C22H16FN7
Molecular Weight	397.4077
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of ETRICIGUAT

Structure Search

SMILES

NC1=NC(=NC=C1C2=CC=NC=C2)C3=NN(CC4=C(F)C=CC=C4)C5=C3C=CC=N5

InChI

InChIKey=VAIBMQLMFYXTLJ-UHFFFAOYSA-N

InChI=1S/C22H16FN7/c23-18-6-2-1-4-15(18)13-30-22-16(5-3-9-26-22)19(29-30)21-27-12-17(20(24)28-21)14-7-10-25-11-8-14/h1-12H,13H2,(H2,24,27,28)

HIDE SMILES / InChI

Molecular Formula	C22H16FN7
Molecular Weight	397.4077
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: http://www.probechem.com/products_Etriciguat.aspx | https://www.who.int/medicines/services/inn/Add3-2008-stembook.pdf | https://patents.google.com/patent/WO2003086407A1/en

Etriciguat is a novel potent, selective, orally available soluble guanylate cyclase (sGC) stimulator.

Originator

Approval Year

Patents

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:21:40 GMT 2025` Edited by `admin` on `Mon Mar 31 18:21:40 GMT 2025`
Record UNII	E3ZEH4F4CA
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ETRICIGUAT

Official Name

English

Etriciguat [WHO-DD]

Preferred Name

English

etriciguat [INN]

Common Name

English

2-(1-(2-FLUOROBENZYL)-1H-PYRAZOLO(3,4-B)PYRIDIN-3-YL)-5-(4-PYRIDYL)PYRIMIDIN-4-AMINE

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29707

Created by admin on Mon Mar 31 18:21:40 GMT 2025 , Edited by admin on Mon Mar 31 18:21:40 GMT 2025

Code System Code Type Description

ChEMBL

CHEMBL2107749

Created by admin on Mon Mar 31 18:21:40 GMT 2025 , Edited by admin on Mon Mar 31 18:21:40 GMT 2025

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EPA CompTox

DTXSID00193244

Created by admin on Mon Mar 31 18:21:40 GMT 2025 , Edited by admin on Mon Mar 31 18:21:40 GMT 2025

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CAS

402595-29-3

Created by admin on Mon Mar 31 18:21:40 GMT 2025 , Edited by admin on Mon Mar 31 18:21:40 GMT 2025

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PUBCHEM

213019

Created by admin on Mon Mar 31 18:21:40 GMT 2025 , Edited by admin on Mon Mar 31 18:21:40 GMT 2025

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FDA UNII

E3ZEH4F4CA

Created by admin on Mon Mar 31 18:21:40 GMT 2025 , Edited by admin on Mon Mar 31 18:21:40 GMT 2025

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INN

8316

Created by admin on Mon Mar 31 18:21:40 GMT 2025 , Edited by admin on Mon Mar 31 18:21:40 GMT 2025

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SMS_ID

100000141212

Created by admin on Mon Mar 31 18:21:40 GMT 2025 , Edited by admin on Mon Mar 31 18:21:40 GMT 2025

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EVMPD

SUB91133

Created by admin on Mon Mar 31 18:21:40 GMT 2025 , Edited by admin on Mon Mar 31 18:21:40 GMT 2025

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NCI_THESAURUS

C65602

Created by admin on Mon Mar 31 18:21:40 GMT 2025 , Edited by admin on Mon Mar 31 18:21:40 GMT 2025

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					E3ZEH4F4CA

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