ROPIZINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C24H26N4
Molecular Weight	370.49
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC1=CC=CC(\C=N\N2CCN(CC2)C(C3=CC=CC=C3)C4=CC=CC=C4)=N1

InChI

InChIKey=UZDGLRYWBSKLQY-NCELDCMTSA-N

InChI=1S/C24H26N4/c1-20-9-8-14-23(26-20)19-25-28-17-15-27(16-18-28)24(21-10-4-2-5-11-21)22-12-6-3-7-13-22/h2-14,19,24H,15-18H2,1H3/b25-19+

HIDE SMILES / InChI

Molecular Formula	C24H26N4
Molecular Weight	370.49
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	1
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/639771 | https://www.ncbi.nlm.nih.gov/pubmed/762654 | https://www.ncbi.nlm.nih.gov/pubmed/2345483

Ropizone (SC-13504) is an anticonvulsant. This compound both enhances and inhibits [3H]dextromethorphan (DM) high-affinity binding to different areas of the guinea pig brain, suggesting distinct binding site types in the brain. Ropizone was shown to have limited anti-convulsant activity against chemically induced seizures. The drug may have anti-grand mal activity but lacked any anti-petit mal effect in Beagle dogs. No information on the current use of this compound is available.

Approval Year

PubMed

Title	Date	PubMed

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:12:02 GMT 2023` Edited by `admin` on `Fri Dec 15 16:12:02 GMT 2023`
Record UNII	Q5128GW9D4
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

ROPIZINE

Official Name

English

NSC-300584

Code

English

SC-13504

Code

English

ropizine [INN]

Common Name

English

ROPIZINE [USAN]

Common Name

English

1-(Diphenylmethyl)-4-[[(6-methyl-2-pyridyl)methylene]amino]piperazine

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C264